Results 121 to 130 of about 2,679 (172)

Strategic Modulation of Isoniazid Solubility through Cocrystal Formation for Long-Acting Microneedle Therapy of Tuberculosis. [PDF]

ACS Appl Mater Interfaces
Fandiño OE, McPeake LK, Li H, Li Y, Donnelly RF.   +4 more
europepmc   +1 more source

Machine learning analysis of pharmaceutical cocrystals solubility parameters in enhancing the drug properties for advanced pharmaceutical manufacturing. [PDF]

Sci Rep
Alharby TN, Huwaimel B.
europepmc   +1 more source

A Novel Temozolomide-Myricetin Drug-Drug Cocrystal: Preparation, Characterization, Property Evaluations. [PDF]

Pharmaceutics
Qin HX, Wang J, Peng JH, Dai XL, Li CW, Lu TB, Chen JM.   +6 more
europepmc   +1 more source

The Potential of Microwave Radiation and Mechanochemistry in the Formation of Purine Alkaloids Cocrystals Using Pyromellitic Acid as a Coformer: Synthesis, Structural, Spectroscopic, Thermal Analysis, and Biological Properties. [PDF]

Cryst Growth Des
Cal W, Gołdyn MR, Grupa O, Starzyk J, Larowska-Zarych D, Frąckowiak K, Bartoszak-Adamska E.   +6 more
europepmc   +1 more source

Co-crystallization in Antiepileptic Drugs: A Path Toward Better Therapeutic Outcomes. [PDF]

Cureus
Patil B, Surana S, Shirkhedkar A.
europepmc   +1 more source

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Pharmaceutical Cocrystal: An Antique and Multifaceted Approach

Current Drug Delivery, 2017
Pharmaceutical cocrystal is an emerging approach to tailor physicochemical and mechanical properties of drug substances. Cocrystals are composed of API and pharmaceutically acceptable coformer. It is used to address the solubility, dissolution, mechanical properties and stability of drugs.This review discusses introduction to cocrystal, preparation ...
Prabhakar Satwaji Panzade
exaly   +3 more sources

Stability screening of pharmaceutical cocrystals

Pharmaceutical Development and Technology, 2021
An efficient protocol for assessing both the chemical and physical stability of cocrystalline forms of active pharmaceutical ingredients (APIs) is proposed. In this protocol, the cocrystalline material is used to prepare two standard formulations, mimicking wet granulations, to make low-dose tablets.
Kenneth C, Waterman, Alisa K, Waterman, Teslin M, Botoy, Jane, Li, Fenghe, Qiu, Michael, Hawley   +5 more
openaire   +2 more sources

Cocrystal: A Review on the Design and Preparation of Pharmaceutical Cocrystals

Asian Journal of Research in Pharmaceutical Sciences, 2023
The majority of the active pharmaceutical components have issues with poor solubility, bioavailability, chemical stability, and moisture absorption. Pharmaceutical crystals are a reliable way to change the aforementioned physicochemical properties of drugs without changing their pharmacological behaviour.
Tanmay Jit, Dibyendu Shil, Ramesh Kumari Dasgupta, Sanglap Mallick, Saptarshi Mukherjee   +4 more
openaire   +1 more source

Pharmaceutical cocrystals: An overview

International Journal of Pharmaceutics, 2011
Pharmaceutical cocrystals are emerging as a new class of solid drugs with improved physicochemical properties, which has attracted increased interests from both industrial and academic researchers. In this paper a brief and systematic overview of pharmaceutical cocrystals is provided, with particular focus on cocrystal design strategies, formation ...
Qiao, N., Li, M., Schlindwein, W. S., Malek, Nazneen, Davies, Angela, Trappitt, Gary   +5 more
openaire   +3 more sources

The role of cocrystals in pharmaceutical science

Drug Discovery Today, 2008
Pharmaceutical cocrystals, a subset of a long known but little-studied class of compounds, represent an emerging class of crystal forms in the context of pharmaceutical science. They are attractive to pharmaceutical scientists because they can significantly diversify the number of crystal forms that exist for a particular active pharmaceutical ...
Ning, Shan, Michael J, Zaworotko
openaire   +2 more sources