Stimulation of cholesterol 7α-hydroxylase by phenobarbital in two strains of rats
Journal of Lipid Research, 1972 The effect of phenobarbital administration on the in vitro activity of cholesterol 7α-hydroxylase was investigated in two strains of rats. In rats of the Wistar strain the daily injection of phenobarbital (100 mg/kg per day ip for 5 days) produced a 33 ...
S. Shefer, S. Hauser, E.H. Mosbach
doaj
Toxic epidermal necrolysis caused by phenobarbital: a case report and literature review
Frontiers in PharmacologyBackgroundToxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are rare, life-threatening immunologic reactions. Previous relevant literature has provided limited information regarding this disease’s genetic susceptibility and management ...
Jie Cheng +7 more
doaj +1 more source
Acta Cirúrgica Brasileira, 2008 PURPOSE: To evaluate in vitro and in vivo neuromuscular blockade produced by rocuronium in rats treated with Phenobarbital and to determine cytochrome P450 and cytochrome b5 concentrations in hepatic microsomes.
Angélica de Fátima de Assunção Braga +6 more
doaj +1 more source
Differential effects of clinically used derivatives and metabolites of artemisinin in the activation of constitutive androstane receptor isoforms [PDF]
, 2012 BACKGROUND AND PURPOSE Widespread resistance to antimalarial drugs requires combination therapies with increasing risk of pharmacokinetic drugdrug interactions.
Alexander +51 more
core +1 more source
A Patch Test Confirmed Phenobarbital-Induced Fixed Drug Eruption in a Child
Iranian Journal of Allergy, Asthma and Immunology, 2014 A-10-year-old girl was referred to our department for multiple hyperpigmented plaques. One week previously, she had been given one suppository of acetylsalicylic acid – phenobarbital for fever.
Zohra Chadly +5 more
doaj
Suspected phenobarbital-induced fever in a cat
Journal of Feline Medicine and Surgery Open Reports, 2019 Case summary A 3-year-old spayed female domestic shorthair cat developed a fever 1 week after starting the anticonvulsant phenobarbital. A diagnostic work-up for seizures and subsequent onset of fever of unknown origin, consisting of MRI of the brain ...
Dylan M Djani, William E Draper
doaj +1 more source
5-hydroxymethylcytosine profiling as an indicator of cellular state [PDF]
, 2013 A Laird is supported by the Medical Research Council Scottish Clinical Pharmacology and Pathology Programme, The Royal College of Surgeons of Edinburgh Robertson’s Trust and The Melville Trust for the Care and Cure of Cancer.
Harrison, David J. +3 more
core +1 more source
Effectiveness of Continuous Veno-Venous Hemofiltration and Intermittent Hemodialysis in the Treatment of Severe Acute Phenobarbital Poisoning [PDF]
Asia Pacific Journal of Medical Toxicology, 2013 Background: Phenobarbital poisoning is common in Vietnam. The aim of this study was to compare the effectiveness of continuous veno-venous hemofiltration (CVVH) and hemodialysis (HD) on clinical outcomes in the treatment of severe acute phenobarbital ...
Le Quang Thuan, Ngo Duc Ngoc, Pham Due
doaj
Newer drugs for focal epilepsy in adults [PDF]
, 2012 A 28 year old woman sees her general practitioner after experiencing what sounds like a convulsion without any apparent provoking factor. Over the past month she has also had “blank spells” during which her husband noticed her to be unresponsive.
Brodie, M., Kwan, P.
core +1 more source
Clinical presentation and laboratory determination of Phenobarbital overdose
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 1999 Objective: Barbiturates as hypnotic drugs are widely used in medicine. They act as sedative or analgesic and are used to control seizure disorders. References show that the number cases of poisoning by this drug is very high.
M Abdollahi +4 more
doaj