Results 51 to 60 of about 22,892 (257)
Novel transmembrane receptor involved in phagosome transport of lysozymes and β-hexosaminidase in the enteric protozoan Entamoeba histolytica. [PDF]
PLoS Pathogens, 2012 Lysozymes and hexosaminidases are ubiquitous hydrolases in bacteria and eukaryotes. In phagocytic lower eukaryotes and professional phagocytes from higher eukaryotes, they are involved in the degradation of ingested bacteria in phagosomes.
Atsushi Furukawa +2 more
doaj +1 more source
Determinants of Phagosomal pH During Host-Pathogen Interactions
Frontiers in Cell and Developmental Biology, 2021 The ability of phagosomes to halt microbial growth is intimately linked to their ability to acidify their luminal pH. Establishment and maintenance of an acidic lumen requires precise co-ordination of H+ pumping and counter-ion permeation to offset the ...
Johannes Westman +2 more
doaj +1 more source
Acidification of phagosomes containing different phagocytic particles. [PDF]
, 2012 Phagosome acidification was assessed with Lysotracker red. A) Lysotracker staining of a SMC containing a negative phagosome. B) Engulfed agRBC stained with CFSE. C) Corresponding merged image.
Luís M. B. B. Estronca (123414) +2 more
core +1 more source
PLoS ONE, 2011 Burkholderia pseudomallei is the causative agent of melioidosis, a fatal infectious disease endemic in tropical regions worldwide, and especially prevalent in southeast Asia and northern Australia.
Lan Gong +7 more
doaj +1 more source
TAP is present in highly pure Mtb phagosomes. [PDF]
, 2013 Mtb-containing phagosomes were stained with antibodies against A) LAMP1; B) HLA-I; C) TAP2 (2.17); or D) TOM20, a Golgi marker used as a negative control; and imaged on a high-resolution wide field Core DV system. One 0.2 um Z-section is shown.
David M. Lewinsohn (266240) +5 more
core +1 more source
The Formation and Renewal of Photoreceptor Outer Segments
CellsThe visual system is essential for humans to perceive the environment. In the retina, rod and cone photoreceptor neurons are the initial sites where vision forms.
Jingjin Xu, Chengtian Zhao, Yunsi Kang
doaj +1 more source
Frontiers in Immunology, 2011 Lysosome mobilization is a key cellular process in phagocytes for bactericidal activities and trans-matrix migration. The molecular mechanisms that regulate lysosome mobilization are still poorly known.
Arnaud M. Labrousse +8 more
doaj +1 more source
Anisotropic presentation of ligands on cargos modulates degradative function of phagosomes
Biophysical Reports, 2022 Anisotropic arrangement of cell wall components is ubiquitous among bacteria and fungi, but how such functional anisotropy affects interactions between microbes and host immune cells is not known.
Mengchi Jiao +3 more
doaj +1 more source
Mtb phagosomes contain minimal contamination. [PDF]
, 2013 (A) HLA-A2− or HLA-A2+ DC were infected with H37Rv-eGFP for 20 minutes, washed, and incubated for an additional 40 minutes. HLA-A2− DC were mixed with uninfected HLA-A2+ DC, homogenized, and homogenate separated using 27% percoll as described or pelleted
David M. Lewinsohn (266240) +6 more
core +1 more source
Biochemical Society Transactions, 1986 Phagosome-lysosome fusion plays an important role in the destruction of micro-organisms by phagocytic cells. Several approaches have been used to study the determinants of phagosome-lysosome fusion in mouse macrophages. Fusion can be assayed by electron microscopy using horseradish peroxidase or thorium dioxide as a marker for secondary lysosomes or by
Gabay, JE, Horwitz, MA, Cohn, ZA
openaire +4 more sources