Results 71 to 80 of about 680,797 (315)

Role of Fe/Co Ratio in Dual Phase Ce0.8gd0.2o2− Δ –Fe3-Xcoxo4 Composites for Oxygen Separation

, 2023
Liudmila Fischer, Ke Ran, Christina Schmidt, Kerstin Neuhaus, Joachim Mayer, Patrick Behr, H.J.M. Bouwmeester, Arian Nijmeijer, Stefan Baumann, W.A. Meulenberg   +9 more
openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

ricePSP: a database of rice phase separation-associated proteins

Genome Biology
Multivalent interactions between proteins with intrinsically disordered regions or prion-like domains can drive liquid–liquid phase separation (LLPS) and form membraneless condensates essential for diverse cellular functions.
Runxin Gao, Minrong Guo, Shiping Luan, Weizhi Ouyang, Xingwang Li   +4 more
doaj   +1 more source

Review for "Partial structure factors derived from coarse-grained phase-separation dynamics on a disordered lattice with density fluctuations"

, 2021
Michele Burrello
openalex   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Decision letter: DNA-Stimulated Liquid-Liquid phase separation by eukaryotic topoisomerase ii modulates catalytic function

, 2022
Nancy Kleckner
openalex   +1 more source

Viscoelastic model of phase separation [PDF]

Physical Review E, 1997
We show here a general model of phase separation in isotropic condensed matter, namely, a viscoelastic model. We propose that the bulk mechanical relaxation modulus that has so far been ignored in previous theories plays an important role in viscoelastic phase separation in addition to the shear relaxation modulus.
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

HP1 loses its chromatin clustering and phase separation function across evolution

Nature Communications
Heterochromatin protein 1 (HP1) is a multifunctional chromatin-associated protein conserved from fission yeast to mammals. HP1 has been suggested to drive heterochromatin formation via phase separation.
Sanâa Bensaha, Dominika Lewandowska, Fernando Muzzopappa, Stephanie Hutin, Mark D. Tully, Michela Anfossi, Florence M. Cammas, Christophe Normand, Fabian Erdel   +8 more
doaj   +1 more source