Interventions for treating hyperemesis gravidarum. [PDF]
BACKGROUND: Hyperemesis gravidarum is a severe form of nausea and vomiting in pregnancy affecting 0.3% to 1.0% of pregnancies, and is one of the most common indications for hospitalization during pregnancy.
Abas +96 more
core +2 more sources
A clinical trial of enteral Levetiracetam for acute seizures in pediatric cerebral malaria
Background Acute seizures are common in pediatric cerebral malaria (CM), but usual care with phenobarbital risks respiratory suppression. We undertook studies of enteral levetiracetam (eLVT) to evaluate pharmacokinetics (PK), safety and efficacy ...
Gretchen L. Birbeck +10 more
doaj +1 more source
In vitro Removal of Therapeutic Drugs with a Novel Adsorbent System [PDF]
Background/Aim: Substances in the middle molecular weight range have been shown to play a significant pathogenetic role in as diverse disorders as end-stage renal disease and multiple organ failure.
Bellomo, Rinaldo +10 more
core +1 more source
Antiepileptic Hypersensitivity Syndrome to Phenobarbital: A Case Report
Phenobarbital is still one of the most commonly used medical treatments for different types of seizures. It has numerous different side-effects. Antiepileptic hypersensitivity syndrome (AHS) is a rare and potentially life-threatening adverse reaction to ...
Zahra Nafei +2 more
doaj +1 more source
Antiepileptic drugs’ tolerability and safety – a systematic review and meta-analysis of adverse effects in dogs [PDF]
Various anti-epileptic drugs (AEDs) are used for the management of idiopathic epilepsy (IE) in dogs. Their safety profile is an important consideration for regulatory bodies, owners and prescribing clinicians.
A Stabile +105 more
core +3 more sources
Efficacy of phenobarbital is maintained after exposure to mild‐to‐moderate seizures in neonates
To study the relationship between the delay in treatment and the efficacy of phenobarbital in neonates, we re‐analyzed data from the NEOLEV2 study. Continuous video EEG (cEEG) from patients treated with phenobarbital was reviewed by neurophysiologists ...
Cynthia Sharpe +9 more
doaj +1 more source
Pharmacokinetic analysis of a phenobarbital overdose treated with urinary alkalinization alone
Phenobarbital is a long-acting barbiturate used to treat alcohol withdrawal and epilepsy. Acute overdoses present with varying levels of central nervous system depression and large overdoses can be life threatening.
Justin Seltzer +5 more
doaj +1 more source
Presumptive phenobarbital‐induced systemic lupus erythematosus in a domestic dog
Case Description We describe a case of presumptive acquired systemic lupus erythematosus secondary to phenobarbital administration in a dog, which resolved with withdrawal of the drug.
Erin Phillips +5 more
doaj +1 more source
ABSTRACT Secondary hyperparathyroidism (SHPT) is a common complication in patients receiving maintenance dialysis, driven by calcium and phosphate metabolism disturbances. Calcimimetics are central to the management of SHPT by enhancing calcium‐sensing receptor sensitivity and reducing parathyroid hormone secretion.
Fumihiko Koiwa +3 more
wiley +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source

