Results 71 to 80 of about 27,936 (236)

Phenazine Cations as Anticancer Theranostics

Journal of the American Chemical Society
The biological properties of two water-soluble organic cations based on polypyridyl structures commonly used as ligands for photoactive transition metal complexes designed to interact with biomolecules are investigated. A cytotoxicity screen employing a small panel of cell lines reveals that both cations show cytotoxicity toward cancer cells but show ...
Noakes, F.F., Smitten, K.L., Maple, L.E.C., Bernardino de la Serna, J., Robertson, C.C., Pritchard, D., Fairbanks, S.D., Weinstein, J.A., Smythe, C.G.W., Thomas, J.A.   +9 more
openaire   +4 more sources

Phenazin-5-ium bromide [PDF]

Acta Crystallographica Section E Structure Reports Online, 2012
In the title compound, C(12)H(9)N(2) (+)·Br(-), the protonated tricyclic ring system is slightly twisted, with a dihedral angle of 3.9 (1)° between the two outer benzene rings. In the crystal, N-H⋯Br and C-H⋯Br hydrogen bonds link two cations and two bromide anions into centrosymmetric assemblies, which are further packed into stacks along [010] via π ...
Gong-Xiao Zhang, Ping Li, Jian Dong, Hong-Yu Chen   +3 more
openaire   +3 more sources

Structural and Biochemical Characterization of the Diaminopimelate Epimerase DapF From Pseudomonas aeruginosa PA14

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The emergence of antibiotic resistance in bacteria is a major threat to global public health. To combat increasingly drug‐resistant bacteria like Pseudomonas aeruginosa, new targets for pharmaceuticals need to be explored. One such potential target for P.
Philipp Schneider, Claudia Hanko, Konrad Büssow, Stefan Schmelz, Wulf Blankenfeldt   +4 more
wiley   +1 more source

Phenazine 1- carboxylic acid (PCA) produced by Pseudomonas aeroginosa MUT.3: a study on its stability and antibacterial activity under various environmental conditions

یافته‌های نوین در علوم زیستی, 2020
Phenazine 1-corboxylic acid (PCA) is an antibiotic, which inhibits the growth of a vast number of micro-organisms. PCA has has been applied in fields such as pharmaceutical, agricultural, marine and chemical industries.
Ali Bahrami, Bita Jenabzadeh, Hamid Mosmeri, Mohammad Davoud Ghafari   +3 more
doaj  

Phenazine-1-Carboxamide Production in the Biocontrol Strain Pseudomonas chlororaphis PCL1391 Is Regulated by Multiple Factors Secreted into the Growth Medium

Molecular Plant-Microbe Interactions, 2001
Pseudomonas chlororaphis PCL1391 controls tomato foot and root rot caused by Fusarium oxysporum f. sp. radicislycopersici. The production of phenazine-1-carboxamide (PCN) is crucial for this biocontrol activity.
Thomas F. C. Chin-A-Woeng, Daan van den Broek, Gert de Voer, Koen M. G. M. van der Drift, Sietske Tuinman, Jane E. Thomas-Oates, Ben J. J. Lugtenberg, Guido V. Bloemberg   +7 more
doaj   +1 more source

Studies on Phenazines. XIX. Synthesis of Phenazine-carboxylic Acids.

Chemical and Pharmaceutical Bulletin, 1959
By oxidation with chromium trioxide in the presence of conc. sulfuric acid at about 5∼15°, 6-hydroxyphenazine-1- and 9-hydroxyphenazine-2-carboxylic acids were obtained from their respective methylphenazine derivatives.
openaire   +2 more sources

Development of Dibenzofuran Linkers and Phenazine-Based Redox-Responsive Foldamers

, 2023
Our group has demonstrated the feasibility of utilizing phenazine-1,6-dicarboxamides as redox-responsive molecular switches: changes in the oxidation state of the phenazine core forces the secondary amide arms to rotate between the doubly folded form ...
Son, Ruth
core   +1 more source

Unraveling the effect of topological structures of B/N‐doped conjugated macrocycles on spectral properties: A computational study

Smart Molecules, EarlyView.
Herein, we constructed a series of fully B‐doped, fully N‐doped and hybrid B/N‐doped conjugated macrocycles considering three key topological factors. At a fixed ring size, the spectra initially redshift then blueshift with varying B/N ratio, while ring size exhibits negligible impact on spectra.
Wen‐Yu Guo, Yi Zeng, Yu‐Meng Xu, Pang‐Kuan Chen, Xiao‐Yan Zheng   +4 more
wiley   +1 more source

Induction of Antibacterial Metabolites by Co-Cultivation of Two Red-Sea-Sponge-Associated Actinomycetes Micromonospora sp. UR56 and Actinokinespora sp. EG49

Marine Drugs, 2020
Liquid chromatography coupled with high resolution mass spectrometry (LC-HRESMS)-assisted metabolomic profiling of two sponge-associated actinomycetes, Micromonospora sp. UR56 and Actinokineospora sp.
Mohamed S. Hifnawy, Hossam M. Hassan, Rabab Mohammed, Mohamed M. Fouda, Ahmed M. Sayed, Ahmed A. Hamed, Sameh F. AbouZid, Mostafa E. Rateb, Hani A. Alhadrami, Usama Ramadan Abdelmohsen   +9 more
doaj   +1 more source

Pseudomonas aeruginosa Biofilm Response and Resistance to Cold Atmospheric Pressure Plasma Is Linked to the Redox-Active Molecule Phenazine. [PDF]

, 2015
Pseudomonas aeruginosa is an important opportunistic pathogen displaying high antibiotic resistance. Its resistance is in part due to its outstanding ability to form biofilms on a range of biotic and abiotic surfaces leading to difficult-to-treat, often ...
Ostrikov, Kostya, Mai-Prochnow, Anne, Kostya Ostrikov, Anthony B Murphy, Mark Bradbury, Murphy, Anthony B, Bradbury, Mark, Murphy, Anthony, Anne Mai-Prochnow   +8 more
core   +1 more source