Results 131 to 140 of about 680,797 (315)

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Influence of nanovoids on α–α′ phase separation in FeCrAl oxide dispersion strengthened alloy

, 2015
C. Capdevila, M. M. Aranda, Rosalía Rementeria, R. Domínguez-Reyes, Esteban Urones‐Garrote, M.K. Miller   +5 more
openalex   +2 more sources

Mechanical properties and fracture behaviors of epoxy composites with phase‐separation formed liquid rubber and preformed powdered rubber nanoparticles: A comparative study [PDF]

, 2014
Li Guan, Li‐Xiu Gong, Long‐Cheng Tang, Lianbin Wu, Jianxiong Jiang, Guo‐Qiao Lai   +5 more
openalex   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Phase Separation and Properties of UV‐Curable Polyurethane/Zirconia Nanocomposite Coatings [PDF]

, 2008
Shuxue Zhou, Limin Wu
openalex   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Liquid-liquid phase separation in neural development. [PDF]

Cell Mol Life Sci
Surini S, de Curtis I.
europepmc   +1 more source

β-Detected NMR Search for Magnetic Phase Separation in Epitaxial GaAs:Mn

, 2012
Qinghai Song, K. H. Chow, R. I. Miller, I. Fan, M. D. Hossain, R. F. Kiefl, G. D. Morris, S. R. Kreitzman, C.D.P. Levy, T.J. Parolin, M. R. Pearson, Z. Salman, H. Saadaoui, M. Smadella, D. Wang, K. M. Yu, Xiao Liu, J. K. Furdyna, W. A. MacFarlane   +18 more
openalex   +1 more source

Optical and structural investigations of annealing impact on phase separation of Erbium-doped Al2O3 layers

, 2023
Nissrine Al Helou, L. Khomenkova, E. Cadel, Christophe Labbé, Julien Cardin, F. Gourbilleau, Etienne Talbot   +6 more
openalex   +2 more sources

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source