Results 141 to 150 of about 2,679 (172)
Some of the next articles are maybe not open access.
ChemInform Abstract: Pharmaceutical Cocrystals
ChemInform, 2011AbstractReview: 98 refs.
Ning Qiao +5 more
openaire +1 more source
Solubility Advantage of Pharmaceutical Cocrystals
Crystal Growth & Design, 2009Pharmaceutical cocrystals can improve solubility, dissolution, and bioavailability of poorly water soluble drugs. However, true cocrystal solubility is not readily measured for highly soluble cocrystals because they can transform to the most stable drug form in solution.
David J. Good, Naír Rodríguez-Hornedo
openaire +1 more source
Impact of pharmaceutical cocrystals: the effects on drug pharmacokinetics
Expert Opinion on Drug Metabolism & Toxicology, 2014Pharmaceutical cocrystallization has emerged in the past decade as a new strategy to enhance the clinical performance of orally administered drugs. A pharmaceutical cocrystal is a multi-component crystalline material in which the active pharmaceutical ingredient is in a stoichiometric ratio with a second compound that is generally a solid under ambient
Ning, Shan +3 more
openaire +2 more sources
Pharmaceutical cocrystals: along the path to improved medicines
Chemical Communications, 2016Cocrystals, a long known but understudied class of crystalline solids, have attracted interest from crystal engineers and pharmaceutical scientists in the past decade and are now an integral part of the preformulation stage of drug development.
Naga K, Duggirala +3 more
openaire +2 more sources
Cocrystal Systems of Pharmaceutical Interest: 2009
2011As scientists become more aware of a substantial expansion in the scope of solid-state structural variations that can be obtained through the cocrystallization of several molecules in a single lattice structure, studies of the mixed molecular crystal systems known as cocrystals have mushroomed. Along these lines, workers have researched the assembly of
openaire +2 more sources
Mass transport of pharmaceutical cocrystals
2018<p>Cocrystals have two or more neutral components (drug and cocrystal former) in the same crystal lattice which are held together via non-covalent bonds. Since the presence of the cocrystal former alters the energy of the drug molecules and their physicochemical properties, the drug dissolution characteristics can be manipulated by ...
Hui Zu +6 more
openaire +1 more source
Crystal Engineering of Pharmaceutical Cocrystals [PDF]
, 2011 Cocrystals have recently gained attention as attractive alternate solid forms for drug development. A pharmaceutical cocrystal is a single crystalline homogenous phase consisting of a drug molecule and ligand i.e. cocrystal former that is excipient or another drug molecule [1,2].
Cvetkovski, Aleksandar, Gulaboski, Rubin
openaire
Research Progress of Plant Active Ingredients in Pharmaceutical Cocrystal
Current Drug Delivery, 2023Zimeng Wang +2 more
exaly