Results 121 to 130 of about 7,348,255 (319)
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
The distribution of stress singularity field near the vertex of two-phase material components is very important to maintain the reliability of intelligent materials.
Islam, Md. Shahidul +2 more
core +1 more source
Detection of small cancer biomarkers with low molecular weight and a low concentration range has always been challenging yet urgent in many clinical applications such as diagnosing early-stage cancer, monitoring treatment and detecting relapse.
Jean-Christophe Orlianges (17521206) +13 more
core +1 more source
Viscosity in Modified Gravity 
A bulk viscosity is introduced in the formalism of modified gravity. It is shownthat, based on a natural scaling law for the viscosity, a simple solution can be found forquantities such as the Hubble parameter and the energy density.
Iver Brevik
doaj +1 more source
Highly Sensitive Plasmonic Waveguide Biosensor Based on Phase Singularity-Enhanced Goos-Hänchen Shift. [PDF]
Hedhly M +5 more
europepmc +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Disorder‐Induced Quantum Griffiths Singularity Revealed in an Artificial 2D Superconducting System
Disorder‐induced Griffiths singularity of quantum phase transition (QPT) is a crucial issue in 2D superconductors (2DSC). In a superconducting system, the strength of disorder is found to be associated with the vortex pinning energy, which is closely ...
Xiaowen Han +9 more
doaj +1 more source
Phase Transformation and Singularity Theory [PDF]
AbstractPhase transformation plays an important role in thermodynamics and materials science. Based on the theory of singularities, a new method to construct phase diagrams is presented. Analysing singularities on base of root sequences, see Tamaschke [16], will help to develop singularity graphs, where workings by H. Whitney, R. Thom, and V. I. Arnold
openaire +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Phase singularity and delinquent teenager
У цьому дослідженні виділено період фазової сингулярності для средньогрупового делінквентного підлітка, позначено статеву диференціацію і систематизовано кількісні дані скоєних правопорушень у підлітковому віці.
Коваль, Анна Шамильевна +2 more
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