Results 31 to 40 of about 92,765 (376)
Jundishapur journal of health sciences, 2019 Background: Phenytoin is one of the most important chemical drugs used for the treatment of skin wound. Objectives: In the present study, the molecular effect of phenytoin on the expression of VEGF and TGF-β genes was investigated.
Roghaye Savari +3 more
semanticscholar +1 more source
Indian Journal of Anaesthesia, 2017 Background and Aims: Patients with intracranial tumour are usually on anticonvulsants. Patients on phenytoin therapy demonstrate rapid metabolism of nondepolarising muscle relaxants secondary to enzyme induction.
Veena Sheshadri +3 more
doaj +1 more source
Phenytoin Toxicity with High Dose, Concomitant Ascorbic Acid Dosing
INNOVATIONS in Pharmacy, 2022 High dose ascorbic acid may increase risk of phenytoin toxicity. This case report demonstrates high phenytoin levels resulting in adverse drug reactions subsequent to dosing concomitantly with high dose vitamin C, or ascorbic acid (AA), as a precaution ...
Michael J. Schuh +2 more
doaj +1 more source
Pharmacogenomic testing and its future in community pharmacy [PDF]
, 2020 Although it is common to see pharmacogenomic testing used North America and Australia, it is not yet part of practice in the UK. With the promise of genomic screening becoming part of the NHS, pharmacists must equip themselves with a knowledge of how the
Wright, David, Youssef, Essra
core +1 more source
A role for fast rhythmic bursting neurons in cortical gamma oscillations in vitro [PDF]
, 2004 Basic cellular and network mechanisms underlying gamma frequency oscillations (30–80 Hz) have been well characterized in the hippocampus and associated structures.
A. Bibbig +33 more
core +3 more sources
CYP2C9 polymorphisms are associated with phenytoin toxicity in South-Indian epileptic patients
Journal of Dr. NTR University of Health Sciences, 2020 Background and Aims: The contribution of CYP2C9 in phenytoin metabolism is generally modest, but it increases with increasing serum phenytoin concentration.
Rakesh Reddy Reddigari +4 more
doaj +1 more source
IV Levetiracetam versus IV Phenytoin in Childhood Seizures: A Randomized Controlled Trial
Journal of Pediatric Neurosciences, 2018 Objectives: To compare the efficacy of IV phenytoin and IV levetiracetam in acute seizures. Design: Randomized controlled trial. Setting: Tertiary care hospital, November 2012 to April 2014.
Kanika Singh +3 more
semanticscholar +1 more source
Acute Phenytoin Intoxication: Causes, Symptoms, Misdiagnoses, and Outcomes
Kaohsiung Journal of Medical Sciences, 2004 Phenytoin is a commonly prescribed antiepileptic drug. Due to its saturation (zero-order) pharmacokinetics, phenytoin carries a special risk of dose-related toxicity that is an important issue in emergency medicine.
Wen-Juh Hwang, Jing-Jane Tsai
doaj +1 more source
Phenytoin regulates osteogenic differentiation of human bone marrow stem cells by PI3K/Akt pathway
Regenerative Therapy, 2023 Background: We mainly studied the mechanism by which phenytoin promotes osteogenic differentiation of human jawbone marrow stem cells. Methods: Bone marrow stem cells were extracted from jaw bone tissue debris obtained from 5 subjects undergoing implant ...
Zeliang Zhang +3 more
doaj +1 more source
Searching for New Leads to Treat Epilepsy: Target-Based Virtual Screening for the Discovery of Anticonvulsant Agents [PDF]
, 2018 The purpose of this investigation is to contribute to the development of new anticonvulsant drugs to treat patients with refractory epilepsy. We applied a virtual screening protocol that involved the search into molecular databases of new compounds and ...
Bruno Blanch, Luis Enrique +8 more
core +2 more sources