Results 31 to 40 of about 27,998 (235)

Phenome-wide association study results of monounsaturated fatty acids (MUFAs) genetic risk score. [PDF]

, 2022
(XLSX)
Dipender Gill (5514923), Loukas Zagkos (14309460), Abbas Dehghan (174878), Fotios Koskeridis (6861581), Rui Pinto (832195), Fotios Drenos (113686), Paul Elliott (27295), Ioanna Tzoulaki (257920), Verena Zuber (719156), Marie-Joe Dib (12000806), Georgios Markozannes (4406458), Kostas Tsilidis (2590939)   +11 more
core   +1 more source

Mapping gene associations in human mitochondria using clinical disease phenotypes [PDF]

, 2009
Nuclear genes encode most mitochondrial proteins, and their mutations cause diverse and debilitating clinical disorders. To date, 1,200 of these mitochondrial genes have been recorded, while no standardized catalog exists of the associated clinical ...
Curt Scharfe, Allen, Edward A., Enns, Gregory M., Guan-Cheng Li, Henry Horng-Shing Lu, Lu, Henry Horng-Shing, Neuenburg, Jutta K., Ronald W. Davis, Jutta K Neuenburg, Tina M. Cowan, Cowan, Tina M., Thomas Klopstock, Jutta K. Neuenburg, Klopstock, Thomas, Tina M Cowan, Scharfe, Curt, Li, Guan-Cheng, Edward A Allen, Ronald W Davis, Edward A. Allen, Davis, Ronald W., Gregory M Enns, Gregory M. Enns   +22 more
core   +1 more source

Phenome-wide association study results of saturated fatty acids (SFAs) genetic risk score. [PDF]

, 2022
(XLSX)
Dipender Gill (5514923), Loukas Zagkos (14309460), Abbas Dehghan (174878), Fotios Koskeridis (6861581), Rui Pinto (832195), Fotios Drenos (113686), Paul Elliott (27295), Ioanna Tzoulaki (257920), Verena Zuber (719156), Marie-Joe Dib (12000806), Georgios Markozannes (4406458), Kostas Tsilidis (2590939)   +11 more
core   +1 more source

Association of immunity markers with the risk of incident frailty: the Rugao longitudinal aging study

Immunity & Ageing, 2022
Background The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR) and systemic immune-inflammation index (SII) are readily available circulatory immunity markers that are associated with components of frailty.
Hui Zhang, Meng Hao, Zixin Hu, Yi Li, Xiaoyan Jiang, Jiucun Wang, Li Jin, Zuyun Liu, Xiaofeng Wang, Xuehui Sun   +9 more
doaj   +1 more source

List of urine analytes from National Phenome Centre [PDF]

, 2021
List of all Barwon Infant Study urine analytes currently available, and potentially available from Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS) from the Australian National Phenome Centre (NPC) at Murdoch University, Western ...
James Hedley (9598800)
core   +1 more source

Histone Methyltransferase Dot1L Contributes to RIPK1 Kinase‐Dependent Apoptosis in Cerebral Ischemia/Reperfusion

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background Neuron apoptosis is a pivotal process for brain damage in cerebral ischemia. Dot1L (disruptor of telomeric silencing 1‐like) is only known histone H3K79 methyltransferase.
Jinghuan Wang, Wen Zhong, Haibi Su, Jie Xu, Di Yang, Xinhua Liu, Yi Zhun Zhu   +6 more
doaj   +1 more source

Phenome-wide association study results of polyunsaturated fatty acids (PUFAs) genetic risk score. [PDF]

, 2022
(XLSX)
Dipender Gill (5514923), Loukas Zagkos (14309460), Abbas Dehghan (174878), Fotios Koskeridis (6861581), Rui Pinto (832195), Fotios Drenos (113686), Paul Elliott (27295), Ioanna Tzoulaki (257920), Verena Zuber (719156), Marie-Joe Dib (12000806), Georgios Markozannes (4406458), Kostas Tsilidis (2590939)   +11 more
core   +1 more source

Inhibition of the cardiac fibroblast-enriched histone methyltransferase Dot1L prevents cardiac fibrosis and cardiac dysfunction

Cell & Bioscience, 2022
Background Cardiac fibrosis is characterized by excessive extracellular matrix deposition that contributes to compromised cardiac function and potentially heart failure. Disruptor of telomeric silencing 1-like (Dot1L) is the catalytic enzyme required for
Jie Xu, Jinghuan Wang, Fen Long, Wen Zhong, Haibi Su, Zhenghua Su, Xinhua Liu   +6 more
doaj   +1 more source

Phenome-wide association study results of docosahexaenoic acid (DHA) genetic risk score. [PDF]

, 2022
(XLSX)
Dipender Gill (5514923), Loukas Zagkos (14309460), Abbas Dehghan (174878), Fotios Koskeridis (6861581), Rui Pinto (832195), Fotios Drenos (113686), Paul Elliott (27295), Ioanna Tzoulaki (257920), Verena Zuber (719156), Marie-Joe Dib (12000806), Georgios Markozannes (4406458), Kostas Tsilidis (2590939)   +11 more
core   +1 more source

Methodology in phenome-wide association studies:a systematic review [PDF]

, 2021
Phenome-wide association study (PheWAS) has been increasingly used to identify novel genetic associations across a wide spectrum of phenotypes. This systematic review aims to summarise the PheWAS methodology, discuss the advantages and challenges of ...
Zhang, Xiaomeng, Meng, Xiangrui, Georgiou, Andrea, Li, Xue, Yu, Lili, Theodoratou, Evropi; id_orcid, Campbell, Harry; id_orcid, Koskeridis, Fotios, Wang, Lijuan   +8 more
core   +1 more source