Results 91 to 100 of about 5,655,447 (304)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Phase Separation on a Hyperbolic Lattice

open access: yesPhysics Procedia, 2014
We report a preliminary numerical study by kinetic Monte Carlo simulation of the dynamics of phase separation following a quench from high to low temperature in a system with a single, conserved, scalar order parameter (a kinetic Ising ferromagnet) confined to a hyperbolic lattice.
Raffeld, Jesse   +3 more
openaire   +2 more sources

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Phase separation in the spherical model

open access: yesJournal of Physics A: Mathematical and General, 1979
The spherical model in an inhomogeneous external field is investigated. It is shown that whenever there is a phase transition the phases do not separate. This, together with decoupling effects in the magnetisation profile as well as in the transverse correlation functions, suggests abnormally large fluctuations and strong field dependence.
Abraham, D, Robert, M
openaire   +1 more source

ricePSP: a database of rice phase separation-associated proteins

open access: yesGenome Biology
Multivalent interactions between proteins with intrinsically disordered regions or prion-like domains can drive liquid–liquid phase separation (LLPS) and form membraneless condensates essential for diverse cellular functions.
Runxin Gao   +4 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Thermal behaviour of zircon/zirconia-added chemically durable borosilicate porous glass [PDF]

open access: yes, 2013
Macroporous alkali resistant glass has been developed by making additions of zirconia (ZrO2) and zircon (ZrSiO4) to the sodium borosilicate glass system SiO2–B2O3 Na2O. The glass was made using a traditional high temperature fusion process.
Olabi, Abdul-Ghani   +4 more
core   +2 more sources

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

A novel ionic-bonded cellulose stationary phase for saccharide separation

open access: yes, 2013
A hydrophilic interaction liquid chromatography (HILIC) stationary phase of cellulose-coated silica was synthesized as a novel saccharide separation material.
Sheng, Qianying   +6 more
core   +1 more source

Liquid–liquid phase separation in diseases

open access: yesMedComm
Liquid–liquid phase separation (LLPS), an emerging biophysical phenomenon, can sequester molecules to implement physiological and pathological functions.
Xinyue Zhang   +7 more
doaj   +1 more source

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