Results 61 to 70 of about 832,396 (367)

Dynamic effects of interacting genes underlying rice flowering-time phenotypic plasticity and global adaptation

Genome Research, 2020
The phenotypic variation of living organisms is shaped by genetics, environment, and their interaction. Understanding phenotypic plasticity under natural conditions is hindered by the apparently complex environment and the interacting genes and pathways.
Tingting Guo, Qi Mu, Jinyu Wang, Adam E Vanous, A. Onogi, H. Iwata, Xianran Li, Jianming Yu   +7 more
semanticscholar   +1 more source

The New Nitric Oxide Donor, FOR 911B, Induces Relaxation in Isolated Rat Aorta Involving the NO/sGC/cGMP Pathway and K⁺ Channels

Receptors
Background: Nitric oxide (NO) is a gaseous molecule considered to be a protagonist in the dilation of blood vessels, and its property and/or bioavailability are reduced in pathophysiological conditions such as cardiovascular diseases.
Mirelly Cunha da Silva, Florêncio Sousa Gouveia Júnior, Thyago Moreira de Queiroz   +2 more
doaj   +1 more source

Phenotypic robustness can increase phenotypic variability after non-genetic perturbations in gene regulatory circuits [PDF]

, 2010
Non-genetic perturbations, such as environmental change or developmental noise, can induce novel phenotypes. If an induced phenotype confers a fitness advantage, selection may promote its genetic stabilization. Non-genetic perturbations can thus initiate
Ancel, Aubret, Azevedo, Bergman, Ciliberti, Ciliberti, Cooper, Davidson, de Jong, de Visser, Draghi, Draghi, Eldar, Elowitz, Espinosa-Soto, Espinosa-Soto, Ferrada, Fraser, Gibson, Gilbert, Gomez-Mestre, Griswold, Hall, Hermisson, Kim, Kimbrell, Kondrashov, Lande, Ledon-Rettig, Lehner, Levy, Lipman, Martin, Martin, Masel, Masel, Masel, McAdams, Meiklejohn, Moczek, Newman, Orr, Palmer, Palmer, Pigliucci, Pigliucci, Price, Proulx, Prud'homme, Raj, Rice, Roberts, Rodrigues, Rutherford, Schmalhausen, Schultes, Schuster, Shubin, Siegal, Snell-Rood, Sollars, Suzuki, Tirosh, van Nimwegen, Waddington, Waddington, Wagner, Wagner, Wagner, Wagner, Wagner, West-Eberhard, West-Eberhard, Wray   +73 more
core   +3 more sources

New Insights Into the Role of Phenotypic Plasticity and EMT in Driving Cancer Progression

Frontiers in Molecular Biosciences, 2020
Tumor cells demonstrate substantial plasticity in their genotypic and phenotypic characteristics. Epithelial-mesenchymal plasticity (EMP) can be characterized into dynamic intermediate states and can be orchestrated by many factors, either ...
Sugandha Bhatia, Peiyu Wang, A. Toh, E. Thompson   +3 more
semanticscholar   +1 more source

Cardiovascular and Renal Effects Induced by Alpha-Lipoic Acid Treatment in Two-Kidney-One-Clip Hypertensive Rats

Biomedicines
α-Lipoic acid (LA) is an antioxidant of endogenous production, also obtained exogenously. Oxidative stress is closely associated with hypertension, which causes kidney injury and endothelial dysfunction.
Déborah Victória Gomes Nascimento, Darlyson Ferreira Alencar, Matheus Vinicius Barbosa da Silva, Danilo Galvão Rocha, Camila Ferreira Roncari, Roberta Jeane Bezerra Jorge, Renata de Sousa Alves, Richard Boarato David, Wylla Tatiana Ferreira e Silva, Lígia Cristina Monteiro Galindo, Thyago Moreira de Queiroz   +10 more
doaj   +1 more source

Plasticity leaves a phenotypic signature during local adaptation

Evolution Letters, 2020
Phenotypic responses to a novel or extreme environment are initially plastic, only later to be followed by genetic change. Whether or not environmentally induced phenotypes are sufficiently recurrent and fit to leave a signature in adaptive evolution is ...
Reinder Radersma, Daniel W.A. Noble, Tobias Uller   +2 more
doaj   +1 more source

Eco-evolutionary dynamics in fragmented landscapes [PDF]

, 2017
Peer ...
Altermatt, Astegiano, Baguette, Baguette, Baguette, Becks, Bell, Bell, Bestion, Bestion, Bitume, Blanquart, Bocedi, Bocedi, Bonduriansky, Bonte, Burgess, Carazo, Cheptou, Cheviron, Clobert, Clobert, Clobert, Cook, Cote, Crespi, Cushman, Darwin, De Meester, Delgado, DiBattista, DiBattista, Dixo, Dobzhansky, Duputié, Edelaar, Edelaar, Ellner, Evans, Fahrig, Farkas, Farkas, Farkas, Fontúrbel, Frank, Fronhofer, Fronhofer, Fukami, Fussmann, Galtier, Gandon, Gandon, Garant, Garel, Ghalambor, Gomulkiewicz, Gomulkiewicz, Guillaume, Guillaume, Gyllenberg, Haddad, Haddad, Hand, Hanski, Hanski, Hanski, Hanski, Hanski, Hanski, Hanski, Hanski, Hartl, Hassell, Hendry, Hendry, Hendry, Hendry, Henry, Higgins, Holt, Holt, Holt, Hughes, Jacob, Kawecki, Keymer, Kinnison, Kronholm, Kubisch, Laughlin, Lechowicz, Legrand, Legrand, Legrand, Leibold, Leimu, Lenormand, Lewontin, Li, Li, Lohr, Lohr, Lopez, Low-Décarie, Lynch, Manel, Massot, Meester, Morris, Mouquet, Nadeau, Nee, North, Nosil, Orsini, Orsini, Pearse, Pelletier, Perrin, Phillips, Poethke, Poethke, Poethke, Post, Ravigné, Ravigné, Riba, Richardson, Ritchie, Robert, Robinson, Rodrigues, Roissart, Ronce, Ronce, Ronce, Rousset, Räsänen, Saastamoinen, Scheiner, Schoener, Schtickzelle, Schtickzelle, Shefferson, Shine, Stapley, Tack, Taylor, Taylor, Travis, Travis, Trochet, Turner, Urban, Urban, Vellend, Walser, Wheat, Wiegand, Wiens, Wilcove, Yeaman, Yoshida, Zheng   +163 more
core   +3 more sources

ΔTraitSDMs: species distribution models that account for local adaptation and phenotypic plasticity.

New Phytologist, 2019
Improving our understanding of species ranges under rapid climate change requires application of our knowledge of the tolerance and adaptive capacity of populations to changing environmental conditions.
Marta Benito Garzón, T. Robson, A. Hampe   +2 more
semanticscholar   +1 more source

Phenotypic plasticity and experimental evolution [PDF]

Journal of Experimental Biology, 2006
SUMMARYNatural or artificial selection that favors higher values of a particular trait within a given population should engender an evolutionary response that increases the mean value of the trait. For this prediction to hold, the phenotypic variance of the trait must be caused in part by additive effects of alleles segregating in the population, and ...
Theodore, Garland, Scott A, Kelly
openaire   +3 more sources

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source