Results 151 to 160 of about 5,503 (166)

Targeting the PHGDH-mTOR Metabolic Axis in Osteosarcoma

2021
openaire   +1 more source

The NMDA receptor activation by d -serine and glycine is controlled by an astrocytic Phgdh-dependent serine shuttle

Proceedings of the National Academy of Sciences of the United States of America, 2019
Herman Wolosker, Simone Engelender, Marialaura Marchetti   +2 more
exaly  

Inhibitors of phosphoglycerate dehydrogenase (PHGDH) and uses thereof

2022
SABATINI DAVID M, PACOLD MICHAEL, BOXER MATTHEW B, ROHDE JASON M, BRIMACOMBE KYLE R, SHEN MIN, BANTUKALLU GANESHA, LIU LI   +7 more
openaire   +1 more source

High level PHGDH expression in breast is predominantly associated with keratin 5‐positive cell lineage independently of malignancy

Molecular Oncology, 2015
David Rimm, JOSÉ Moreira, Gromova Irina   +2 more
exaly  

Deletion of PHGDH in adipocytes improves glucose intolerance in diet-induced obese mice

Biochemical and Biophysical Research Communications, 2018
, Isao Usui, Yoshio Hirabayashi
exaly  

PHGDH: a metabolic switch in tumor drug resistance and a therapeutic target

Drug Discovery Today
Song-Song Shi, Si-Yi Chen, Wen Zhang, Guo-Wu Rao, Quan Zheng   +4 more
openaire   +2 more sources

Control of PHGDH by NOD2.

openaire   +1 more source

Targeting PHGDH reverses the immunosuppressive phenotype of tumor-associated macrophages through α-ketoglutarate and mTORC1 signaling

Cellular and Molecular Immunology
Zhengnan Cai, Petra Heffeter, Sonja Hager   +2 more
exaly  

3-Phoshoglycerate Dehydrogenase Deficiency (PHGDH, 1q12)

2008
openaire   +1 more source

PHGDH knockdown increases sensitivity to SR1, an aryl hydrocarbon receptor antagonist, in colorectal cancer by activating the autophagy pathway

FEBS Journal
Hong-Sheng Zhang
exaly