Results 171 to 180 of about 3,015 (189)

Prevalence Estimates of Cytochrome P450 Phenoconversion in Youth Receiving Pharmacotherapy for Mental Health Conditions. [PDF]

open access: yesClin Pharmacol Ther
Gerlach S   +7 more
europepmc   +1 more source

The Many Faces of REM Sleep Behavior Disorder. Providing Evidence for a New Lexicon. [PDF]

open access: yesEur J Neurol
Arnaldi D   +18 more
europepmc   +1 more source

Clinical characteristics and phenoconversion in isolated REM sleep behavior disorder: a prospective single-center study in Korea, compared with Montreal cohort. [PDF]

open access: yesJ Clin Sleep Med
Byun JI   +13 more
europepmc   +1 more source

Validation of RBDtector: An Open-Source Automated Software for Scoring REM Sleep Without Atonia. [PDF]

open access: yesJ Sleep Res
Joza S   +7 more
europepmc   +1 more source

Phase II pilot randomized trial of zonisamide for disease modification in prodromal Lewy body disease. [PDF]

open access: yesNPJ Parkinsons Dis
Hiraga K   +20 more
europepmc   +1 more source

CYP2D6 pharmacogenetics and phenoconversion in personalized medicine

Expert Opinion on Drug Metabolism & Toxicology, 2022
CYP2D6 contributes to the metabolism of approximately 20-25% of drugs. However, CYP2D6 is highly polymorphic and different alleles can lead to impacts ranging from null to increase in activity. Moreover, there are commonly used drugs that potently inhibit the CYP2D6, thus causing 'phenoconversion' which can convert the genotypic normal metabolizer into
Noor A, Nahid, Julie A, Johnson
openaire   +2 more sources

Phenocopy and Phenoconversion: Do they Complicate Association Studies?

Pharmacogenomics, 2012
Current pharmacogenetic focus on genotype A number of clinically relevant drug metabo­ lizing enzymes (DMEs) are expressed poly­ morphically in the population, giving rise to at least three distinct genotypes; extensive metabolizers (EMs), poor metabolizers (PMs) and intermediate metabolizers.
Rashmi R, Shah, Robert L, Smith
openaire   +2 more sources

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