Results 31 to 40 of about 23,057 (164)
Memorias do Instituto Oswaldo Cruz, 2015 Trypanosoma evansi, which causes surra, is descended from Trypanosoma brucei brucei, which causes nagana. Although both parasites are presumed to be metabolically similar, insufficient knowledge of T. evansi precludes a full comparison.
S Andrea Moreno, Mayerly Nava
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Neurotransmitters in 3-phosphoglycerate dehydrogenase deficiency
European Journal of Pediatrics, 2000 Item does not contain ...
Koning, T.J. +6 more
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Expanding the clinical spectrum of 3‐phosphoglycerate dehydrogenase deficiency [PDF]
Journal of Inherited Metabolic Disease, 2010 Abstract3‐Phosphoglycerate dehydrogenase (3‐PGDH) deficiency is considered to be a rare cause of congenital microcephaly, infantile onset of intractable seizures and severe psychomotor retardation. Here, we report for the first time a very mild form of genetically confirmed 3‐PGDH deficiency in two siblings with juvenile onset of absence seizures and ...
Tabatabaie, L. +6 more
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mBio, 2022 The ubiquitous presence of toxic arsenate (AsV) in the environment has raised mechanisms of resistance in all living organisms. Generally, bacterial detoxification of AsV relies on its reduction to arsenite (AsIII) by ArsC, followed by the export of ...
Emilio Bueno +7 more
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3‐phosphoglycerate dehydrogenase deficiency in a patient with West syndrome [PDF]
Developmental Medicine & Child Neurology, 2000 3‐phosphoglycerate dehydrogenase deficiency is a severe but treatable disorder of serine synthesis, first described in 1996 (Jaeken et al. 1996a). The patient presented with West syndrome, severe psychomotor delay, failure to thrive, microcephaly, atypical ocular movements, and pyramidal signs.
Pineda M +8 more
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3-PGDH Deficiency, Seizures, and Microcephaly
Pediatric Neurology Briefs, 1998 The beneficial effects of oral L-serine (up to 500 mg/kg/day) and glycine (200 mg/kg/day) in 2 siblings, aged 7 and 5 years, with 3-phosphoglycerate dehydrogenase (3-PGDH) deficiency are reported from University Children’s Hospital, Utrecht, The ...
J Gordon Millichap
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Expressions and roles of key enzymes in serine synthesis pathway in NaAsO2-treated HaCaT cells
环境与职业医学, 2022 BackgroundThe key enzymes of serine synthesis pathway (SSP) play an important role in tumor growth, proliferation, and invasion, but their roles in arsenic carcinogenesis are unclear.ObjectiveTo observe the effects of NaAsO2 treatment on the expressions ...
Fengmin LI +5 more
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The activation of 3‐phosphoglycerate dehydrogenase by L‐methionine [PDF]
FEBS Letters, 1970 Feedback inhibition within the metabolic pathways leading to amino acid biosynthesis is well known in a variety of organisms including higher plants [ 1,2] . Most of the information refers to the effects of amino acids on their own biosynthesis but Jensen [3] has recently pointed out that a regulatory superstructure connecting various metabolic ...
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Phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis [PDF]
Nature Genetics, 2011 Most tumors exhibit increased glucose metabolism to lactate, however, the extent to which glucose-derived metabolic fluxes are used for alternative processes is poorly understood. Using a metabolomics approach with isotope labeling, we found that in some cancer cells a relatively large amount of glycolytic carbon is diverted into serine and glycine ...
Locasale, Jason W. +25 more
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Nature Communications, 2019 Resistance to the tyrosine kinase inhibitor Sorafenib, which is the standard treatment for advanced hepatocellular carcinoma, is a major clinical challenge.
Lai Wei +11 more
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