Results 161 to 170 of about 6,861,845 (296)
‘Guide and Prejudice’— How Argonautes recognize targets across domains of life
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley +1 more source
Linguistic Variation and Change
A comprehensive study of variation and change, including current debates in the area.Intro -- Cover -- Copyright -- Contents -- Figures -- Tables -- Preface and acknowledgements -- Terminology and notation conventions -- Phonetic notation -- Part I ...
Kiesling, Scott F.
core
Structural and biochemical analysis of a B12 superbinder
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Estimating the phase congruency of localised frequencies
Phase congruency is a new method for detecting features in images. One of its significant strengths is its invariance to lighting variation within an image, as well as being able to detect a wide range of interesting features.
Myerscough, Peter J, Nixon, Mark S
core +1 more source
Epigenetic phase variation in the gut microbiome enhances bacterial adaptation. [PDF]
Ni M +14 more
europepmc +1 more source
How does feedback from phage infections influence the evolution of phase variation in Campylobacter? [PDF]
Sandhu SK, Bayliss CD, Morozov AY.
europepmc +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
What goes around comes around: updates in the study of <i>Coxiella burnetii</i> lipopolysaccharide phase variation. [PDF]
Pierce KN +4 more
europepmc +1 more source
Effects of Age, Phase Variation and Pheromones on Male Sperm Storage in the Desert Locust, Schistocerca gregaria. [PDF]
Hiroyoshi S +3 more
europepmc +1 more source
Analysing Variation in English
This book brings together a range of perspectives on the collection, analysis and broader relevance of variable language data.Cover -- Half-title -- Title -- Copyright -- Contents -- Figures -- Tables -- Contributors -- Abbreviations -- Corpora and tools
McMahon, April., Maguire, Warren.
core

