Results 1 to 10 of about 10,045 (177)

Phenytoin Toxicity from Cocaine Adulteration [PDF]

open access: yesWestern Journal of Emergency Medicine, 2014
The use of phenytoin (PHT) as a cocaine adulterant was reported decades ago;that practice is still current. Ironically PHT has also been used for the treatment of cocaine dependence.
Carlos J. Roldan
doaj   +6 more sources

Phenytoin Toxicity with High Dose, Concomitant Ascorbic Acid Dosing

open access: yesINNOVATIONS in Pharmacy, 2022
High dose ascorbic acid may increase risk of phenytoin toxicity. This case report demonstrates high phenytoin levels resulting in adverse drug reactions subsequent to dosing concomitantly with high dose vitamin C, or ascorbic acid (AA), as a precaution ...
Michael J. Schuh   +2 more
doaj   +2 more sources

A case of phenytoin toxicity in an adolescent girl mimicking meningoencephalitis and literature review

open access: yesJournal of Integrative Medicine and Research, 2023
The zero-order pharmacokinetics of phenytoin makes it a serious problem in pediatric emergency care since it can cause considerable dose-related toxicity.
Jenith Vijayalakshmi   +4 more
doaj   +1 more source

Acute phenytoin toxicity: An overview

open access: yesAnnals of Indian Psychiatry, 2020
Jamir Pitton Rissardo   +1 more
doaj   +2 more sources

Phenytoin induced Chorea: commonly used antiepileptic drug causing a rare movement disorder [PDF]

open access: yesAsia Pacific Journal of Medical Toxicology, 2020
Background: Phenytoin, a commonly prescribed antiepileptic drug, causes side effects like ataxia, tremor, hirsutism, gum hyperplasia, insomnia, confusion, headache and vertigo when used for longer duration.
Rambhupal NAGIREDDY   +3 more
doaj   +1 more source

Restoration of Germinal Epithelium with Usage of Antioxidant Oils in Phenytoin Induced Testicular Toxicity: A Comparative Study in Rats

open access: yesJournal of Bahria University Medical and Dental College, 2023
Objective: To evaluate antioxidant effect of Virgin Coconut Oil (VCO) and Corn Oil (CO) on germinal thickness (GT) in rats induced with phenytoin toxicity. Study design and setting: An Experimental Longitudinal study was done at AL-Tibri Medical College
Khalique-ur- Rehman   +5 more
doaj   +1 more source

CYP2C9 polymorphisms are associated with phenytoin toxicity in South-Indian epileptic patients

open access: yesJournal of Dr. NTR University of Health Sciences, 2020
Background and Aims: The contribution of CYP2C9 in phenytoin metabolism is generally modest, but it increases with increasing serum phenytoin concentration.
Rakesh Reddy Reddigari   +4 more
doaj   +1 more source

Tacrolimus Induced Organ Failure: Reversal by Activation of the Cytochrome P450-3a System

open access: yesUro, 2021
Tacrolimus is the cornerstone component of all immunosuppressive regimens. Despite its long record of use, very little is known about its acute toxicity syndrome.
Dai D. Nghiem
doaj   +1 more source

Phenytoin-Induced Toxic Epidermal Necrolysis

open access: yesCureus, 2023
Toxic epidermal necrolysis (TEN) is a rare fatal mucocutaneous blistering disorder that can have varied underlying triggers. The percentage of body surface area (BSA) that is impacted by erosive blistering is what separates it from Steven Johnson syndrome (SJS), both of which have the same underlying pathogenesis and are thought to exist on a continuum
Tunuguntla, Mounika Nagarani   +4 more
openaire   +2 more sources

Usual erratic phenomenon, dramatic outcome: a case report of phenytoin toxicity

open access: yesPsychiatry and Clinical Psychopharmacology, 2021
Phenytoin is still one of the most commonly used antiepileptic drugs in clinical practice in many countries. It has a range of usual deleterious and erratic side effects, which have been reported previously including horizontal nystagmus, ataxia and ...
Madhusudan Singh Solanki, Kuldip Kumar
doaj   +1 more source

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