Results 1 to 10 of about 865,562 (415)

Pharmacokinetics, absolute bioavailability and tolerability of ketamine after intranasal administration to dexmedetomidine sedated dogs [PDF]

, 2020
Intranasal ketamine has recently gained interest in human medicine, not only for its sedative, anaesthetic or analgesic properties, but also in the management of treatment resistant depression, where it has been shown to be an effective, fast acting ...
Croubels, Siska, Devreese, Mathias, Dockx, Robrecht, Duchateau, Luc, Peremans, Kathelijne, Polis, Ingeborgh, Vlerick, Lise   +6 more
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Tumor necrosis factor inhibitors in psoriatic arthritis. [PDF]

, 2017
INTRODUCTION: Psoriatic arthritis (PsA) is a chronic inflammatory disease that can result in significant disability. With the emergence of tumor necrosis factor inhibitors (TNFi), therapeutic outcomes in PsA have improved substantially.
Kraft, Walter K., Mantravadi, Santhi, Ogdie, Alexis   +2 more
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Population Pharmacokinetics and Pharmacodynamics of Artemether and Lumefantrine During Combination Treatment in Children with Uncomplicated Falciparum Malaria in Tanzania. [PDF]

, 2010
The combination of artemether (ARM) and lumefantrine is currently the first-line treatment of uncomplicated falciparum malaria in mainland Tanzania. While the exposure to lumefantrine has been associated with the probability of adequate clinical and ...
Hietala, Sofia Friberg, Mårtensson, Andreas, Ngasala, Billy, Dahlström, Sabina, Lindegårdh, Niklas, Annerberg, Anna, Premji, Zul, Färnert, Anna, Gil, Pedro, Björkman, Anders, Ashton, Michael   +10 more
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Therapeutic and toxic blood concentrations of nearly 1,000 drugs and other xenobiotics [PDF]

, 2012
Introduction: In order to assess the significance of drug levels measured in intensive care medicine, clinical and forensic toxicology, as well as for therapeutic drug monitoring, it is essential that a comprehensive collection of data is readily ...
Andresen, Hilke, Iwersen-Bergmann, Stefanie, Schmoldt, Achim, Schulz, Martin   +3 more
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Personalizing HIV therapy, mission impossible? [PDF]

, 2012
Sustained HIV suppression depends on a number of factors including therapy adherence, management of side effects, viral resistance and individual characteristics of patients and therapeutic settings.
Hentig, Nils von
core   +1 more source

Medication Complications in Extracorporeal Membrane Oxygenation. [PDF]

, 2017
The need for extracorporeal membrane oxygenation (ECMO) therapy is a marker of disease severity for which multiple medications are required. The therapy causes physiologic changes that impact drug pharmacokinetics.
Aebi, Ami G. Shah, Anderson, Arlt, Barr, Barthelemy, Beiderlinden, Bein, Bembea, Bhatt-Meht, Boucher, Brandi N. Thoma, Brown, Buck, Buscher, Chung, Dagan, Dagan, de Montmollin, De Rosa, DeGrado, Donadello, Donadello, Dzierba, Erstad, Esper, Eyler, Flordelis Lasierra, Glauber, Greenberg, Gélisse, Hadidi, Hertzog, Hraiech, Hynynen, Johnston, Kawada, Kim, Koster, Krueger, Lamarche, Latronico, Lemaitre, Levison, Malfertheiner, Mehta, Michelle Peahota, Moore, Mousavi, Mulla, Mulla, Muntean, Oliver, Paden, Park, Perkins, Peters, Pettignano, Phillips, Pieri, Potter, Preston, Protti, Ranucci, Riker, Roberts, Roos, Rosen, Ruiz, Rybak, Saini, Sanfilippo, Satyapriya, Schmith, Shekar, Shekar, Shekar, Shekar, Shekar, Sherwin, Sklar, Smith, Spriet, Staudacher, Strunk, Subramaniam, Szefner, Tellor, Trudzinski, Tulman, Turner, Veinstein, Vilay, Wagner, Walter K. Kraft, Welsch, Wen, Wildschut, Wu, Young   +99 more
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Pharmacokinetic/pharmacodynamic modelling approaches in paediatric infectious diseases and immunology. [PDF]

, 2014
Pharmacokinetic/pharmacodynamic (PKPD) modelling is used to describe and quantify dose-concentration-effect relationships. Within paediatric studies in infectious diseases and immunology these methods are often applied to developing guidance on ...
Abdel-Rahman, Ahsman, Ambrose, Anderson, Anderson, Anderson, Andes, Andes, Assael, Baley, Barclay, Barclay, Barlogis, Bartelink, Bayles, Benjamin, Benson, Berger, Bhandari, Blumer, Bomgaars, Bonate, Botha, Bouazza, Bradley, Buck, Burkhardt, Call, Charles, Charlotte I.S. Barker, Charrier, Chen, Clave, Cohen-Wolkowiez, Cohen-Wolkowiez, Committee, Craig, De Beaudrap, de Groot, de Hoog, de Hoog, de Hoog, de Repentigny, Doby, Doogue, Dowell, Downing, Driscoll, Driscoll, Drusano, Drylewicz, Du, Dudley, Duval, Elter, Englund, Ette, Ette, Ette, Eva Germovsek, Fallen, Fedele, Filler, Fletcher, Foot, Forrest, Frenkel, Friberg, Garcia, Garrido, Giannelli, Giuliano, Glowka, Gonzalez-Peralta, Grimsley, Groll, Groll, Guedj, Hassan, Hennig, Herbrecht, Hintz, Hong, Hope, Hope, Hope, Hope, Hosoya, Huenecke, Iida, Ikawa, Izquierdo, Jacqz-Aigrain, Jensen, Joanna Lewis, Jodi M. Lestner, Joseph F. Standing, Kafetzis, Karlsson, Kaufman, Kearns, Kelley, Kicklighter, Kim, Kimberlin, Kimberlin, Kimberlin, Knoderer, Koehl, Koenig, Kohli, Krakovska, Krishna, Lam, Lankester, Lavielle, Lee, Lee, Lestner, Lewis, Lewis, Lewis, Li, Li, Lodise, Louie, Luck, Lukas, Marques-Minana, McJunkin, Meszner, Mohamed, Moore, Muller, Muller, Neely, Neely, Nielsen, Ogungbenro, Ohata, Olkinuora, Oxford, Padari, Palumbo, Parker, Pascual, Payen, Perelson, Pescovitz, Pescovitz, Piper, Plunkett, Prague, Preston, Pullen, Putter, Rajagopalan, Renard, Rodriguez, Rodriguez-Tudela, Rollo L. Hoare, Rong, Rudd, Sabin, Saez-Llorens, Saez-Llorens, Salinger, Sardemann, Saxen, Schaefer, Schmitt, Schwinger, Seibel, Seidel, Sherwin, Smith, Standing, Starke, Sugaya, Sullender, Surh, Suyagh, Tamma, Tarral, Tasso, Tedeschi, Terragna, Thiebaut, Thiébaut R, Tod, Tod, Touw, Tulkens, van den Anker, van Hasselt, Vandecasteele, Vaudry, Vervelde, Vezina, Walsh, Waxman, Willemze, Wu, Wurthwein, Yoshizawa, Zeng, Zhang, Zhao, Zobell   +208 more
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Pharmacokinetic Herb-Drug Interactions: Insight into Mechanisms and Consequences [PDF]

, 2015
Herbal medicines are currently in high demand, and their popularity is steadily increasing. Because of their perceived effectiveness, fewer side effects and relatively low cost, they are being used for the management of numerous medical conditions ...
Horie, Toshiharu, Oga, Enoche Florence, Sekine, Shuichi, Shitara, Yoshihisa   +3 more
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The pharmacokinetics of nebulized nanocrystal budesonide suspension in healthy volunteers. [PDF]

, 2004
Nanocrystal budesonide (nanobudesonide) is a suspension for nebulization in patients with steroid-responsive pulmonary diseases such as asthma. The pharmacokinetics and safety of the product were compared to those of Pulmicort Respules.
Beussink, Don, Fitzgerald, Nancy, Greenberg, Howard E., Kraft, Walter, Quiring, John N., Steiger, Barry, Waldman, Scott A.   +6 more
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Role of therapeutic drug monitoring in pulmonary infections : use and potential for expanded use of dried blood spot samples [PDF]

, 2015
Respiratory tract infections are among the most common infections in men. We reviewed literature to document their pharmacological treatments, and the extent to which therapeutic drug monitoring (TDM) is needed during treatment.
Akkerman, Onno W, Alffenaar, Jan-Willem C, Bolhuis, Mathieu S, Hofman, Susan, Koster, Remco A, Stove, Christophe, van Assen, Sander   +6 more
core   +2 more sources