Results 171 to 180 of about 6,588 (185)

Rational Design of Selective Allosteric Inhibitors of PHGDH and Serine Synthesis with Anti-tumor Activity

Cell Chemical Biology, 2017
Qian Wang, Maria V Liberti, Jason Locasale   +2 more
exaly  

Inhibitors of phosphoglycerate dehydrogenase (PHGDH) and uses thereof

2022
SABATINI DAVID M, PACOLD MICHAEL, BOXER MATTHEW B, ROHDE JASON M, BRIMACOMBE KYLE R, SHEN MIN, BANTUKALLU GANESHA, LIU LI   +7 more
openaire   +1 more source

Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells

Cell Metabolism, 2018
Charlotte Dubois, Peter Carmeliet, Shigeki Furuya   +2 more
exaly  

Insights from Natural Product PHGDH Inhibitor Studies

Journal of Cellular Signaling, 2022
openaire   +1 more source

3-Phoshoglycerate Dehydrogenase Deficiency (PHGDH, 1q12)

2008
openaire   +1 more source

Targeting PHGDH reverses the immunosuppressive phenotype of tumor-associated macrophages through α-ketoglutarate and mTORC1 signaling

Cellular and Molecular Immunology
Zhengnan Cai, Petra Heffeter, Elke H. Heiß   +2 more
exaly  

A Vinyl Sulfone-Based Fluorogenic Probe Capable of Selective Labeling of PHGDH in Live Mammalian Cells

Angewandte Chemie - International Edition, 2018
Jun-Seok Lee, Sijun Pan, Shao Q Yao
exaly  

Control of PHGDH by NOD2.

openaire   +1 more source

PHGDH: a metabolic switch in tumor drug resistance and a therapeutic target

Drug Discovery Today
Song-Song Shi, Si-Yi Chen, Wen Zhang, Guo-Wu Rao, Quan Zheng   +4 more
openaire   +2 more sources

THIENOPYRIMIDYLAMINE DERIVATIVES AS PHGDH INHIBITORS

PALA DANIELE, GUARIENTO SARA, BRUNO PAOLO, KARAWAJCZYK ANNA, ŁUKASIEWICZ MICHAŁ, WOŁEK BARBARA KAROLINA, FRĄCZEK TOMASZ KRZYSZTOF   +6 more
openaire   +1 more source