Results 191 to 200 of about 8,172 (201)

Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells

Cell Metabolism, 2018
Charlotte Dubois, Joanna Kalucka, Mark R Sullivan   +2 more
exaly  

Targeting the PHGDH-mTOR Metabolic Axis in Osteosarcoma

2021
openaire   +1 more source

Downregulation of PHGDH expression and hepatic serine level contribute to the development of fatty liver disease

Metabolism: Clinical and Experimental, 2020
Wonseok Lee, Hyungtai Sim, You-Jin Choi
exaly  

Rational Design of Selective Allosteric Inhibitors of PHGDH and Serine Synthesis with Anti-tumor Activity

Cell Chemical Biology, 2017
Qian Wang, Maria V Liberti, Jason W Locasale   +2 more
exaly  

3-Phoshoglycerate Dehydrogenase Deficiency (PHGDH, 1q12)

2008
openaire   +1 more source

A Vinyl Sulfone‐Based Fluorogenic Probe Capable of Selective Labeling of PHGDH in Live Mammalian Cells

Angewandte Chemie - International Edition, 2018
Sijun Pan, Danyang Wang, Jun-Seok Lee
exaly  

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

Nature Chemical Biology, 2016
Michael E Pacold, Kyle R Brimacombe, Sze Ham Chan   +2 more
exaly  

Genome-wide CRISPR/Cas9 library screening identified PHGDH as a critical driver for Sorafenib resistance in HCC

Nature Communications, 2019
Lai Wei, Irene Oi-lin Ng, Carmen Chak-Lui Wong   +2 more
exaly  

Targeting PHGDH reverses the immunosuppressive phenotype of tumor-associated macrophages through α-ketoglutarate and mTORC1 signaling

Cellular and Molecular Immunology
Jayne Louise Wilson, Wolfram Weckwerth, Zhengnan Cai   +2 more
exaly  

Control of PHGDH by NOD2.

openaire   +1 more source