Results 81 to 90 of about 55,451 (338)

Effect of S‐1 on blood levels of phenobarbital and phenytoin: A case report

Clinical Case Reports, 2021
Drug‐drug interaction of fluorinated pyrimidine anticancer agents with phenytoin is well known, but interaction with phenobarbital is limited. We describe a case showing increases in plasma phenobarbital as well as phenytoin concentrations during ...
Ken Shiraiwa, Hiroyuki Ono, Ryota Tanaka, Atsuro Fujinaga, Takahiro Hiratsuka, Ryosuke Tatsuta, Masafumi Inomata, Hiroki Itoh   +7 more
doaj   +1 more source

Interpenetrating Polymer Network Hydrogels with Tunable Viscoelasticity and Proteolytic Cleavability to Direct Stem Cells In Vitro

Advanced Healthcare Materials, EarlyView.
A cell‐instructive hydrogel platform is introduced of interpenetrating polymer networks (IPNs) containing sulfated glycosaminoglycan (sGAG) and polyethylene glycol cross‐linked through chemical and physical interactions, respectively. The materials allow for the precise systematic modulation of stiffness, viscoelasticity, and proteolytic cleavability ...
Prannoy Seth, Jens Friedrichs, Yanuar Dwi Putra Limasale, Nicole Fertala, Uwe Freudenberg, Yixin Zhang, Ayala Lampel, Carsten Werner   +7 more
wiley   +1 more source

Stimulation of cholesterol 7α-hydroxylase by phenobarbital in two strains of rats

Journal of Lipid Research, 1972
The effect of phenobarbital administration on the in vitro activity of cholesterol 7α-hydroxylase was investigated in two strains of rats. In rats of the Wistar strain the daily injection of phenobarbital (100 mg/kg per day ip for 5 days) produced a 33 ...
S. Shefer, S. Hauser, E.H. Mosbach
doaj  

Phenobarbital influence on neuromuscular block produced by rocuronium in rats Influência do fenobarbital no bloqueio neuromuscular produzido pelo rocurônio em ratos

Acta Cirúrgica Brasileira, 2008
PURPOSE: To evaluate in vitro and in vivo neuromuscular blockade produced by rocuronium in rats treated with Phenobarbital and to determine cytochrome P450 and cytochrome b5 concentrations in hepatic microsomes.
Angélica de Fátima de Assunção Braga, Caroline Coutinho de Barcelos, Franklin Sarmento da Silva Braga, Samanta Cristina Antoniassi Fernandes, Yoko Oshima Franco, Mario Mantovani, Léa Rodrigues Simioni   +6 more
doaj   +1 more source

Withdrawal of parenteral phenobarbitone - Implications for resource-poor countries [PDF]

, 2005
Parenteral phenobarbitone is an integral part of the management of status epilepticus, especially in the context of resource-poor countries. It is highly effective at controlling seizures.
Newton, CRJC, van Toorn, R, Wilmshurst, JM   +2 more
core  

Leveraging Organ‐on‐Chip Models to Investigate Host–Microbiota Dynamics and Targeted Therapies for Inflammatory Bowel Disease

Advanced Healthcare Materials, EarlyView.
The challenges of studying inflammatory bowel disease (IBD), highlighting limitations of traditional 2D cell cultures and animal models are discussed here. It introduces human intestine organ‐on‐chip (OoC) models as a promising alternative, capable of more accurately mimicking the intestinal microenvironment.
Tim Kaden, Raquel Alonso‐Román, Johannes Stallhofer, Mark S. Gresnigt, Bernhard Hube, Alexander S. Mosig   +5 more
wiley   +1 more source

A Patch Test Confirmed Phenobarbital-Induced Fixed Drug Eruption in a Child

Iranian Journal of Allergy, Asthma and Immunology, 2014
A-10-year-old girl was referred to our department for multiple hyperpigmented plaques. One  week  previously,  she  had  been  given  one  suppository  of  acetylsalicylic acid  – phenobarbital for fever.
Zohra Chadly, Karim Aouam, Amel Chaabane, Hichem Belhadjali, Naceur Abderrazzak Boughattas, Jamel Eddine Zili   +5 more
doaj  

Urine‐Stable Aptamer‐Conjugated Gold Nanorods for the Early Detection of High‐Grade Bladder Cancer Residual Disease

Advanced Healthcare Materials, EarlyView.
Aptamer (A) conjugated gold nanorods (B) for the recognition of bladder cancer cells expressing the integrin α5β1 (C) and the visualization of the targeted GNRs@Chit‐Apt‐Itg by photoacoustic imaging at the surface of the orthotopic bladder cancer in the preclinical model (D).
Chiara Venegoni, Silvia Tortorella, Alessandra Caliendo, Irene Locatelli, Alessia Di Coste, Erica Locatelli, Filippo Capancioni, Emanuela Bua, Simona Camorani, Andrea Salonia, Francesco Montorsi, Jithin Jose, Marco Moschini, Laura Cerchia, Mauro Comes Franchini, Massimo Alfano   +15 more
wiley   +1 more source

A Comparison of Parenteral Phenobarbital vs. Parenteral Phenytoin as Second-Line Management for Pediatric Convulsive Status Epilepticus in a Resource-Limited Setting

Frontiers in Neurology, 2019
Introduction: Pediatric convulsive status epilepticus (CSE) which is refractory to first-line benzodiazepines is a significant clinical challenge, especially within resource-limited countries.
Richard J. Burman, Richard J. Burman, Sally Ackermann, Alexander Shapson-Coe, Alvin Ndondo, Alvin Ndondo, Heloise Buys, Jo M. Wilmshurst, Jo M. Wilmshurst   +8 more
doaj   +1 more source

Quality-of-life aspects in idiopathic epilepsy in dogs [PDF]

, 2016
Quality of life (QoL) plays a significant role in the treatment of dogs with idiopathic epilepsy (IE), yet is so far understudied. This study describes the outcome evaluation of an online questionnaire based on the carer's perception focusing on 62 QoL ...
CHANG, CUSHNER-WEINSTEIN, FERRO, FREDSØ, HENN, JOKINEN, KOOLHAAS, KWAN, LEE, LIU, LORD, LV, MOHANRAJ, MONTEIRO, MUÑANA, NIESSEN, PACKER, PACKER, PACKER, SAITO, SHIHAB, WESSMANN, WILLIAMS   +22 more
core   +2 more sources