Results 51 to 60 of about 125,915 (317)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Phytochemical, Antibacterial and Antioxidant Activity Evaluation of Rhodiola crenulata

Molecules, 2020
The chemical components, as well as the antibacterial and antioxidant activities of the essential oil (EO) and crude extracts prepared from Rhodiola crenulata were investigated. The essential oil was separated by hydrodistillation, and gas chromatography-
Lingyun Zhong, Lianxin Peng, Jia Fu, Liang Zou, Gang Zhao, Jianglin Zhao   +5 more
doaj   +1 more source

Subcritical water extraction of polyphenols from endemic Algerian plants with medicinal properties [PDF]

Acta Periodica Technologica, 2020
Ephedra alata, Ononis angustissima, and Genista saharae are endemic Algerian plants with pharmacological potential, used for centuries in traditional medicine. Herein the efficiency of subcritical water extraction (SWE) of phenols and flavonoids
Benmerzoug Abdelmoumen, Švarc-Gajić Jaroslava, Nastić Nataša, Guettaf Sofiane, Harzallah Daoud   +4 more
doaj   +1 more source

Aerobic Oxybromination of Phenols Catalyzed by Sodium Nitrite under Mild Conditions

, 2011
Aerobic Oxybromination of Phenols Catalyzed by Sodium Nitrite under Mild ConditionsAn efficient catalytic system for oxybromination of phenols under mild conditions has been developed, which utilizes sodium nitrite as the catalyst, dioxygen or air as the
张国富, Xu, Li, Wen, Xin, Liang, Xinmiao, Ding, Chengrong, Wang, Yong, Zhang, Guofu   +6 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Winemaking Byproducts as Source of Antioxidant Components: Consumers’ Acceptance and Expectations of Phenol-Enriched Plant-Based Food

Antioxidants, 2020
One of the food industry’s priorities is to recover byproducts and move towards more sustainable systems. Among wine-chain byproducts, unripe grapes represent a promising source of antioxidants. However, the development of new foods enriched using phenol-
Cristina Proserpio, Giovanna Fia, Ginevra Bucalossi, Bruno Zanoni, Sara Spinelli, Caterina Dinnella, Erminio Monteleone, Ella Pagliarini   +7 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Teores de fenóis totais e taninos nas cascas de angico-vermelho (Anadenanthera peregrina)

Floresta e Ambiente
Este trabalho teve como objetivo quantificar fenóis totais e taninos nas cascas de angico-vermelho (Anadenanthera peregrina) em diferentes classes de diâmetro, além de comparar duas metodologias de quantificação de fenóis.
Caroline Junqueira Sartori, Ana Hortência Fonsêca Castro, Fabio Akira Mori   +2 more
doaj   +1 more source

Nanocomposites Photocatalysis Application for the Purification of Phenols and Real Olive Mill Wastewater through a Sequential Process

Applied Sciences, 2020
In this study, a synthetic phenol solution of water and raw olive mill wastewater (OMW) were considered to achieve purification of the aqueous streams from pollutants.
Srikanth Vuppala, Marco Stoller
doaj   +1 more source

Various techniques for phenolic removal from olive mill wastewater

Croatian Journal of Food Science and Technology, 2021
As the world's population increases, so does the amount of wastewater generated during agricultural activities. Inadequate wastewater management can be the cause of sea and river pollution.
Melita Lončarić, Mirna Habuda-Stanić, Maja Molnar   +2 more
doaj   +1 more source