Results 41 to 50 of about 55,451 (338)

Phenobarbital Pharmacokinetics and Optimal Dosing of Phenobarbital

open access: yesPediatric Neurology Briefs, 2018
Researchers from the Baylor College of Medicine in Houston, TX, USA, conducted a retrospective population pharmacokinetic analysis of 355 patients ages less than 19 years of age in the inpatient setting who were initiated on intravenous or oral ...
Safiullah Shareef, Murtaza Nasir Ali
doaj   +1 more source

Antiepileptic Hypersensitivity Syndrome to Phenobarbital: A Case Report

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2019
Phenobarbital is still one of the most commonly used medical treatments for different types of seizures. It has numerous different side-effects. Antiepileptic hypersensitivity syndrome (AHS) is a rare and potentially life-threatening adverse reaction to ...
Zahra Nafei   +2 more
doaj   +1 more source

Side effects of phenobarbital and carbamazepine in childhood epilepsy: randomised controlled trial [PDF]

open access: yes, 2007
Objective: To compare the behavioural side effects associated with two commonly used antiepilepsy drugs--phenobarbital and carbamazepine--in children in Bangladesh. Design: Prospective randomised controlled single centre trial.
Banu, S.H.   +5 more
core  

International Veterinary Epilepsy Task Force Consensus Proposal: Outcome of therapeutic interventions in canine and feline epilepsy [PDF]

open access: yes, 2015
Common criteria for the diagnosis of drug resistance and the assessment of outcome are needed urgently as a prerequisite for standardized evaluation and reporting of individual therapeutic responses in canine epilepsy. Thus, we provide a proposal for the
A Neligan   +93 more
core   +7 more sources

Circulating tumor cells in metastatic breast cancer patients treated with immune checkpoint inhibitors – a biomarker analysis of the ALICE and ICON trials

open access: yesMolecular Oncology, EarlyView.
In this explorative biomarker analysis, we assessed serial sampling of circulating tumor cells (CTCs) with CellSearch in two randomized trials testing immune checkpoint inhibitors (ICIs) in metastatic breast cancer. Our data demonstrate a prognostic potential of CTCs, most apparent 4 weeks into ICI therapy.
Nikolai Kragøe Andresen   +13 more
wiley   +1 more source

Unraveling the metastasis‐preventing effect of miR‐200c in vitro and in vivo

open access: yesMolecular Oncology, EarlyView.
Advanced tumors and ineffective cancer treatments can lead to metastases in distant organs. The sole expression of microRNA 200c (miR‐200c) in breast cancer cells is shown to significantly reduce metastasis formation in xenograft mouse models. Various in vitro analyses revealed impeded migratory behavior, upon miR‐200c expression, as one prerequisite ...
Bianca Köhler   +12 more
wiley   +1 more source

Phenobarbital as alternate anticonvulsant for organophosphate‐induced benzodiazepine‐refractory status epilepticus and neuronal injury

open access: yesEpilepsia Open, 2020
Objective Organophosphates (OPs) such as diisopropylfluorophosphate (DFP) and soman are lethal chemical agents that can produce seizures, refractory status epilepticus (SE), and brain damage.
Doodipala Samba Reddy   +5 more
doaj   +1 more source

Ciradian dysrhythmias in the EEG of children with clonazepam treatment [PDF]

open access: yes, 1984
The effects of different anticonvulsants on the system of cir-cadian and ultradian rhythms in the EEG of children was investigated in ten 24*-h recordings of children with different forms of epilepsy.
Arbogast, B.   +4 more
core   +1 more source

Clinical significance of stratifying prostate cancer patients through specific circulating genes

open access: yesMolecular Oncology, EarlyView.
We tested a specific panel of genes representative of luminal, neuroendocrine and stem‐like cells in the blood of prostate cancer patients, showing predictive value from diagnosis to late stages of disease. This approach allows monitoring of treatment responses and outcomes at specific time points in trajectories.
Seta Derderian   +12 more
wiley   +1 more source

Pharmacological and non-pharmacological treatments for the Neonatal Abstinence Syndrome (NAS). [PDF]

open access: yes, 2019
Neonatal abstinence syndrome is defined by signs and symptoms of withdrawal that infants develop after intrauterine maternal drug exposure. All infants with documented in utero opioid exposure, or a high pre-test probability of exposure should have ...
Kraft, W. K.   +2 more
core   +1 more source

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