Results 11 to 20 of about 1,044 (124)

Pyrrolo-Fused Phenanthridines as Potential Anticancer Agents: Synthesis, Prediction, and Biological Evaluation. [PDF]

J Biochem Mol Toxicol
ABSTRACT We report the synthesis of four novel monoquaternary salts and four fused pyrrolo‐phenanthridine compounds, fully characterized by NMR, FT‐IR, and mass spectrometry. Guided by theoretical predictions, including molecular docking studies, we assessed their cytotoxic activity and biocompatibility.
Al-Matarneh A, Simionescu N, Nicolescu A, Cibotariu N, Danac R, Al-Matarneh MC, Mangalagiu II.   +6 more
europepmc   +2 more sources

Fluorescent Carbazole-Derived Aza[5]Helicenes: Synthesis, Functionalization, and Characterization. [PDF]

Chemistry
Variously substituted indolophenanthridines, indolocarbazoles, and cinnolinocarbazoles synthesized by ortho fusion from teraryl precursors show significant Stokes shifts, especially for the protonated states of indolophenanthridines and cinnolinocarbazole.
Marten I, Dilanas MEA, Podlech J.
europepmc   +2 more sources

Dichloridobis(phenanthridine-κN)zinc(II) [PDF]

Acta Crystallographica Section E Structure Reports Online, 2009
In the mol-ecule of the title compound, [ZnCl(2)(C(13)H(9)N)(2)], the Zn(II) atom is four-coordinated in a distorted tetra-hedral configuration by two N atoms from two phenanthridine ligands and by two terminal Cl atoms. The dihedral angle between the planes of the phenanthridine ring systems is 69.92 (3)°.
Khoshtarkib, Zeinab, Ebadi, Amin, Alizadeh, Robabeh, Ahmadi, Roya, Amani, Vahid   +4 more
openaire   +2 more sources

Metal-Free Photoredox Catalyzed Cyclization of O-(2,4-Dinitrophenyl)oximes to Phenanthridines

Molecules, 2016
A metal-free visible-light photoredox-catalyzed intermolecular cyclization reaction of O-2,4-dinitrophenyl oximes to phenanthridines was developed. In this study, the organic dye eosin Y and i-Pr2NEt were used as photocatalyst and terminal reductant ...
Xiubin Liu, Zhixing Qing, Pi Cheng, Xinyu Zheng, Jianguo Zeng, Hongqi Xie   +5 more
doaj   +1 more source

In Pursuit of Low Energy Phosphorescence: Late Metal Coordination Complexes of the Planar, π-extended Bipyridyl Ligand 6,6',7,7'-Biphenanthridine. [PDF]

Chemistry
Abstract The coordination chemistry of the planar, doubly π‐extended bipyridine analog, 6,6′,7,7′‐biphenanthridine (p‐biphe), is presented. The phenanthridine units in p‐biphe are fused together at the 6‐ and 7‐ positions, and the resulting rigid ligand is compared with the more flexible parent “biphe” fused only at the 6‐positions.
Nemez DB, Ortiz RJ, Veilleux KA, Williams JAG, Herbert DE.   +4 more
europepmc   +2 more sources

From Isocyanides to Iminonitriles via Silver-mediated Sequential Insertion of C(sp3)–H Bond

iScience, 2019
Summary: Heterocycles are prevalent constituents of many marketing drugs and biologically active molecules to meet modern medical challenges. Isocyanide insertion into C(sp3)–H bonds is challenging especially for the construction of quaternary carbon ...
Huiwen Chi, Hao Li, Bingxin Liu, Rongxuan Ye, Haoyang Wang, Yin-Long Guo, Qitao Tan, Bin Xu   +7 more
doaj   +1 more source

Synthesis of phenanthridines via palladium-catalyzed picolinamide-directed sequential C–H functionalization

Beilstein Journal of Organic Chemistry, 2013
We report a new synthesis of phenanthridines based on palladium-catalyzed picolinamide-directed sequential C–H functionalization reactions starting from readily available benzylamine and aryl iodide precursors.
Ryan Pearson, Shuyu Zhang, Gang He, Nicola Edwards, Gong Chen   +4 more
doaj   +1 more source

The phytogenic feed additive Sangrovit modulates dextran sulfate sodium-induced colitis in rats

Veterinární Medicína, 2010
The alkaloids of Macleaya cordata (Papaveracae) are active components of the phytogenic feed additive Sangrovit. The present study was conducted to evaluate the effects of Sangrovit on dextran sulfate sodium (DSS)-induced colitis using rats as an ...
E. Vrublova, J. Vostalova, J. Ehrmann, I. Palikova, J. Vrbkova, J. Vacek, N. Cibicek, R. Vecera, J. Ulrichova, V. Simanek   +9 more
doaj   +1 more source

Synthesis and Characterization of Carbazole‐Containing Aza[7]helicenes

Chemistry – A European Journal, EarlyView.
Double ortho fusion led to different aza[7]helicene frameworks showing strong acidochromic behavior, singlet excited energies being more than twice the triplet energy, and high racemization barriers, allowing chiral resolution and ECD measurements. ABSTRACT Azahelicenes have attracted significant interest due to their intrinsic axial chirality and ...
Inka Marten, Melina E. A. Dilanas, Joachim Podlech   +2 more
wiley   +1 more source

Quantitative Correlation Between Charge Transfer and Two Photon Absorption in Phenanthridine‐TCNB Cocrystal

Information &Functional Materials, EarlyView.
A new molecular cocrystal shows D‐A alternative molecular stacking, cyan‐blue photoluminescence with lifetime of 19.76 ns, and two‐photon absorption enabled emission under laser excitation between 720 and 880 nm. Theoretical calculations reveal its static dipole moment of 2.84 D, CT character in the ground, S1, and S2 excited states, and the TPA ...
Weigang Zhu, Ying Ni, Bin Li, Rafael C. González‐Cano, Wenping Hu   +4 more
wiley   +1 more source