SpeedMixing: Rapid Synthesis and Discovery of Model Pharmaceutical Cocrystals without Milling or Grinding Media [PDF]
, 2022 Yong Teoh +6 more
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In Silico Coformer Screening for Mefenamic Acid Cocrystallization
Jurnal Info KesehatanCocrystallization is a widely used approach to enhance the solubility and dissolution characteristics of poorly soluble drugs. A pharmaceutical cocrystal is a multicomponent system composed of a solid active pharmaceutical ingredient (API) and a coformer,
Aulia Fikri Hidayat +3 more
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Crystal Engineering of Pharmaceutical Cocrystals
, 2011 Cocrystals have recently gained attention as attractive alternate solid forms for drug development. A pharmaceutical cocrystal is a single crystalline homogenous phase consisting of a drug molecule and ligand i.e. cocrystal former that is excipient or another drug molecule [1,2].
Cvetkovski, Aleksandar, Gulaboski, Rubin
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Formation of Pharmaceutical Salts and Cocrystals via Vapour-Assisted Tumbling (VAT) – A Solvent Efficient Process with Potential Industrial Applications [PDF]
, 2021 Alexander J. Stirk +5 more
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Towards continuous production of pharmaceutical cocrystals
, 2014 A novel method for the simultaneous production and formulation of pharmaceutical cocrystals, matrix-assisted cocrystallization (MAC), using hot-melt extrusion by coprocessing the drug and conformer has been developed. Three model drugs were used, a coformer, and matrix, respectively.
Kevin Boksa, Andrew Otte, Rodolfo Pinal
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Advances in Quantitative Analytical Methods for Solid Drugs
CrystalsThe solid form of the drug can directly affect the physicochemical properties, bioavailability, safety, and efficacy of the drug, and its types mainly include amorphous state, single-component polycrystalline, hydrate, solvate, salt, and cocrystal ...
Yue Tao +7 more
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Pharmaceutical Cocrystals for Improving Physicochemical Properties of Drugs [PDF]
Debabrata Ghosh Dastidar +3 more
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Current status and promising future of pharmaceutical cocrystals in development of oral dosage forms
, 2017 Toshiro Fukami
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Pharmaceutical Cocrystals: New Solid Phase Modification Approaches for the Formulation of APIs [PDF]
, 2018 Anna Karagianni +2 more
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