Results 61 to 70 of about 36,304 (274)

A 3D Biofabricated Disease Model Mimicking the Brain Extracellular Matrix Suitable to Characterize Intrinsic Neuronal Network Alterations in the Presence of a Breast Tumor Disseminated to the Brain

Advanced Functional Materials, EarlyView.
A 3D disease model is developed using customized hyaluronic‐acid‐based hydrogels supplemented with extracellular matrix (ECM) proteins resembling brain ECM properties. Neurons, astrocytes, and tumor cells are used to mimic the native brain surrounding.
Esra Türker, Mateo S. Andrade Mier, Jessica Faber, Mike Friedrich, Zan Lamberger, Jeannette Weigelt, Christian Stigloher, Nicoletta Murenu, Natascha Schaefer, Jörg Tessmar, Gregor Lang, Silvia Budday, Katrin G. Heinze, Antje Appelt‐Menzel, Pamela L. Strissel, Reiner Strick, Carmen Villmann   +16 more
wiley   +1 more source

A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis

Advanced Functional Materials, EarlyView.
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria, Adriana Blazeski, Eunkyung Clare Ko, Tran Thai, Shania Dantes, David A. Barbie, Sarah E. Shelton, Roger D. Kamm   +7 more
wiley   +1 more source

MAGTWIST: A Magnetically‐Driven Rotary Actuator Using a Traveling‐Wave With Integrated Stiffness Tunability

Advanced Functional Materials, EarlyView.
MAGTWIST: A compact magnetic rotary actuator, enabling smooth, stepless rotation, and on‐demand locking. Inspired by peristalsis, a soft polymer belt generates a traveling‐wave, enabling 270° rotation when heated. Cooling stiffens the belt, locking it in position and enabling it to withstand high loads.
Simon Frieler, Jean‐Paul P.M. de Vries, Sarthak Misra, Venkatasubramanian Kalpathy Venkiteswaran   +3 more
wiley   +1 more source

Clinical presentation and laboratory determination of Phenobarbital overdose

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 1999
Objective: Barbiturates as hypnotic drugs are widely used in medicine. They act as sedative or analgesic and are used to control seizure disorders. References show that the number cases of poisoning by this drug is very high.
M Abdollahi, H Binesh, S Nikfar, N Jallali, AA Moghadam Nia   +4 more
doaj  

Effectiveness of Continuous Veno-Venous Hemofiltration and Intermittent Hemodialysis in the Treatment of Severe Acute Phenobarbital Poisoning [PDF]

Asia Pacific Journal of Medical Toxicology, 2013
Background: Phenobarbital poisoning is common in Vietnam. The aim of this study was to compare the effectiveness of continuous veno-venous hemofiltration (CVVH) and hemodialysis (HD) on clinical outcomes in the treatment of severe acute phenobarbital ...
Le Quang Thuan, Ngo Duc Ngoc, Pham Due
doaj  

Suspected phenobarbital-induced fever in a cat

Journal of Feline Medicine and Surgery Open Reports, 2019
Case summary A 3-year-old spayed female domestic shorthair cat developed a fever 1 week after starting the anticonvulsant phenobarbital. A diagnostic work-up for seizures and subsequent onset of fever of unknown origin, consisting of MRI of the brain ...
Dylan M Djani, William E Draper
doaj   +1 more source

Prolonged jaundice in newborns is a common condition that affects many infants: A case study [PDF]

Journal of Nursing Reports in Clinical Practice
This study aimed to evaluate prolonged jaundice in a newborn. A 30-day-old infant (male) with a bilirubin level of 8 mg/dL at birth, which increased to 11.0 mg/dL on day 10, was treated with phenobarbital. By day 29, the bilirubin level had risen to 11.3
Roohallah Yousefi, Saleh Shojaie, Masoomeh Yousefi   +2 more
doaj   +1 more source

Serum NMR metabolomics uncovers multiple metabolic changes in phenobarbital-treated dogs [PDF]

, 2021
Claudia Ottka, Corinna Weber, Elisabeth Müller, Hannes Lohi   +3 more
openalex   +1 more source

Unraveling the Heterogeneity of Cargo Distribution in the Exogenous Association of Proteins With Extracellular Vesicles

Advanced Healthcare Materials, EarlyView.
We characterized the distribution of cargo proteins associated with extracellular vesicles using various exogenous loading methods. In all cases, single‐particle analysis revealed that the distribution of protein content per EV is heterogeneous, following an exponential decay function.
Karl Normak, Marcell Papp, Carolina Paganini, Andrea Zendrini, Paolo Bergese, Dorothea Pinotsi, Paolo Arosio   +6 more
wiley   +1 more source

A Comparison of Parenteral Phenobarbital vs. Parenteral Phenytoin as Second-Line Management for Pediatric Convulsive Status Epilepticus in a Resource-Limited Setting

Frontiers in Neurology, 2019
Introduction: Pediatric convulsive status epilepticus (CSE) which is refractory to first-line benzodiazepines is a significant clinical challenge, especially within resource-limited countries.
Richard J. Burman, Richard J. Burman, Sally Ackermann, Alexander Shapson-Coe, Alvin Ndondo, Alvin Ndondo, Heloise Buys, Jo M. Wilmshurst, Jo M. Wilmshurst   +8 more
doaj   +1 more source