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Pharmacogenetics and pharmacogenomics [PDF]

open access: bronzeBritish Journal of Clinical Pharmacology, 2001
Abstract Pharmacogenetics, the study of genetic differences that affect an individual's response to drugs, has outstanding potential to maximize benefit and minimize harm associated with drug therapy. Our rapidly increasing knowledge of all genes in the human genome, together with the development of multiparallel, next generation sequencing ...
Munir Pirmohamed
openalex   +5 more sources

Pharmacogenomic Biomarkers [PDF]

open access: greenDisease Markers, 2003
Pharmacogenomic biomarkers hold great promise for the future of medicine and have been touted as a means to personalize prescriptions. Genetic biomarkers for disease susceptibility including both Mendelian and complex disease promise to result in improved understanding of the pathophysiology of disease, identification of new potential therapeutic ...
Kirkwood, Sandra C., Hockett, Richard D.
openalex   +4 more sources

Economic evaluations of pharmacogenetic and pharmacogenomic screening tests : a systematic review : second update of the literature [PDF]

open access: yes, 2016
Objective : Due to extended application of pharmacogenetic and pharmacogenomic screening (PGx) tests it is important to assess whether they provide good value for money. This review provides an update of the literature. Methods : A literature search was
Annemans, Lieven   +7 more
core   +17 more sources

Complexity and Pharmacogenomics [PDF]

open access: bronzeThe Pharmacogenomics Journal, 2002
Júlio Licinio, Ma‐Li Wong
openalex   +3 more sources

Pharmacogenomics of Antibiotics [PDF]

open access: yesInternational Journal of Molecular Sciences, 2020
Although the introduction of antibiotics in medicine has resulted in one of the most successful events and in a major breakthrough to reduce morbidity and mortality caused by infectious disease, response to these agents is not always predictable, leading to differences in their efficacy, and sometimes to the occurrence of adverse effects.
Stocco G., Lucafo M., Decorti G.
openaire   +5 more sources

Knowledge, attitude and perception of community pharmacists towards pharmacogenomics services in northern Nigeria: a cross-sectional study

open access: yesJournal of Pharmaceutical Policy and Practice, 2022
Objectives To evaluate knowledge, attitude and perception of community pharmacists towards pharmacogenomics services. Methods A cross-sectional study was conducted among community pharmacists in two cities in Northern Nigeria using a self-administered ...
Usman Abubakar   +7 more
doaj   +1 more source

Pharmacogenomics and Morphine [PDF]

open access: yesThe Journal of Clinical Pharmacology, 2021
AbstractMorphine is an opioid analgesic indicated in the treatment of acute and chronic moderate to severe pain. From a pharmacodynamic standpoint, morphine exerts its effects by agonizing mu‐opioid receptors predominantly, resulting in analgesia and sedation.
Adaku Ofoegbu, Earl B. Ettienne
openaire   +3 more sources

Development of the pharmacogenomics and genomics literacy framework for pharmacists

open access: yesHuman Genomics, 2021
Background Pharmacists play a unique role in integrating genomic medicine and pharmacogenomics into the clinical practice and to translate pharmacogenomics from bench to bedside. However, the literature suggests that the knowledge gap in pharmacogenomics
Azhar T. Rahma   +6 more
doaj   +1 more source

Investigation of Biomedical Students’ Attitudes toward Pharmacogenomics and Personalized Medicine: A Cross-Sectional Study

open access: yesPharmacy, 2022
Background: The utilization of pharmacogenomics in everyday practice has shown several notable benefits. Keeping in mind the rising trend of applicability of pharmacogenomics and personalized medicine, we sought to compare the attitudes of future ...
Josipa Bukic   +7 more
doaj   +1 more source

Pharmacogenomic testing and its future in community pharmacy [PDF]

open access: yes, 2020
Although it is common to see pharmacogenomic testing used North America and Australia, it is not yet part of practice in the UK. With the promise of genomic screening becoming part of the NHS, pharmacists must equip themselves with a knowledge of how the
Wright, David, Youssef, Essra
core   +1 more source

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