Results 121 to 130 of about 753,839 (313)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Laser-induced phase separation of silicon carbide
Nature Communications, 2016 Laser beam-induced processing is industrially relevant but often challenging to study in terms of underlying phase transformations. Here authors characterize formation of thin, phase-separated carbon and silicon layers on a silicon carbide substrate by ...
Insung Choi +10 more
doaj +1 more source
Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach
FEBS Letters, EarlyView.The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Nylon-6 membranes with combined crystalline and liquid-liquid phase separation morphologies [PDF]
, 2013 Aliphatic polyamide, nylon-6, membranes were prepared by isothermal immersion-precipitation from formic acid solutions in an aqueous non-solvent bath. Depending on the composition of the polymer solution and the non-solvent bath, phase transformation can
Cheng, Liao-ping
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Phase separation on ricinoleic acid freezing
MATEC Web of Conferences, 2018 Phase separation material essentially influence storage capacity or heat release. Ricinoleic acid is potential to be used as a heat storage material. However, the nature of the phase separation of the material has not been studied yet.
Firman, Hasan Barlian, Anshar Muhammad
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Liquid–liquid phase separation in diseases
MedCommLiquid–liquid phase separation (LLPS), an emerging biophysical phenomenon, can sequester molecules to implement physiological and pathological functions.
Xinyue Zhang +7 more
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Application of La_2O_3-TiO_2 Porous Glass-Ceramic System to a Humidity Sensor [PDF]
, 1987 The sodium borate glass system containing La2O3 and TiO2 shows a marked trend toward microphase separation after heat treatment, resulting in water-soluble sodium borate and water-insoluble La2O3-TiO2 ceramic phases.
清水, 康博 +2 more
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