Molecular Oncology, EarlyView.Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma +9 more
wiley +1 more source
Endogenous levels of reducing sugars, free amino acids and phenols during various stages of in vitro culture of cotton (Gossypium Spp.) [PDF]
, 2010 Somatic embryogenesis is widely preferred as the regeneration route for in vitro studies in cotton. However, the regeneration efficiency through this approach is low; a problem that is believed to be as a result of the biochemical properties of the ...
Obembe, Olawole O.
core
Re-designing the substrate binding pocket of laccase for enhanced oxidation of sinapic acid [PDF]
, 2016 Iterative saturation mutagenesis was performed over six residues delimiting the substrate binding pocket of a high-redox potential chimeric laccase with the aim of enhancing its activity over sinapic acid, a lignin-related phenol of industrial interest ...
Camarero, Susana +9 more
core +1 more source
Comparison of antioxidant and antimicrobial activities of extracts obtained from Salvia glutinosa L. and Salvia officinalis L. [PDF]
Hemijska Industrija, 2011 Antioxidant and antimicrobial activities as well as total phenols and flavonoids contents of Salvia glutinosa L. (glutinous sage) and Salvia officinalis L. (sage) extracts were studied.
Veličković Dragan T. +5 more
doaj +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
Influence of Processing on Bioactive Substances Content and Antioxidant Properties of Apple Purée from Organic and Conventional Production in Poland [PDF]
, 2007 The organic food market is developing dynamically in many European countries and therefore studies concerning the nutritive value of organically produced foods are becoming increasingly important.
Hallmann, Ewelina +2 more
core
Effects of olive and pomegranate by-products on human microbiota : a study using the SHIME (R) in vitro simulator [PDF]
, 2019 Two by-products containing phenols and polysaccharides, a "pate" (OP) from the extra virgin olive oil milling process and a decoction of pomegranate mesocarp (PM), were investigated for their effects on human microbiota using the SHIME (R) system.
Daghio, Matteo +6 more
core +1 more source
Phenolic compounds and carotenoids in pumpkin fruit and related traditional products [PDF]
Hemijska Industrija, 2016 Pumpkin fruit is used in a diet since ancient times especially in rural communities. The major contributory factors of nutritional and medicinal value of pumpkins are carotenoids, polysaccharides, vitamins, minerals, and phenolic compounds.
Zdunić Gordana M. +5 more
doaj +1 more source
American Journal of Public Health, 1921 The author states that a phenol coefficient indicates relative germicidal efficiency under laboratory conditions only, and has no practical value. Users of disinfectants ordinarily “follow directions,” and employ the dilutions recommended by the manufacturers.
openaire +4 more sources
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source