Results 31 to 40 of about 21,579,379 (182)
Genome-Wide Association Studies of the PR Interval in African Americans [PDF]
, 2011 The PR interval on the electrocardiogram reflects atrial and atrioventricular nodal conduction time. The PR interval is heritable, provides important information about arrhythmia risk, and has been suggested to differ among human races.Paltoo, Dina N., Smith, J Gustav, Smith, J.G., Heckbert, S.R., Zonderman, Alan B., Sotoodehnia, N., Mehra, R., Susan R. Heckbert, Ellinor, Patrick T, Palmer Cameron, Elsayed Z. Soliman, Benjamin, E.J., Newman, A.B., Müller, Martina, Kerr, K.F., Pfeufer, Arne, Newman, Anne B., Soliman, Elsayed Z, Magnani, JW, Candidate-gene Association Resource (CARe) Consortium, Ellinor Patrick T., Martina Müller, Kathleen F Kerr, Kerr, Kathleen F., Liu, Yongmei, Evans, Daniel S, Zonderman, Alan B, Palmer, C., Schnabel, Renate B, J Gustav Smith, Musani, Solomon K, Michele K Evans, Alonso Alvaro, Musani, Solomon K., Alonso, A, Newman, Anne B, Renate B Schnabel, Smith, JG, Smith, Gustav,, Schnabel Renate B., Magnani, Jared W., Emelia J Benjamin, null null, Ervin R Fox, Zonderman, AB, Jared W. Magnani, Paltoo, Dina N, Ellinor, Patrick T., Schnabel, R.B., Evans, M.K., Lund University., Kerr Kathleen F., Liu, Y, Cameron Palmer, Paltoo Dina N., Meng Yan A., Fox, Ervin R, Mehra Reena, Alonso, A., Patrick T. Ellinor, Anne B Newman, Redline Susan, Nalls, MA, Ellinor, PT, Schnabel, Renate B., Redline, Susan, Ellinor, P.T., Sotoodehnia, Nona, Nalls, Michael A., Arne Pfeufer, Smith J. Gustav, Newton-Cheh, Christopher, Solomon K Musani, Redline, S, Fox, ER, Renate B. Schnabel, Evans, Michele K., Mehra, R, Heckbert, SR, Meng, Yan A, Heckbert, Susan R, Christopher Newton-Cheh, Meng, YA, Evans, DS, Ervin R. Fox, Soliman Elsayed Z., Heckbert, Susan R., Michael A Nalls, Yan A. Meng, Fox, E.R., Susan Redline, Newton-Cheh Christopher, Fox, Ervin R., Evans, Michele K, Kathleen F. Kerr, Liu Yongmei, Alvaro Alonso, Nalls Michael A., Deo, R, Musani Solomon K., Newton-Cheh, C., Alan B. Zonderman, Soliman, EZ, Lubitz, S.A., Soliman, Elsayed Z., Dina N. Paltoo, Steven A Lubitz, Lubitz, SA, Alan B Zonderman, Evans, MK, Magnani, J.W., Patrick T Ellinor, Deo Rajat, Lubitz, Steven A, Nalls, Michael A, Pfeufer, A., Meng, Y.A., Evans Michele K., Benjamin, Emelia J., Benjamin Emelia J., Pfeufer Arne, Paltoo, D.N., Smith, J. Gustav, Sotoodehnia Nona, Elsayed Z Soliman, Soliman, E.Z., Jared W Magnani, Meng, Yan A., Redline, S., Newton-Cheh, C, Benjamin, Emelia J, Zonderman Alan B., Daniel S. Evans, Müller, M, Kerr, Kathleen F, Alonso, Alvaro, Rajat Deo, Kerr, KF, Schnabel, RB, Pfeufer, A, Müller, M., Paltoo, DN, Palmer, Cameron, Nona Sotoodehnia, Solomon K. Musani, Newman Anne B., Lubitz Steven A., Yongmei Liu, Zonderman, A.B., Nalls, M.A., Musani, S.K., Deo, Rajat, Musani, SK, Evans Daniel S., Deo, R., Dina N Paltoo, Newman, AB, Michele K. Evans, Mehra, Reena, Fox Ervin R., Yan A Meng, Evans, D.S., Evans, Daniel S., Benjamin, EJ, Susan R Heckbert, Emelia J. Benjamin, J. Gustav Smith, Reena Mehra, Palmer, C, Liu, Y., Magnani, Jared W, Anne B. Newman, Smith, Gustav, Daniel S Evans, Lubitz, Steven A., Steven A. Lubitz, Michael A. Nalls, Heckbert Susan R., Magnani Jared W., Müller Martina, Sotoodehnia, N, Smith, JG;Magnani, JW;Palmer, C;Meng, YA;Soliman, EZ;Musani, SK;Kerr, KF;Schnabel, RB;Lubitz, SA;Sotoodehnia, N;Redline, S;Pfeufer, A;Muller, M;Evans, DS;Nalls, MA;Liu, Y;Newman, AB;Zonderman, AB;Evans, MK;Deo, R;Ellinor, PT;Paltoo, DN;Newton-Cheh, C;Benjamin, EJ;Mehra, R;Alonso, A;Heckbert, SR;Fox, ER +181 morecore +1 more sourceGenome-Wide Identification of Rare and Common Variants Driving Triglyceride Levels in a Nevada Population
Frontiers in Genetics, 2021 Clinical conditions correlated with elevated triglyceride levels are well-known: coronary heart disease, hypertension, and diabetes. Underlying genetic and phenotypic mechanisms are not fully understood, partially due to lack of coordinated genotypic ...Robert W. Read, Karen A. Schlauch, Vincent C. Lombardi, Elizabeth T. Cirulli, Nicole L. Washington, James T. Lu, Joseph J. Grzymski, Joseph J. Grzymski +7 moredoaj +1 more sourceA phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank
Nature Communications, 2020 Depression is correlated with many brain-related traits. Here, Shen et al. perform phenome-wide association studies of a depression polygenic risk score (PRS) and find associations with 51 behavioural and 26 neuroimaging traits which are further followed Xueyi Shen, David M. Howard, Mark J. Adams, W. David Hill, Toni-Kim Clarke, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Ian J. Deary, Heather C. Whalley, Andrew M. McIntosh +8 moredoaj +1 more sourceThe Causal Relationships Between Extrinsic Exposures and Risk of Prostate Cancer: A Phenome-Wide Mendelian Randomization Study
Frontiers in Oncology, 2022 BackgroundProstate cancer is the second most common cancer in males worldwide, and multitudes of factors have been reported to be associated with prostate cancer risk.ObjectivesWe aim to conduct the phenome-wide exposed-omics analysis of the risk factors Dongqing Gu, Mingshuang Tang, Yutong Wang, Huijie Cui, Min Zhang, Ye Bai, Ziqian Zeng, Yunhua Tan, Xin Wang, Ben Zhang +9 moredoaj +1 more sourcePhenome-wide significant phenotypes in MGI identified using various PRS construction strategiesa.
, 2019 Phenome-wide significant phenotypes in MGI identified using various PRS construction strategiesa.Stephanie E. Moser (6836720), Bhramar Mukherjee (90346), Peter VandeHaar (6836696), Sarah A. Gagliano Taliun (6836708), Jonathon LeFaive (6836711), Thomas T. Klumpner (6836717), Erin O. Kaleba (6836714), Sachin Kheterpal (5538692), Robert B. Peng (6836699), Sayantan Das (1734532), Lauren J. Beesley (6836693), Stephen B. Gruber (108155), Maxwell Salvatore (6836702), Matthew Zawistowski (6836705), Lars G. Fritsche (162272), Victoria M. Blanc (6836723), Chad M. Brummett (6338336), Gonçalo R. Abecasis (36598) +17 morecore +1 more sourceThe extracellular matrix phenome across species
Matrix Biology Plus, 2020 Extracellular matrices are essential for cellular and organismal function. Recent genome-wide and phenome-wide association studies started to reveal a broad spectrum of phenotypes associated with genetic variants.Cyril Statzer, Collin Y. Ewalddoaj +1 more sourceGenome-Wide Association Studies of Asthma in Population-Based Cohorts Confirm Known and Suggested Loci and Identify an Additional Association near HLA [PDF]
, 2012 Rationale: Asthma has substantial morbidity and mortality and a strong genetic component, but identification of genetic risk factors is limited by availability of suitable studies.Palmer Cameron D., Marjo-Riitta Jarvelin, Coin, Lachlan, Matthew A. Brown (131482), Ferreira, Manuel, O'Connor, George T, Guy B Marks, Dharmage, Shyamali C, Adaikalavan Ramasamy (4841), Anneli Pouta, Lehtimäki Terho, Tari Haahtela, Veikko Salomaa (62543), Shyamali C. Dharmage, Manuel A R Ferreira, Lehtimaki, Terho, Anneli Pouta (116626), Pekkanen Juha, Joel N Hirschhorn, Gajdos, Zofia K, Strachan David P., Palotie Aarno, Colin F. Robertson (131511), Philip J Thompson, Lehtimäki, T, Montgomery, Grant, Andrew C. Heath, Duffy David L., Strachan, David P, Elisabeth Widen (75580), Matthias Wjst (56613), Thompson, Philip, David L. Duffy (131489), Martin, Nicholas G., Laitinen, Tarja, Hirschhorn, Joel, Raitakari, Olli T, Alexessander Couto Alves, Tarja Laitinen, Lyon, Helen, Wareham, Nick, Laitinen Tarja, Palmer, CD, Raitakari Olli T., Peter Le Souef, Christer Janson, Vedantam, Sailaja, Janson Christer, Sailaja Vedantam (131467), George T. O'Connor (110263), Marks Guy B., Ramasamy, Adaikalavan, Ferreira, Manuel AR, Andrew C Heath, Peter Le Souef (131503), David P Strachan, Palotie, Aarno, Eriksson, Johan, Jing Hua Zhao (73808), Jorma Viikari, Tari Haahtela (131492), Nick Wareham, Grant W. Montgomery (131518), Heathe, Andrew C, Khaw, KT, Nicholas G. Martin (113568), Jarvelin, Marjo-Riitta, Robertson, CF, Mika Kähönen (131499), Michael J. Abramson, Matheson, M C, Kay-Tee Khaw, Pouta, Anneli, David P. Strachan, Abramson, Michael J, Manuel A. R. Ferreira, Aarno Palotie (41342), Juha Pekkanen (27303), Palotie, A, Mikko Kuokkanen, Ferreira, MA, Marks, Guy B., Helen N Lyon, Philip J. Thompson (131523), Cameron D Palmer, Deborah L. Jarvis (131514), Thompson, Philip J., Colin F. Robertson, Janson, Christer,, Heath, Andrew C, Madden, Pamela AF, Kuokkanen Mikko, Strachan, David P., Salomaa, Veikko, Jaana Laitinen (116629), Coin, L, Haahtela, T, Widen Elisabeth, Ramasamy, A, Martin, NG, Janson, C, Madden, PA, Eriksson, J, Laitinen Jaana, Thompson Philip J., Couto Alves, A, Matheson, Melanie C, Australian Asthma Genetics, Martin Nicholas G., ?, ?, Salomaa, V, Zhao, Jing Hua, Olli T Raitakari, Palmer, Cameron D, David L Duffy, Jarvis Deborah L., Palmer, Cameron, Widen, Elizabeth, Zofia K. Gajdos (131468), Matheson, Melanie C., Widen, Elisabeth, O'Connor George T., Martin, Nicholas, Raitakari, OT, O'Connor, George, Kähönen Mika, Colin F Robertson, O'Connor, GT, Kähönen, M, Gajdos, Zofia, Duffy, David L., Lachlan Coin (3863), Jarvelin Marjo-Riitta, Dharmage Shyamali C., Dharmage, Shyamali C., Raitakari, Olli T., Jousilahti, P, Hirschhorn Joel N., Pekka Jousilahti, Ferreira Manuel A. R., Lyon, Helen N., Guy B. Marks (116572), Martin, Nicholas G, Nicholas G Martin, Brown, MA, Marks, Guy, Michael J. Abramson (131480), Pekkanen, Juha, Lyon, HN, Matheson Melanie C., Pekkanen, J, Madden Pamela A. F., Duffy, DL, Heath, AC, Gajdos Zofia K., Olli T. Raitakari (115559), Lachlan Coin, Lyon, Helen N, Camerond Palmer, Nicholas G. Martin, Strachan, David, Jousilahti Pekka, Jousilahti, Pekka, Dharmage, Shyamali, Pamela A. F. Madden (127156), Veikko Salomaa, Madden, Pamela, Wjst Matthias, Zofia K. Gajdos, Marks, GB, Matthew A Brown, Manuel A. R. Ferreira (131476), Khaw, Kay-Tee, Jarvis, Deborah L., Kahonen, Mika, Montgomery, GW, Montgomery, Grant W, Eriksson Johan, Pouta, A, Viikari, J, Heath Andrew C., Johan Eriksson, Shyamali C. Dharmage (131486), Laitinen, T, Laitinen, J, Johan Eriksson (131534), Pekka Jousilahti (131538), David L. Duffy, Palmer, Cameron D., Palmer, Cameron Douglas, George T O'Connor, Duffy, David, Viikari, E, Jaana Laitinen, Kay-Tee Khaw (110271), Viikari Jorma, Matheson, MC, Mikko Kuokkanen (131465), Khaw Kay-Tee, Matthew A. Brown, Thompson, Philip J, Montgomery Grant W., Le Souef, P, Robertson, Colin, Jarvis, Debbie, Mika Kähönen, Pamela A F Madden, Melanie C Matheson, Pouta Anneli, Alexessander Couto Alves (131470), Andrew C. Heath (127152), Tarja Laitinen (131542), George T. O’connor, Viikari, Jorma, Aarno Palotie, O'Connor, George T., Melanie C. Matheson (131507), Lyon Helen N., Marks, Guy B, Joel N. Hirschhorn, Ramasamy Adaikalavan, Terho Lehtimäki (49739), Juha Pekkanen, Marjo-Riitta Jarvelin (110290), Heathe, Andrew, Abramson Michael J., Heath, Andrew C., Wareham Nick, Gajdos, ZK, Zhao, Jing, Brown, Matthew A, Deborah L. Jarvis, Matheson, M, Abramson, Michael, Michael J Abramson, Christer Janson (83414), Jarvelin, MR, Adaikalavan Ramasamy, Duffy, David L, Jing Hua Zhao, Zhao Jing Hua, Jorma Viikari (49741), Montgomery, Grant W., Brown, Matthew A., Vedantam Sailaja, Robertson Colin F., Wjst, Matthias, Cameron D. Palmer (131509), David P. Strachan (110302), Hirschhorn, Joel N., Ferreira, Manuel A. R., Er Couto Alves, Thompson, PJ, Raitakari, Olli, Brown, Matthew, Laitinen, Jaana, Haahtela Tari, Grant W Montgomery, Brown Matthew A., Alves, Alexessander Couto, Robertson, Colin F., Matthias Wjst, Olli T. Raitakari, Zhao, JH, Couto Alves, Alexessander, Shyamali C Dharmage, Melanie C. Matheson, Gajdos, Zofia K., Kuokkanen, M, Widen, E, Hirschhorn, Joel N, Salomaa Veikko, Deborah L Jarvis, Janson, Christer, Guyb. Marks, Le Souef, Peter, Le Souef Peter, Wareham, N, Haahtela, Tari, Kuokkanen, Mikko, Hirschhorn, JN, Vedantam, S, Dharmage, SC, Jarvis, DL, Jarvis, Deborah L, Couto Alves Alexessander, Strachan, DP, Nick Wareham (131528), Pamela A. F. Madden, Abramson, MJ, Coin Lachlan, Elisabeth Widen, Madden, Pamela A, Zofia K Gajdos, Wjst, M, Sailaja Vedantam, Grant W. Montgomery, Robertson, Colin F, Philip J. Thompson, Helen N. Lyon (131473), Australian Asthma Genetics Consortium Collaborators, Abramson, Michael J., Joel N. Hirschhorn (131545), Terho Lehtimäki, Helen N. Lyon, Madden, Pamela A. F., Strachan, D. P., Jousilahti, P., Raitakari, O. T., Thompson, P. J., Lehtimäki, T., Salomaa, V., Dharmage, S. C., Montgomery, G. W., Widen, E., Gajdos, Z. K., O'Connor, G. T., Couto Alves, A., Eriksson, J., Laitinen, T., Vedantam, S., Haahtela, T., Heath, A. C., et al,, et al., Pouta, A., Hirschhorn, J. N., Abramson, M. J., Palotie, A., Duffy, D. L., Viikari, J., Jarvelin, M. R., Kähönen, M., Brown, Matthew. A., Wjst, M., Kuokkanen, M., Coin, L., Lyon, H. N., Matheson, M. C., Palmer, C. D., Khaw, K. T., Ferreira, M. A. R., Le Souef, P., Martin, N. G., Robertson, C. F., Wareham, N., Janson, C., Pekkanen, J., Madden, P. A. F., Zhao, J. H., Jarvis, D. L., Laitinen, J., Marks, G. B., Ramasamy, A. +353 morecore +3 more sources
