DNA Replication Errors Drive Genome‐Wide Small Inverted Triplication Dynamics
Advanced Science, EarlyView.This study provides insight into the dynamic equilibrium mechanism of a novel structural variant, small inverted triplication (SIT), which is generated by misalignment of the 3’ flap generated under DNA replication stress with palindromic sequence. Alternatively, the end sequence may fold back on itself to form an inverted fragment.
Yi Lei +12 more
wiley +1 more source
Mitigation of acrylamide in cookies and crispbread using calcium salts and phenolic acids in combination with asparaginase as well as rosemary extract. [PDF]
Food Chem XMusa S, Oellig C, Scherf KA.
europepmc +1 more source
Advanced Science, EarlyView.Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng +11 more
wiley +1 more source
Phenolic Acids Commonly Found in Natural Products Modulate Protein Aggregation in <i>Caenorhabditis elegans</i> Neurodegeneration Models. [PDF]
ACS OmegaValle-Jiménez X +2 more
europepmc +1 more source
Extraction, isolation and utilization of bioactive compounds from fruit juice industry waste [PDF]
, 2017 Chockchaisawasdee, Suwimol +1 more
core
Studying Macromolecular Composition in Cell–Cell Interfaces Using 3D Membrane Reconstitution Systems
Advanced Science, EarlyView.A comprehensive understanding of the interactions between proteins, lipids and glycocalyx components at the immune synapse is still lacking. Here, an artificial and a semi‐artificial model contact system were established to reconstitute the cell‐cell contact in 3D. The model systems enable the examination of macromolecule enrichment or depletion at the
Franziska Ragaller +9 more
wiley +1 more source
Flavonoid Glycosides and Phenolic Acids from Inula Oculus-Christi Modulate Membrane Organization and Provide Antioxidant Protection. [PDF]
MoleculesVeleva R +10 more
europepmc +1 more source
Advanced Science, EarlyView.This study systematically compares the degradation efficiency of CIP in a H2O2‐alone system and a novel Bi12FeO20‐H2O2 photo‐Fenton system. It reveals for the first time the presence of a quinone‐imine intermediate in the H2O2‐alone system, which exhibits toxicity comparable to CIP.
Wenting Qiu +9 more
wiley +1 more source
Optimal Extraction of Antioxidants, Flavonoids, and Phenolic Acids from the Leaves of <i>Apocynum venetum</i> L. by Response Surface Methodology with Integrated Chemical Profiles and Bioactivity Evaluation. [PDF]
MoleculesQin R, Song J, Wang Q, Guan Y, Lv C.
europepmc +1 more source
Advanced Science, EarlyView.A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park +11 more
wiley +1 more source