Results 81 to 90 of about 149,223,535 (289)
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Phase transitions in project scheduling. [PDF]
The analysis of the complexity of combinatorial optimization problems has led to the distinction between problems which are solvable in a polynomially bounded amount of time (classified in P) and problems which are not (classified in NP).
De Reyck, B, Herroelen, Willy
core
Walls, bubbles and doom — the cosmology of HEFT
Journal of High Energy PhysicsAs experiment charts new territory at the electroweak scale, the enterprise to characterise all possible theories becomes all the more necessary. In the absence of new particles, this ambitious enterprise is attainable and has led to the Higgs Effective ...
R. Alonso +3 more
doaj +1 more source
Supercooled phase transitions in the very early universe
Physics Letters B, 1982 The universe might have had a prolonged exponentially expanding phase caused by its being stuck in a metastable state of the grand unified phase transition. The only way that it could exit from this exponential expansion without introducing too much inhomogeneity or spatial curvature would be through a homogeneous “bubble” solution in which quantum ...
S.W. Hawking, I.L. Moss
openaire +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Phase transitions in the early and the present Universe
, 2006 41 pages, 16 figures, to appear in Ann. Rev. Nucl. Part. Sci 2006. Presentation improved, references addedInternational audienceThe evolution of the Universe is the ultimate laboratory to study fundamental physics across energy scales that span about 25 ...
Schwarz, D. J. +2 more
core
Bubble nucleation from boson star collapse
Journal of High Energy PhysicsWe present a new classical mechanism for nucleation of bubbles of true vacuum. The mechanism arises when dense boson stars form in the false vacuum.
Aleksandr Azatov +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Revisiting metastable cosmic string breaking
Journal of High Energy PhysicsMetastable cosmic strings appear in models of new physics with a two-step symmetry breaking G → H → 1, where π 1(H) ≠ 0 and π 1(G) = 0. They decay via the monopole-antimonopole pair creation inside. Conventionally, the breaking rate has been estimated by
Akifumi Chitose +4 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source