Results 91 to 100 of about 753,839 (313)

Reversed-Phase-Reversed-Phase Liquid Chromatography Approach with High Orthogonality for Multidimensional Separation of Phosphopeptides [PDF]

, 2010
Protein phosphorylation regulates a series of important biological processes in eukaryotes. However, the phosphorylation sites found up to now are far below than that actually exists in proteins due to the extreme complexity of the proteome sample.
Song, Chunxia, Yu, Zhiyuan, Wang, Fangjun, Jiang, Xinning, Han, Guanghui, Zou, Hanfa, 邹汉法, Ye, Mingliang, Chen, Rui   +8 more
core   +1 more source

Effect of clay materials on phase separation in plastic bag waste-modified bitumen during high-temperature storage

Transportation Engineering
Phase separation at high storage temperatures is a significant challenge in the practical application of polymer-modified bitumen (PmB), as it impacts negatively the uniformity and stability of modified binders.
Mohammed Nouali, Zohra Derriche, Elhem Ghorbel   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Editorial: Biological Phase Separation

Frontiers in Genetics, 2022
Eiichiro Mori, Tony Z. Jia, Tony Z. Jia
doaj   +1 more source

Phase separation of biomembrane-polyelectrolyte interaction system

Shenzhen Daxue xuebao. Ligong ban
This study models the regulatory process of biomacromolecular phase separation facilitated by biological membranes. Utilizing molecular dynamics simulations based on the coarse graining (CG) Martini force field, we investigate the phase separation of ...
HAN Tuodi, GUO Xiuzhen, ZHAO Xinjun, WU Xiaoting   +3 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Separation and purification of hydrolyzable tannin from Geranium wilfordii Maxim by reversed-phase and normal-phase highspeed counter-current chromatography [PDF]

, 2010
Three hydrolyzable tannins, geraniin, corilagin and gallic acid, main active components of Geranium wilfordii Maxim, have been separated and purified in one-step by both reversed-phase and normal-phase high-speed counter-current chromatography.
Wang, Changhai, Gu, M, Su, Zhiguo, Gu, Ming, Liu, Dan, Xing, Siliang   +5 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source