Results 71 to 80 of about 92,765 (376)

Gingival enlargement following levetiracetam treatment: A clinical case analysis

Epilepsia Open, EarlyView.
Abstract This report describes a 21‐year‐old female with a history of epilepsy, diagnosed at age 17, who developed gingival enlargement after being treated with levetiracetam. Her dosage was titrated to 750 mg twice daily, achieving satisfactory seizure control.
Awadh M. Alahmari, Ali M. Alkhathaami
wiley   +1 more source

Effectiveness and safety of early add‐on therapy with brivaracetam in patients with poorly controlled focal seizures in routine clinical practice: BRIV‐add study

Epilepsia Open, EarlyView.
Abstract Objective To evaluate the effectiveness and safety of brivaracetam (BRV) as an add‐on therapy in patients with focal onset seizures who did not achieve seizure freedom with antiseizure medication (ASM) monotherapy in routine clinical practice.
Pedro J. Serrano‐Castro, Fernando Caballero‐Martínez, Francisco J. Campos‐Lucas, Daniel Campos‐Fernández, María José de Aguilar‐Amat, Alberto García, Ariadna Gifreu, Irene Santamaría‐Rodríguez, Juan José Poza, Manuel Toledo‐Argany, Grupo de Investigadores Colaboradores   +10 more
wiley   +1 more source

Efficacy and tolerability of fenfluramine with concomitant potassium bromide in patients with Dravet syndrome

Epilepsia Open, EarlyView.
Abstract Objective To assess the efficacy and tolerability of fenfluramine (FFA) with concomitant potassium bromide (BR) in patients with Dravet syndrome (DS). Methods This multicenter retrospective study, conducted within the German compassionate use program, analyzed BR doses and serum levels before and after FFA initiation, adverse events (AEs ...
Milka Pringsheim, Gerhard Kluger, Adam Strzelczyk, Susanne Schubert‐Bast, Thomas Mayer, Benjamin Glauche, Hiltrud Muhle, Michael Alber, Hartwig Spors, Tilmann Polster, Regina Trollmann, Gerhard Kurlemann, Markus Berndt, Kerstin A. Klotz   +13 more
wiley   +1 more source

Correlation between measured and calculated free phenytoin serum concentration in neurointensive care patients with hypoalbuminemia

Clinical Pharmacology: Advances and Applications, 2018
Seyyede-Sareh Javadi,1 Reza Mahjub,2 Abbas Taher,3 Younes Mohammadi,4 Maryam Mehrpooya1 1Department of Clinical Pharmacy, School of Pharmacy, Hamadan University of Medical Sciences, Hamadan, Iran; 2Department of Pharmaceutics, School of Pharmacy, Hamadan
Javadi SS, Mahjub R, Taher A, Mohammadi Y, Mehrpooya M   +4 more
doaj  

Phenytoin induced dystonia [PDF]

The Turkish Journal of Pediatrics, 2018
The abnormalities of dopaminergic activity in the basal ganglia have been emphasized to be effective in dystonia. We hereby report a case of a 2.5-year-old male patient who presented with tonic-clonic sezures and who developed dystonia after being given phenytoin.
Basar Cander, Hüseyin Çaksen, Birsen Ertekin, Gülsüm Alkan, Mehmet Ergin, Tarık Acar, Sedat Koçak   +6 more
openaire   +3 more sources

Neonatal seizures: Advances in diagnosis and management

Epilepsia Open, EarlyView.
Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz, Ronit M. Pressler, Eli M. Mizrahi   +2 more
wiley   +1 more source

Phenytoin for neuroprotection [PDF]

The Lancet Neurology, 2016
Bernardo Sanchez-Dalmau, Elena H. Martinez-Lapiscina, Pablo Villoslada, Magi Andorra   +3 more
openaire   +7 more sources

Neurotoxicity [PDF]

, 2014
Neurotoxicity refers to the direct or indirect effect of chemicals that disrupt the nervous system of humans or animals. Numerous chemicals can produce neurotoxic diseases in humans, and many more are used as experimental tools to disturb or damage the ...
Brust, Creeley, Feldman, Grandjean, Herken, Panzica, Parent, Pessah, Rice, Román, Spencer, Spencer, Tu, Vinken, Yasui, Zawia   +15 more
core   +2 more sources

Neuronal surface and intracellular antibody testing in patients with long‐term epilepsy

Epilepsia Open, EarlyView.
Abstract Objective We aimed to investigate the frequency of neuronal surface and intracellular antibodies in individuals with long‐term epilepsy and the associated clinical and laboratory characteristics. Methods We tested sera from 223 patients with epilepsy without signs of autoimmune encephalitis and 12 patients with epilepsy and a subacute onset of
Nancy Watanabe, Angelica Lizcano, Tânia K. de Araujo, Renata Barbosa, Marina K. M. Alvim, Andre S. Vieira, Iscia Lopes‐Cendes, Fabio Rogerio, Clarissa L. Yasuda, Fernando Cendes   +9 more
wiley   +1 more source

Comparisons of Four Protein-Binding Models Characterizing the Pharmacokinetics of Unbound Phenytoin in Adult Patients Using Non-Linear Mixed-Effects Modeling

Drugs in R&D, 2020
Background and objective Phenytoin is extensively protein bound with a narrow therapeutic range. The unbound phenytoin is pharmacologically active, but total concentrations are routinely measured in clinical practice.
Heajin Jun, Yan Rong, Catharina Yih, Jordan Ho, Wendy Cheng, Tony K. L. Kiang   +5 more
doaj   +1 more source