Results 1 to 10 of about 30,931 (193)

Phenome-Wide Association Studies Between SERINC2 and Neuropsychiatric Disorders

Frontiers in Psychiatry
ObjectivesSERINC2 has been associated with alcoholism, bipolar disorder and autism, but the comparability and specificity issues of the findings remain unaddressed.
Jiawu Ji, Ruilan Yang
exaly   +3 more sources

Unique Attributes of the Laurel Wilt Fungal Pathogen, Raffaelea lauricola, as Revealed by Metabolic Profiling

Pathogens, 2021
Raffaelea lauricola is the causative agent of laurel wilt, a devastating disease of lauraceous trees. R. lauricola is also an obligate nutritional symbiont of several ambrosia beetle species who act as vectors for the pathogen.
Ross Joseph, Michelle Lasa, Yonghong Zhou, Nemat O. Keyhani   +3 more
doaj   +1 more source

Ibero-American Endometriosis Patient Phenome: Demographics, Obstetric-Gynecologic Traits, and Symptomatology

Frontiers in Reproductive Health, 2021
Background: An international collaborative study was conducted to determine the demographic and clinical profiles of Hispanic/Latinx endometriosis patients from Latin America and Spain using the Minimal Clinical Questionnaire developed by the World ...
Idhaliz Flores-Caldera, Idhaliz Flores-Caldera, Paola M. Ramos-Echevarría, José A. Oliveras-Torres, Natasha Santos-Piñero, Estefanía D. Rivera-Mudafort, Denisse M. Soto-Soto, Denisse M. Soto-Soto, Brian Hernández-Colón, Luis E. Rivera-Hiraldo, Loraine Mas, Mary Rodríguez-Rabassa, Nabal J. Bracero, Edgardo Rolla, Edgardo Rolla, Ibero-American Endometriosis Association   +15 more
doaj   +1 more source

Phenomic Analysis of Chronic Granulomatous Disease Reveals More Severe Integumentary Infections in X-Linked Compared With Autosomal Recessive Chronic Granulomatous Disease

Frontiers in Immunology, 2022
BackgroundChronic granulomatous disease (CGD) is an inborn error of immunity (IEI), characterised by recurrent bacterial and fungal infections. It is inherited either in an X-linked (XL) or autosomal recessive (AR) mode.
Timothy Lok-Hin Chiu, Daniel Leung, Koon-Wing Chan, Hok Man Yeung, Chung-Yin Wong, Huawei Mao, Jianxin He, Pandiarajan Vignesh, Weiling Liang, Woei Kang Liew, Li-Ping Jiang, Tong-Xin Chen, Xiang-Yuan Chen, Yin-Bo Tao, Yong-Bin Xu, Hsin-Hui Yu, Alta Terblanche, David Christopher Lung, Cheng-Rong Li, Jing Chen, Man Tian, Brian Eley, Xingtian Yang, Jing Yang, Wen Chin Chiang, Bee Wah Lee, Bee Wah Lee, Deepti Suri, Amit Rawat, Anju Gupta, Surjit Singh, Wilfred Hing Sang Wong, Gilbert T. Chua, Jaime Sou Da Rosa Duque, Kai-Ning Cheong, Patrick Chun-Yin Chong, Marco Hok-Kung Ho, Tsz-Leung Lee, Wanling Yang, Pamela P. Lee, Yu Lung Lau   +40 more
doaj   +1 more source

The Human Extracellular Matrix Diseasome Reveals Genotype–Phenotype Associations with Clinical Implications for Age-Related Diseases

Biomedicines, 2023
The extracellular matrix (ECM) is earning an increasingly relevant role in many disease states and aging. The analysis of these disease states is possible with the GWAS and PheWAS methodologies, and through our analysis, we aimed to explore the ...
Cyril Statzer, Karan Luthria, Arastu Sharma, Maricel G. Kann, Collin Y. Ewald   +4 more
doaj   +1 more source

Phenome-wide and genome-wide analyses of quality of life in schizophrenia

BJPsych Open, 2021
Background Schizophrenia negatively affects quality of life (QoL). A handful of variables from small studies have been reported to influence QoL in patients with schizophrenia, but a study comprehensively dissecting the genetic and non-genetic ...
Raha Pazoki, Bochao Danae Lin, Kristel R. van Eijk, Dick Schijven, Sonja de Zwarte, Sinan Guloksuz, Jurjen J. Luykx   +6 more
doaj   +1 more source

Single cell metabolic phenome and genome via the ramanome technology platform: Precision medicine of infectious diseases at the ultimate precision?

iLABMED, 2023
Due to the limitations of existing approaches, a rapid, sensitive, accurate, comprehensive, and generally applicable strategy to diagnose and treat bacterial and fungal infections remains a major challenge. Here, based on the ramanome technology platform,
Jian Xu, Jianzhong Zhang, Yingchun Xu, Yi‐Wei Tang, Bo Ma, Yuzhang Wu   +5 more
doaj   +1 more source

A Phenome-Wide Association Study of the Effects of Fusarium graminearum Transcription Factors on Fusarium Graminearum Virus 1 Infection

Frontiers in Microbiology, 2021
The Fusarium graminearum virus 1 (FgV1) causes noticeable phenotypic changes such as reduced mycelial growth, increase pigmentation, and reduced pathogenicity in its host fungi, Fusarium graminearum. Previous study showed that the numerous F. graminearum
Jisuk Yu, Kook-Hyung Kim, Kook-Hyung Kim, Kook-Hyung Kim   +3 more
doaj   +1 more source

Genome-Wide Association Studies of Soybean Yield-Related Hyperspectral Reflectance Bands Using Machine Learning-Mediated Data Integration Methods

Frontiers in Plant Science, 2021
In conjunction with big data analysis methods, plant omics technologies have provided scientists with cost-effective and promising tools for discovering genetic architectures of complex agronomic traits using large breeding populations.
Mohsen Yoosefzadeh-Najafabadi, Sepideh Torabi, Dan Tulpan, Istvan Rajcan, Milad Eskandari   +4 more
doaj   +1 more source

Visual Analysis for Detection and Quantification of Pseudomonas cichorii Disease Severity in Tomato Plants

The Plant Pathology Journal, 2016
Pathogen infection in plants induces complex responses ranging from gene expression to metabolic processes in infected plants. In spite of many studies on biotic stress-related changes in host plants, little is known about the metabolic and phenotypic ...
Dhinesh Kumar Rajendran, Eunsoo Park, Rajalingam Nagendran, Nguyen Bao Hung, Byoung-Kwan Cho, Kyung-Hwan Kim, Yong Hoon Lee   +6 more
doaj   +1 more source