Results 51 to 60 of about 159,474 (293)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Exploring the capacity of endophytic fungi isolated from medicinal plants for fermentation and phenolics biotransformation of rose oil distillation wastewater

Biotechnology & Biotechnological Equipment, 2019
A total of 139 endophytic fungal isolates derived from 20 medicinal and aromatic plants were tested for their capacity to ferment rose oil distillation wastewater (RODW).
Mila Rusanova, Krasimir Rusanov, Veronika Butterweck, Ivan Atanassov   +3 more
doaj   +1 more source

A Comparison of the Chemical Composition, In Vitro Bioaccessibility and Antioxidant Activity of Phenolic Compounds from Rice Bran and Its Dietary Fibres

Molecules, 2018
The composition, in vitro bioaccessibility and antioxidant activities of the phenolic compounds in defatted rice bran (DRB) and its soluble and insoluble dietary fibres were systematically evaluated in this study.
Guanghe Zhao, Ruifen Zhang, Lihong Dong, Fei Huang, Lei Liu, Yuanyuan Deng, Yongxuan Ma, Yan Zhang, Zhencheng Wei, Juan Xiao, Mingwei Zhang   +10 more
doaj   +1 more source

Species-specific effects of elevated ozone on wetland plants and decomposition processes [PDF]

, 2010
Seven species from two contrasting wetlands, an upland bog and a lowland rich fen in North Wales, UK, were exposed to elevated ozone (150 ppb for 5 days and 20 ppb for 2 days per week) or low ozone (20 ppb) for four weeks in solardomes.
Freeman, Chris, Mills, Gina, Williamson, Jennifer   +2 more
core   +1 more source

Tree defence and bark beetles in a drying world: carbon partitioning, functioning and modelling. [PDF]

, 2020
Drought has promoted large-scale, insect-induced tree mortality in recent years, with severe consequences for ecosystem function, atmospheric processes, sustainable resources and global biogeochemical cycles.
Almuth Hammerbacher, Amy M. Trowbridge, Arjan J. H. Meddens, Chonggang Xu, Devin W. Goodsman, Dineshkumar Kandasamy, Henrik Hartmann, Henry D. Adams, Jianbei Huang, Jonathan Gershenzon, Kenneth F. Raffa, Li W, Markus Kautz, Raffa KF, Raffa KF, Rupert Seidl   +15 more
core   +1 more source

PHENOL COEFFICIENTS

American Journal of Public Health, 1921
The author states that a phenol coefficient indicates relative germicidal efficiency under laboratory conditions only, and has no practical value. Users of disinfectants ordinarily “follow directions,” and employ the dilutions recommended by the manufacturers.
openaire   +3 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Effects of selenium biofortification on crop nutritional quality [PDF]

, 2015
Selenium (Se) at very low doses has crucial functions in humans and animals. Since plants represent the main dietary source of this element, Se-containing crops may be used as a means to deliver Se to consumers (biofortification). Several strategies have
Dall'Acqua, Stefano, Elizabeth A. H., Pilon Smits, Malagoli, Mario, Schiavon, Michela   +3 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Multiple roles for UV RESISTANCE LOCUS8 in regulating gene expression and metabolite accumulation in arabidopsis under solar ultraviolet radiation [PDF]

, 2013
Photomorphogenic responses triggered by low fluence rates of ultraviolet B radiation (UV-B; 280–315 nm) are mediated by the UV-B photoreceptor UV RESISTANCE LOCUS8 (UVR8).
Aphalo, P.J., Brosche, M., Jenkins, G.I., Lindfors, A.V., Morales, L.O., Sipari, N., Strid, A., Tegelberg, R., Vainonen, J., Wargent, J.J.   +9 more
core   +1 more source