Results 41 to 50 of about 86,047 (385)

Ursodeoxycholic acid versus phenobarbital for cholestasis in the Neonatal Intensive Care Unit

open access: yesBMC Pediatrics, 2018
Background Although neonates and young infants with cholestasis are commonly treated with either phenobarbital or ursodeoxycholic acid (ursodiol), there is no evidence that phenobarbital is effective for this indication.
Tamorah Lewis   +2 more
doaj   +1 more source

Unsaturated fatty acid regulation of cytochrome P450 expression via a CAR-dependent pathway. [PDF]

open access: yes, 2008
The liver is responsible for key metabolic functions, including control of normal homoeostasis in response to diet and xenobiotic metabolism/detoxification.
Finn, Robert   +3 more
core   +4 more sources

The effectiveness of continuous venovenous hemodiafiltration in phenobarbital intoxication

open access: yesActa Medica International, 2018
Phenobarbital continues to be widely used in childhood epilepsy. Incorrect drug prescription can sometimes lead to intoxication, particularly in young children.
Yasemin Çoban   +4 more
doaj   +1 more source

Human targeted phenobarbital presents a poor substrate of gut microbiome deciphering new drug targets beyond pharmacokinetic curbs

open access: yesBMC Pharmacology and Toxicology, 2022
Background The gut microbiome, a new organ of the body, can potentially alter the pharmacokinetics of orally administered drugs through microbial enzymes.
Imran Mukhtar   +5 more
doaj   +1 more source

Stimulation of cholesterol 7α-hydroxylase by phenobarbital in two strains of rats

open access: yesJournal of Lipid Research, 1972
The effect of phenobarbital administration on the in vitro activity of cholesterol 7α-hydroxylase was investigated in two strains of rats. In rats of the Wistar strain the daily injection of phenobarbital (100 mg/kg per day ip for 5 days) produced a 33 ...
S. Shefer, S. Hauser, E.H. Mosbach
doaj   +1 more source

Behavioral and structural changes in the hippocampus of wistar epileptic rats are minimized by acupuncture associated or not with phenobarbital

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia, 2022
The aim of this study was to analyze the behavior and histopathological changes in the hippocampus of epileptic Wistar rats treated with acupuncture associated or not with phenobarbital.
T.C.C. Silva   +4 more
doaj   +1 more source

Measurement of Blood Phenobarbital Concentration in Newborns Admitted to The NICU of Imam Reza Hospital and Receiving The Drug Via Intravenous Mode [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology
Introduction: Newborns may be treated with phenobarbital for many reasons. Because in each region, depending on different races and genetic factors, different pharmacokinetic conditions govern the drug.
Hamidreza Goldouzi   +6 more
doaj   +1 more source

Seizure Disorders in Goats and Sheep. [PDF]

open access: yes, 2016
BackgroundGoats and sheep are more likely to be presented for examination for seizures than are cattle, possibly as a consequence of their relatively smaller body size.
Aleman, M, Chigerwe, M
core   +1 more source

The Evidence Behind the Treatment of Canine Idiopathic Epilepsy [PDF]

open access: yes, 2016
Oral phenobarbital and imepitoin in particular, followed by potassium bromide and levetiracetam are likely to be effective for the treatment of canine idiopathic epilepsy. There is strong evidence supporting the use of oral phenobarbital and imepitoin as
Brodbelt, D C   +2 more
core   +3 more sources

Phenobarbital Molecularly Imprinted Polymer Selectively Binds Phenobarbital.

open access: yesBiological and Pharmaceutical Bulletin, 1997
Molecularly imprinted polymer (MIP) was prepared against phenobarbital using methacrylic acid as the functional monomer and ethylene glycol dimethacrylate as the cross linking monomer. We analyzed the recognition properties of the phenobarbital MIP. In some organic solvents, imprinted polymer showed selective binding to phenobarbital.
Masahiro Niizeki   +6 more
openaire   +4 more sources

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