Analysis of benzo[c] phenanthridine alkaloids in Eschscholtzia californica cell culture using HPLC-DAD and HPLC-ESI-MS/MS [PDF]
Effective HPLC-DAD and HPLC-ESI-MS/MS methods have been developed for the analysis of eight benzo[c] phenanthridine alkaloids (sanguinarine, chelirubine, macarpine, chelerythrine, dihydrosanguinarine, dihydrochelirubine, dihydromacarpine and ...
Hong Soon Rhee +4 more
core +1 more source
From Isocyanides to Iminonitriles via Silver-mediated Sequential Insertion of C(sp3)–H Bond
Summary: Heterocycles are prevalent constituents of many marketing drugs and biologically active molecules to meet modern medical challenges. Isocyanide insertion into C(sp3)–H bonds is challenging especially for the construction of quaternary carbon ...
Huiwen Chi +7 more
doaj +1 more source
Stochastic models (cooperative and non-cooperative) for NMR analysis of the hetero-association of aromatic molecules in aqueous solution [PDF]
Stochastic cooperative (STOCH-C) and non-cooperative (STOCH-NC) models have been developed for NMR analysis of the hetero-association of aromatic compounds in solution, in order to take into account all physically meaningful association reactions of ...
Davies, David B. +2 more
core +1 more source
1H NMR determination of the self-association of an acridine homodimer and its complexation with ethidium bromide in aqueous solution [PDF]
1H NMR spectroscopy (500MHz) has been used to investigate the self-association in aqueous buffered solution of a bis-intercalator, Acridine Homodimer (AcrH), and its hetero-association with the aromatic dye, Ethidium Bromide (EB).
Barbet +22 more
core +1 more source
Paradoxical effects of the topoisomerase inhibitor, ethoxidine, in the cellular processes leading to angiogenesis on EaHy.926 endothelial cells [PDF]
Topoisomerase I generates transient single-stranded breaks in DNA and have the capacity to fragment the genome. Thus, this enzyme is the target for some of the most successful anticancer drugs.
J.J. Helesbeux +4 more
core +2 more sources
Comparing the rate of growth and metabolic efficiency of yeast experiencing environmental stress or genetic damage [PDF]
Physical stresses, toxic substances, and mutations can cause marked decline in the rate of growth (RG). We report that the efficiency of growth (EG), i.e. converting glucose into biomass, responds less profoundly.
Jakubowska, Agata +2 more
core +1 more source
The phytogenic feed additive Sangrovit modulates dextran sulfate sodium-induced colitis in rats
The alkaloids of Macleaya cordata (Papaveracae) are active components of the phytogenic feed additive Sangrovit. The present study was conducted to evaluate the effects of Sangrovit on dextran sulfate sodium (DSS)-induced colitis using rats as an ...
E. Vrublova +9 more
doaj +1 more source
SYNTHESIS OF ZANTHOXYLINE AND ITS RELATED COMPOUNDS: REVISION OF THE REPORTED STRUCTURE [PDF]
Benzo[c]phenanthridine alkaloid, zanthoxyline, was synthesized through an intramolecular biaryl coupling reaction of N-naphthylbenzamide derivative using a palladium reagent.
Abe Hitoshi +4 more
core +3 more sources
Mo–Catalyzed One-Pot Synthesis of N-Polyheterocycles from Nitroarenes and Glycols with Recycling of the Waste Reduction Byproduct. Substituent-Tuned Photophysical Properties [PDF]
A catalytic domino reduction–imine formation– intramolecular cyclization–oxidation for the general synthesis of a wide variety of biologically relevant N-polyheterocycles, such as quinoxaline- and quinoline-fused derivatives, and phenanthridines, is ...
Fernández Rodríguez, Manuel A. +6 more
core +1 more source
Nitrogen‐Centered Organic Persistent Radicals Catalyze Redox‐Neutral C─C Bond Forming Reactions
Kuhn verdazyls, discovered over 60 years ago, are shown as effective catalysts for the first time. Their tunable redox properties enable organocatalytic redox‐neutral C─H arylation and C─H trifluoromethylation reactions without light activation.
Shrouq Mujahed +4 more
wiley +2 more sources

