Results 91 to 100 of about 84,152 (313)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Revisiting metastable cosmic string breaking

Journal of High Energy Physics
Metastable cosmic strings appear in models of new physics with a two-step symmetry breaking G → H → 1, where π 1(H) ≠ 0 and π 1(G) = 0. They decay via the monopole-antimonopole pair creation inside. Conventionally, the breaking rate has been estimated by
Akifumi Chitose, Masahiro Ibe, Yuhei Nakayama, Satoshi Shirai, Keiichi Watanabe   +4 more
doaj   +1 more source

Primordial gravitational wave backgrounds from phase transitions with next generation ground based detectors [PDF]

Classical and quantum gravity
Third generation ground-based gravitational wave (GW) detectors, such as Einstein Telescope and Cosmic Explorer, will operate in the (few−104) Hz frequency band, with a boost in sensitivity providing an unprecedented reach into primordial cosmology ...
C. Caprini, O. Pujolàs, H. Quelquejay-Leclere, Fabrizio Rompineve, D. Steer   +4 more
semanticscholar   +1 more source

The First Magnetic Fields

, 2011
We review current ideas on the origin of galactic and extragalactic magnetic fields. We begin by summarizing observations of magnetic fields at cosmological redshifts and on cosmological scales.
A. Brandenburg, A. Kosowsky, A. Lazarian, A. Lewis, A. Mack, A. Neronov, A. Rebhan, A. Yahil, A.A. Starobinskii, A.H. Guth, A.J. Keane, B. Cheng, B. Himmetoglu, B. Himmetoglu, B. Ratra, B. Schenke, B.D. Fried, C. Bonvin, C. Caprini, C. Pinto, C. Pinto, C.D. Dermer, C.G. Tsagas, C.G. Tsagas, C.G. Tsagas, C.J. Hogan, C.L. Carilli, Christos G. Tsagas, D. Grasso, D.G. Yamazaki, D.H. Lyth, D.R.G. Schleicher, D.R.G. Schleicher, D.R.G. Schleicher, D.T. Son, Dominik R. G. Schleicher, Dongsu Ryu, E. Fenu, E. Weibel, E.-J. Kim, E.W. Kolb, F. Finelli, F. Hoyle, F. Hoyle, G. Davies, G. Sigl, G.B. Field, H. Maki, H. Stefani, H. Tashiro, H. Tashiro, H. Xu, I. Brown, J. Adamek, J. Adams, J. Martin, J. Silk, J. Silk, J.-P. Blaizot, J.A. Peacock, J.A. Quashnock, J.C. Tan, J.D. Barrow, J.D. Barrow, J.D. Barrow, J.D. Jackson, J.M. Cornwall, J.R. Shaw, K. Ichiki, K. Jedamzik, K. Jedamzik, K. Subramanian, K. Subramanian, K. Subramanian, K. Subramanian, K. Subramanian, K. Subramanian, K. Subramanian, K. Takahashi, K. Thorne, K.-T. Kim, Kandaswamy Subramanian, L. Biermann, L.F.S. Rodrigues, L.M. Widrow, Lawrence M. Widrow, M. Ando, M. Christensson, M. Gasperini, M. Giovannini, M. Langer, M. Strickland, M. Strickland, M.A. Stenrup, M.J. Rees, M.J. Rees, M.L. Bernet, M.N. Machida, M.S. Turner, M.V. Penston, N.Y. Gnedin, P. Anninos, P. Arnold, P. Arnold, P. Arnold, P. Arnold, P. Arnold, P. Hennebelle, P. Hennebelle, P. Romatschke, P.J. Greenberg, P.J.E. Peebles, P.J.E. Peebles, P.P. Kronberg, P.P. Kronberg, P.P. Kronberg, R. Banerjee, R. Banerjee, R. Banerjee, R. Durrer, R. Durrer, R. Durrer, R. Durrer, R.-G. Cai, R.A. Daly, R.B. Larson, R.E. Pudritz, R.M. Athreya, R.M. Kulsrud, R.M. Kulsrud, Rudolf A. Treumann, S. Bethke, S. Seager, S. Sur, S.C.O. Glover, S.D.M. White, S.I. Syrovatskii, S.K. Sethi, S.W. Hawking, St. Mrówczyński, St. Mrówczyński, T. Abel, T. Abel, T. Kahniashvili, T. Vachaspati, T.R. Seshadri, T.R. Seshadri, U. Frisch, V. Bromm, V. Demozzi, Ya.B. Zel’dovich, Yu.E. Pokrovsky   +151 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Probing early Universe supercooled phase transitions with gravitational wave data [PDF]

, 2023
C. Badger, Bartosz Fornal, K. Martinovic, A. Romero, K. Turbang, Huai-Ke Guo, Alberto Mariotti, Mairi Sakellariadou, Alexander Sevrin, F. W. Yang, Yue Zhao   +10 more
openalex   +1 more source

Constraining the impact of standard model phase transitions on primordial black holes [PDF]

Journal of Cosmology and Astroparticle Physics
Phase transitions in the early universe lead to a reduction in the equation of state of the primordial plasma. This exponentially enhances the formation rate of primordial black holes.
Xavier Pritchard, C. Byrnes
semanticscholar   +1 more source

Hearing the echoes of electroweak baryogenesis with gravitational wave detectors

, 2016
We report on the first joint analysis of observational signatures from the electroweak baryogenesis in both gravitational wave (GW) detectors and particle colliders.
Cai, Yi-Fu, Huang, Fa Peng, Wan, Youping, Wang, Dong-Gang, Zhang, Xinmin   +4 more
core   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source

Spinning primordial black holes from first order phase transition

Journal of High Energy Physics
We conduct a novel study to obtain the initial spin of the primordial black holes created during a first-order phase transition due to delayed false vacuum decay.
Indra Kumar Banerjee, Ujjal Kumar Dey
doaj   +1 more source