Results 71 to 80 of about 832,396 (367)

The role of forest genetic resources in responding to biotic and abiotic factors in the context of anthropogenic climate change [PDF]

, 2015
The current distribution of forest genetic resources on Earth is the result of a combination of natural processes and human actions. Over time, tree populations have become adapted to their habitats including the local ecological disturbances they face ...
Alfaro, R.I., Baldinelli, G., Dawson, Ian K., El-Kassaby, Y.A., Fady, B., Fleming, R.A., Lindig-Cisneros, R.A., Loo, J., Murdock, T., Navarro, C.M., Saenz-Romero, C., Skroppa, T., Vendramin, G.G., Vinceti, B.   +13 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Impact of Early-Life Brain Injury on Gut Microbiota Composition in Rodents: Systematic Review with Implications for Neurodevelopment

Cells
Early-life brain injuries are major causes of long-term neurodevelopmental disorders such as cerebral palsy. Emerging evidence suggests these injuries can alter the gut microbiota composition, intestinal integrity, and neuroinflammatory responses.
Vanessa da Silva Souza, Raul Manhães-de-Castro, Sabrina da Conceição Pereira, Beatriz Souza de Silveira, Caio Matheus Santos da Silva Calado, Henrique José Cavalcanti Bezerra Gouveia, Jacques-Olivier Coq, Ana Elisa Toscano   +7 more
doaj   +1 more source

Functional Mapping of Phenotypic Plasticity of Staphylococcus aureus Under Vancomycin Pressure

Frontiers in Microbiology, 2021
Phenotypic plasticity is the exhibition of various phenotypic traits produced by a single genotype in response to environmental changes, enabling organisms to adapt to environmental changes by maintaining growth and reproduction. Despite its significance
Dengcheng Yang, Xuyang Zheng, Libo Jiang, Libo Jiang, Meixia Ye, Meixia Ye, Xiaoqing He, Xiaoqing He, Yi Jin, Yi Jin, Rongling Wu, Rongling Wu, Rongling Wu   +12 more
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Fasting and postprandial Ghrelin levels in Parkinson’s disease: a systematic review and meta-analysis

npj Parkinson's Disease
Parkinson’s disease (PD) is a progressive movement disorder with motor and non-motor symptoms, including gastrointestinal and olfactory dysfunctions. These symptoms may be associated with plasma concentrations of the hormone ghrelin.
Henrique José Cavalcanti Bezerra Gouveia, Osmar Henrique dos Santos-Júnior, Johannes Frasnelli   +2 more
doaj   +1 more source

Cancer cells exhibit clonal diversity in phenotypic plasticity [PDF]

Open Biology, 2017
Phenotypic heterogeneity in cancers is associated with invasive progression and drug resistance. This heterogeneity arises in part from the ability of cancer cells to switch between phenotypic states, but the dynamics of this cellular plasticity remain ...
Robert Austin Mathis, Ethan S. Sokol, Piyush B. Gupta   +2 more
doaj   +1 more source

How to analyse plant phenotypic plasticity in response to a changing climate.

New Phytologist, 2019
Contents Summary 1235 I. Introduction 1235 II. The many shapes of phenotypic plasticity 1236 III. Random regression mixed model framework 1237 IV. Conclusions 1240 Acknowledgements 1240 References 1240 SUMMARY: Plant biology is experiencing a renewed ...
P. Arnold, L. Kruuk, A. Nicotra
semanticscholar   +1 more source

Intraspecific variation in Phragmites australis: Clinal adaption of functional traits and phenotypic plasticity vary with latitude of origin

Journal of Ecology, 2020
Widespread plant species generally have high intraspecific variation in functional traits, which is reflected in their great variety of phenotypes. This variety can result from both genetic differences due to local adaptation and phenotypic plasticity ...
Linjing Ren, Xiao Guo, Shuna Liu, T. Yu, Weihua Guo, Ren-qing Wang, S. Ye, C. Lambertini, H. Brix, Franziska Eller   +9 more
semanticscholar   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source