Results 91 to 100 of about 6,115 (220)

The antitumor properties of metformin and phenformin reflect their ability to inhibit the actions of differentiated embryo chondrocyte 1

open access: yesCancer Management and Research, 2019
Chun-Lin Kuo,1 Shu-Man Hsieh Li,*,2 Shu-Yi Liang,*,2 Shu-Ting Liu,2 Li-Chun Huang,2 Wei-Ming Wang,3 Li-Chen Yen,2,4 Shih-Ming Huang21Department of Orthopaedic Surgery, Tri-Service General Hospital, National Defense Medical Center, Taiwan ...
Kuo CL   +7 more
doaj  

Glucose Deprivation Enhances the Antiproliferative Effects of Oral Hypoglycemic Biguanides in Different Molecular Subtypes of Breast Cancer: an in Vitro Study

open access: yesActa Pharmaceutica, 2018
Extensive in vitro studies have been conducted to evaluate the anticancer activity of oral hypoglycemic agents. Many of these studies experienced detrimental limitations, since they were conducted on cancer cells commonly grown in culture media ...
Bardaweel Sanaa K.   +3 more
doaj   +1 more source

Optimization of biguanide derivatives as selective antitumor agents blocking adaptive stress responses in the tumor microenvironment

open access: yesDrug Design, Development and Therapy, 2014
Kosuke Narise, Kensuke Okuda, Yukihiro Enomoto, Tasuku Hirayama, Hideko Nagasawa Laboratory of Pharmaceutical and Medicinal Chemistry, Gifu Pharmaceutical University, Daigaku-nishi, Gifu, Japan Abstract: Adaptive cellular responses resulting from ...
Narise K   +4 more
doaj  

Phenformin increases early hematopoietic progenitors in the Jak2V617F murine model

open access: yesInvestigational new drugs, 2022
Antônio Bruno Alves-Silva   +12 more
semanticscholar   +1 more source

TABLE 2 from Phase Ib Trial of Phenformin in Patients with V600-mutated Melanoma Receiving Dabrafenib and Trametinib

open access: gold, 2023
Paul B. Chapman   +11 more
openalex   +1 more source

FIGURE 1 from Phase Ib Trial of Phenformin in Patients with V600-mutated Melanoma Receiving Dabrafenib and Trametinib

open access: gold, 2023
Paul B. Chapman   +11 more
openalex   +1 more source

Repurposing phenformin for the targeting of glioma stem cells and the treatment of glioblastoma

open access: diamond, 2016
Wei Jiang   +8 more
openalex   +2 more sources

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