Results 81 to 90 of about 5,655,447 (304)

Effect of clay materials on phase separation in plastic bag waste-modified bitumen during high-temperature storage

open access: yesTransportation Engineering
Phase separation at high storage temperatures is a significant challenge in the practical application of polymer-modified bitumen (PmB), as it impacts negatively the uniformity and stability of modified binders.
Mohammed Nouali   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Editorial: Biological Phase Separation

open access: yesFrontiers in Genetics, 2022
Eiichiro Mori, Tony Z. Jia, Tony Z. Jia
doaj   +1 more source

Phase Separation in Doped Mott Insulators

open access: yesPhysical Review X, 2015
Motivated by the commonplace observation of Mott insulators away from integer filling, we construct a simple thermodynamic argument for phase separation in first-order doping-driven Mott transitions.
Chuck-Hou Yee, Leon Balents
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Phase separation of biomembrane-polyelectrolyte interaction system

open access: yesShenzhen Daxue xuebao. Ligong ban
This study models the regulatory process of biomacromolecular phase separation facilitated by biological membranes. Utilizing molecular dynamics simulations based on the coarse graining (CG) Martini force field, we investigate the phase separation of ...
HAN Tuodi   +3 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Viscoelastic model of phase separation [PDF]

open access: yesPhysical Review E, 1997
We show here a general model of phase separation in isotropic condensed matter, namely, a viscoelastic model. We propose that the bulk mechanical relaxation modulus that has so far been ignored in previous theories plays an important role in viscoelastic phase separation in addition to the shear relaxation modulus.
openaire   +2 more sources

Phase separation and mechanical properties of epoxy / thermoplastic blends [PDF]

open access: yes, 2003
Thermosetting epoxy resins blended with aromatic thermoplastics are of significant commercial interest in several areas including aerospace, transportation and electronics.
Emmerson, Gordon T., Emmerson, Gordon T
core  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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