Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Hydrogen bonding in the recovery of phenols and methyl-t-butyl ether : molecular modeling and calorimetry [PDF]
The purification of waste water is very important, for clean potable water is a common good and a necessity. Surface water purification is nowadays carried out on a massive industrial scale, and clean water is at our disposal virtually everywhere and ...
Cuypers, R.
core
Kinetic modelling of phenols consumption during polyethylene thermal oxidation [PDF]
Irganox 1010 stabilized PE was monitored by carbonyl build-up and DSC under oxygen. A scheme for PE stabilization by phenols was implemented and its kinetic parameters were calculated from experimental results.
RICHAUD, Emmanuel
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Dielectric Absorption at 3 cm. in Some Higher Alkyl Phenols [PDF]
Dielectric measurements have been carried out on para-octyl, -nonyl and -dodecyl phenols in solution in benzene at 3.22 cm. and at a radio frequency of 1 mc/sec. From the measurements at 3.22 cm.
Hiremath, G C, Rao, K Suryanarayana
core
The aim of this work was to evaluate the effect of Salicylic acid, 2,4-D and 2-iP on the production of total phenolic and flavonoids as well in the levels of fukugetin and 7-epiclusianone in callus of Garcinia brasiliensis zygotic embryos.
Maria Gessi Teixeira +5 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Phytochemical, Antibacterial and Antioxidant Activity Evaluation of Rhodiola crenulata
The chemical components, as well as the antibacterial and antioxidant activities of the essential oil (EO) and crude extracts prepared from Rhodiola crenulata were investigated. The essential oil was separated by hydrodistillation, and gas chromatography-
Lingyun Zhong +5 more
doaj +1 more source
Subcritical water extraction of polyphenols from endemic Algerian plants with medicinal properties [PDF]
Ephedra alata, Ononis angustissima, and Genista saharae are endemic Algerian plants with pharmacological potential, used for centuries in traditional medicine. Herein the efficiency of subcritical water extraction (SWE) of phenols and flavonoids
Benmerzoug Abdelmoumen +4 more
doaj +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source

