Results 91 to 100 of about 1,759 (167)

To know or not to know? Opinions of patients with Parkinson’s Disease on disclosing risk of phenoconversion in RBD

, 2023
Aneta Marcinkowska, Andrzej Bogucki, Aleksandra Kroemeke, Agata Gajos   +3 more
openalex   +2 more sources

Insular monoaminergic deficits in prodromal α‐synucleinopathies

Annals of Clinical and Translational Neurology
Methods This study assessed data from two cohorts of patients with alpha‐synucleinopathies (University of Brescia and University of Rome Tor‐Vergata cohorts).
Andrea Pilotto, Alice Galli, Cinzia Zatti, Fabio Placidi, Francesca Izzi, Enrico Premi, Silvia P. Caminiti, Luca Presotto, Andrea Rizzardi, Marcello Catania, Alessandro Lupini, Leandro Purin, Maria P. Pasolini, Nicola B. Mercuri, Agostino Chiaravalotti, Mariana Fernandes, Carmen Calvello, Silvia Lucchini, Francesco Bertagna, Barbara Paghera, Daniela Perani, Daniela Berg, Alessandro Padovani, Claudio Liguori   +23 more
doaj   +1 more source

Blunted tachycardia and cardiac sympathetic denervation in isolated rapid eye movement sleep behavior disorder

BMC Neurology
Background Isolated rapid eye movement sleep behavior disorder (iRBD) serves as a prodromal phase of Parkinson’s disease (PD) and dementia with Lewy bodies (DLB).
Shota Saeda, Yukiyoshi Sumi, Koichi Fujiwara, Hiroshi Kadotani   +3 more
doaj   +1 more source

The utility of neuro-QOL in idiopathic REM sleep behavior disorder

Sleep Science and Practice
Introduction Idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD) can affect quality of life (QOL) for both patient and bed partner; has been less well-studied.
Daniel A. Barone, Harini Sarva, Natalie Hellmers, Fei Wang, Zhenxing Xu, Ana C. Krieger, Claire Henchcliffe   +6 more
doaj   +1 more source

Pharmacogenetic guided drug therapy – how to deal with phenoconversion in polypharmacy

Expert Opinion on Drug Metabolism & Toxicology
The prevalence of polypharmacy and the increasing availability of pharmacogenetic information in clinical practice have raised the prospect of data-driven clinical decision-making when addressing the issues of drug-drug interactions and genetic polymorphisms in metabolizing enzymes.
Julia Carolin Stingl, Roberto Viviani
openaire   +2 more sources

Pharmacogenetic CYP2D6 variability, phenoconversion and treatment outcomes: A Danish population-based cohort study in 6,798 individuals initiating atomoxetine treatment [PDF]

, 2022
Kazi Ishtiak‐Ahmed, C. Lunenburg, J. Thirstrup, Loa Clausen, P. Thomsen, Christiane Gasse   +5 more
openalex   +1 more source

Editorial: Prodromal stage of neurodegenerative proteinopathies: from bench to bedside

Frontiers in Neuroscience, 2023
Bin Xu, Bin Xu, Seyed-Mohammad Fereshtehnejad, Seyed-Mohammad Fereshtehnejad, Yashar Zeighami, Yashar Zeighami   +5 more
doaj   +1 more source

Imaging advances to detect non-motor prodromal markers of Parkinson’s disease and explore therapeutic translation opportunities

npj Parkinson's Disease
Parkinson’s disease (PD) is a progressive neurological disorder marked by late-emerging motor symptoms, but early non-motor signs like hyposmia and REM sleep behavior disorder may precede diagnosis by years.
Mathangi Palanivel, Krishna Kanta Ghosh, Madhav Mallam, Raghavan Bhuvanakantham, Parasuraman Padmanabhan, Kah-Leong Lim, Balázs Gulyás   +6 more
doaj   +1 more source

0715 Machine Learning Model to Predict Isolated REM Sleep Behavior Disorder Phenoconversion Time and Subtype using EEG [PDF]

, 2023
El Jeong, Yong Woo Shin, Jung‐Ick Byun, Jun‐Sang Sunwoo, Han‐Joon Kim, Sun Jung Han, Ki‐Young Jung   +6 more
openalex   +1 more source

Alpha-synuclein-induced stress sensitivity renders the Parkinson’s disease brain susceptible to neurodegeneration

Acta Neuropathologica Communications
A link between chronic stress and Parkinson’s disease (PD) pathogenesis is emerging. Ample evidence demonstrates that the presynaptic neuronal protein alpha-synuclein (asyn) is closely tied to PD pathogenesis.
Modestos Nakos Bimpos, Katerina Karali, Christine Antoniou, Dionysios Palermos, Maria Fouka, Anastasios Delis, Iason Tzieras, George Panagiotis Chrousos, Yassemi Koutmani, Leonidas Stefanis, Alexia Polissidis   +10 more
doaj   +1 more source