Phosphoglycerate dehydrogenase and Alzheimer’s disease [PDF]
EXCLI Journal : Experimental and Clinical SciencesEXCLI Journal; 24:Doc401; ISSN 1611 ...
Quan-Ying Liu, Shuang-Qing Zhang
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Reduction of stratum corneum ceramides in Neu-Laxova syndrome caused by phosphoglycerate dehydrogenase deficiency [PDF]
Journal of Lipid Research, 2018 Neu-Laxova syndrome (NLS) is a very rare autosomal recessive congenital disorder characterized by disturbed development of the central nervous system and the skin and caused by mutations in any of the three genes involved in de novo l-serine biosynthesis:
Takuya Takeichi +14 more
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Phosphoglycerate Dehydrogenase Overexpression Inhibits Ferroptosis to Repress Calcification of Human Coronary Artery Vascular Smooth Muscle Cells via the P53/SLC7A11 Pathway [PDF]
International Journal of General MedicineYuhai Zou,1,* Dongdong Li,1,* Ge Guan,1 Wenting Liu2 1Department of Cardiology, General Hospital of Southern Theatre Command of PLA, Guangzhou, 510010, People’s Republic of China; 2Department of Otorhinolaryngology, Guangzhou First People’s ...
Zou Y, Li D, Guan G, Liu W
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Novel regulatory mechanism of serine biosynthesis associated with 3-phosphoglycerate dehydrogenase in Arabidopsis thaliana [PDF]
Scientific Reports, 2017 The proteinogenic amino acid l-serine is a precursor for various essential biomolecules in all organisms. 3-Phosphoglycerate dehydrogenase (PGDH) is the first committed enzyme of the phosphorylated pathway of l-serine biosynthesis, and is regulated by ...
Eiji Okamura, Masami Yokota Hirai
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Prognostic value of serum phosphoglycerate dehydrogenase and glycine levels in breast cancer [PDF]
Menopause ReviewHussam Abd Jassem, Anwar Jasib Thaaban
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High Phosphoglycerate Dehydrogenase Expression Induces Stemness and Aggressiveness in Thyroid Cancer [PDF]
Thyroid, 2020 Min Ji Jeon, Mi Hyeon You, Woo Kyung Lee
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Correction: Phosphoglycerate dehydrogenase promotes pancreatic cancer development by interacting with eIF4A1 and eIF4E [PDF]
Journal of Experimental & Clinical Cancer ResearchXuhui Ma +4 more
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The Global mRNA Expression Profiles of Inhibiting PHGDH Induced Cisplatin Resistance in Gastric Cancer [PDF]
Cell Journal, 2022 Objective: Drug resistance is the main hindrance to improve the prognosis of patients with gastric cancer. Aminoacid metabolic reprograming is essential to satisfy the different requirements of cancer cells during drug resistance,of which serine ...
Kailing Pan, Xiaoya Zhao, Wenxia Xu
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Renal UTX-PHGDH-serine axis regulates metabolic disorders in the kidney and liver
Nature Communications, 2022 Chen et al. report on a renal UTX-phosphoglycerate dehydrogenase axis that regulates serine secretion to affect lipid metabolism in the kidney and liver upon over-nutrition, suggesting potential treatment targets for obesity-related diseases.
Hong Chen +15 more
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Nature Communications, 2023 The role of protein arginine methylation in serine metabolism of cancer cells in hepatocellular carcinoma (HCC) remains to be explored. Here, the authors show that phosphoglycerate dehydrogenase (PHGDH) is activated by PRMT1-mediated R236 methylation ...
Kui Wang +13 more
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