Results 111 to 120 of about 3,130,255 (294)

Applying Hubbert Curves and Linearization to Rock Phosphate [PDF]

open access: yes
Rock phosphate is a critical, nonrenewable resource for which there is no known substitute in agriculture. Cordell, Drangert, and White (2009) use Hubbert methodology (1956) to estimate the peak--the year after which production will monotonically decline-
Cullen S. Hendrix
core  

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Optical band gap and ir spectra of glasses in the system [Nd2O3](r)-[CuO](35-x)-[P2O5](65) [PDF]

open access: yes, 2006
The infra red and ultraviolet-visible spectroscopiy of neodymium copper phosphate glasses on the [Nd2O3](x)-[CuO](35-x)-[P2O5](65) system with ...
Budi, Agus Setyo, Sahar, Md. Rahim
core  

Serum phosphate and social deprivation independently predict all-cause mortality in chronic kidney disease [PDF]

open access: yes, 2015
Background: Hyperphosphataemia is linked to cardiovascular disease and mortality in chronic kidney disease (CKD). Outcome in CKD is also affected by socioeconomic status. The objective of this study was to assess the associations between serum phosphate,
Findlay, Mark D.   +8 more
core   +2 more sources

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Monovalent counterion distributions at highly charged water interfaces: Proton-transfer and Poisson-Boltzmann theory

open access: yes, 2005
Surface sensitive synchrotron-X-ray scattering studies reveal the distributions of monovalent ions next to highly charged interfaces. A lipid phosphate (dihexadecyl hydrogen-phosphate) was spread as a monolayer at the air-water interface, containing CsI ...
A. G. Moreira   +10 more
core   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Analysis of Human Kidney Stones Using Advanced Characterization Techniques

open access: yesCrystals
A comprehensive analysis of kidney stones is essential for the future treatment of patients. Almost all of the methods available for kidney stone analysis were used in this study.
Jelena Brdarić Kosanović   +7 more
doaj   +1 more source

Fire retardancy of bis[2-(methacryloyloxy)ethyl] phosphate modified poly(methyl methacrylate) nanocomposites containing layered double hydroxide and montmorillonite [PDF]

open access: yes, 2009
Copolymer nanocomposites were prepared by suspension copolymerization of bis[2-(methacryloyloxy)ethyl] phosphate and methyl methacrylate, together with bis(2-ethylhexyl) phosphate layered double hydroxide and a montmorillonite, Cloisite 93A.
Chen, Dan   +3 more
core   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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