Results 111 to 120 of about 753,839 (313)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Numerical analysis of a coupled pair of Cahn-Hilliard equations [PDF]

open access: yes, 2001
A mathematical analysis has been carried out for a coupled pair of Cahn-Hilliard equations, which appear in modelling a phase separation on a thin film of binary liquid mixture coating substrate, which is wet by one component.
Imran, M., Imran M.,
core  

Synthesis of a stationary phase based on silica modified with branched octadecyl groups by Michael addition and photoinduced thiol-yne click chemistry for the separation of basic compounds [PDF]

open access: yes, 2016
A novel silica-based stationary phase with branched octadecyl groups was prepared by the sequential employment of the Michael addition reaction and photoinduced thiol-yne click chemistry with 3-aminopropyl-functionalized silicamicrospheres as the ...
Zou, Hanfa   +7 more
core   +1 more source

Phase Separation Regulates Metabolism, Mitochondria, and Diseases

open access: yesMedComm
As a physicochemical mechanism, phase separation is a spatial and temporal regulator of specific molecules within a cell, and it provides a new perspective for understanding cellular pathophysiology.
Chuan Gao   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Cluster-liquid phase separation in cluster decay

open access: yesPhysics Letters B
In cluster decay, a heavy nucleus spontaneously emits a light nucleus, leaving a daughter nucleus in the neighborhood of the double-magic 208Pb. The two fragments exhibit extreme mass asymmetry and possess completely distinct properties, including ...
Yinu Zhang   +3 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Evaluation and Application of Stationary Phase Selectivity for Drug Analysis [PDF]

open access: yes
Despite the wide range of HPLC stationary phases available for reversed-phase high-performance liquid chromatography (RP-HPLC) and the in-depth studies using probes to highlight differences between them, there is very little in the way of stationary ...
Perera, R. Wimal H.
core  

Higher-order anisotropic models in phase separation

open access: yesAdvances in Nonlinear Analysis, 2017
Our aim in this paper is to study higher-order (in space) Allen–Cahn and Cahn–Hilliard models. In particular, we obtain well-posedness results, as well as the existence of the global attractor.
Cherfils Laurence   +2 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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