Results 171 to 180 of about 74,509 (297)

Implementation of mass pharmacogenetic testing: Dihydropyrimidine dehydrogenase testing prior to fluoropyrimidine treatment for patients

open access: yesBritish Journal of Clinical Pharmacology, Volume 91, Issue 9, Page 2534-2542, September 2025.
Aims Pharmacogenomics enables personalization of drug therapy improving effectiveness and/or safety. Dihydropyrimidine dehydrogenase [DPYD] testing prior to fluoropyrimidine chemotherapy was commissioned by NHS England in response to an update from the Medicines and Healthcare products Regulatory Agency.
Nisha Shaunak   +5 more
wiley   +1 more source

Decoding Stroke Etiology: Multi‐Omics Advancements in Genetic Mechanisms and Clinical Implication

open access: yesBrain and Behavior, Volume 15, Issue 9, September 2025.
This review systematically presents multi‐omics achievements in understanding the genetic susceptibility to stroke, including related risk genes, rare variations, CNVs, and epigenetic influences. Furthermore, it critically examines the clinical implications of these genetic discoveries for advancing personalized medicine, particularly in optimizing ...
Renxia Xiao   +4 more
wiley   +1 more source

Navigating Pharmacogenomic Testing in Practice: Who to Test and When to Test

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 3, Page 561-566, September 2025.
There is increasing attention on the clinical utility and value of pharmacogenetic (PGx) testing to individualize medication management. Most clinical practice guidelines from medical professional societies do not recommend routine PGx testing, with a few key exceptions.
James M. Stevenson   +4 more
wiley   +1 more source

Dietary Phytochemicals in Cardiovascular Disease Prevention and Management: A Comprehensive Review

open access: yesFood Science &Nutrition, Volume 13, Issue 9, September 2025.
The main purpose of this research is to gather the latest scientific evidence on the role of phytochemicals in food, as far as their prevention and management of cardiovascular diseases is concerned. Existing clinical and epidemiological evidence establishes the health benefits of phytochemicals, and this research hopes to evaluate these advantages and
Muhammad Tayyab Arshad   +7 more
wiley   +1 more source

Pharmacogenomic studies using paraffin embedded tumor samples [PDF]

open access: green, 2003
James M. Rae   +3 more
openalex   +1 more source

Cancer of the ovary, fallopian tube, and peritoneum: 2025 update

open access: yesInternational Journal of Gynecology &Obstetrics, Volume 171, Issue S1, Page 6-35, September 2025.
Abstract In 2014, FIGO's Committee for Gynecologic Oncology revised the staging of ovarian cancer, incorporating ovarian, fallopian tube, and peritoneal cancer into the same system. Most of these malignancies are high‐grade serous carcinomas (HGSCs).
Malte Renz   +2 more
wiley   +1 more source

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