(Pro)renin Receptor Regulates Phosphate Homeostasis in Rats via Releasing Fibroblast Growth Factor-23 [PDF]
Frontiers in Physiology, 2022 Phosphate (Pi) is one of the basic necessities required for sustenance of life and its metabolism largely relies on excretory function of the kidney, a process chiefly under the endocrine control of bone-derived fibroblast growth factor 23 (FGF23 ...
Aihua Lu +7 more
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Multifaceted role of autophagy in regulating phosphate homeostasis and developmental root plasticity [PDF]
Autophagy Reports, 2023 Macroautophagy/autophagy delivers cytoplasmic constituents to the lysosome/vacuole for degradation and recycling, wherein regulates diverse aspects of cellular homeostasis.
Tzu-Yin Liu +3 more
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Genetic Engineering of the Biosynthesis of Glycine Betaine Modulates Phosphate Homeostasis by Regulating Phosphate Acquisition in Tomato [PDF]
Frontiers in Plant Science, 2019 Glycine betaine (GB), as a putative compatible substance, protects plants against the damaging effects of abiotic stresses. Phosphorus deficiency is one type of abiotic stress that is detrimental to plant growth. Maintenance of phosphate (Pi) homeostasis
Daxing Li +6 more
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Kidney glycolysis serves as a mammalian phosphate sensor that maintains phosphate homeostasis [PDF]
The Journal of Clinical Investigation, 2023 How phosphate levels are detected in mammals is unknown. The bone-derived hormone fibroblast growth factor 23 (FGF23) lowers blood phosphate levels by reducing kidney phosphate reabsorption and 1,25(OH)2D production, but phosphate does not directly ...
Wen Zhou +14 more
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LPCAT1 controls phosphate homeostasis in a zinc-dependent manner
eLife, 2018 All living organisms require a variety of essential elements for their basic biological functions. While the homeostasis of nutrients is highly intertwined, the molecular and genetic mechanisms of these dependencies remain poorly understood.
Mushtak Kisko +10 more
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Downregulation of GeBP-like α factor by MiR827 suggests their involvement in senescence and phosphate homeostasis [PDF]
BMC Biology, 2021 Background Leaf senescence is a genetically controlled degenerative process intimately linked to phosphate homeostasis during plant development and responses to environmental conditions.
Chao Ma +3 more
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Age-dependent sex differences in calcium and phosphate homeostasis [PDF]
Endocrine Connections, 2021 Background: Sex differences in calcium and phosphate have been observed. We aimed to assess a relation with age. Methods: We used the laboratory values of serum calcium, phosphate and albumin from three different samples ( 2005, 2010 and 2014 years ...
W N H Koek +7 more
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Two bifunctional inositol pyrophosphate kinases/phosphatases control plant phosphate homeostasis [PDF]
eLife, 2019 Many eukaryotic proteins regulating phosphate (Pi) homeostasis contain SPX domains that are receptors for inositol pyrophosphates (PP-InsP), suggesting that PP-InsPs may regulate Pi homeostasis.
Jinsheng Zhu +14 more
doaj +2 more sources
A tRNA modification balances carbon and nitrogen metabolism by regulating phosphate homeostasis [PDF]
eLife, 2019 Cells must appropriately sense and integrate multiple metabolic resources to commit to proliferation. Here, we report that S. cerevisiae cells regulate carbon and nitrogen metabolic homeostasis through tRNA U34-thiolation. Despite amino acid sufficiency,
Ritu Gupta +5 more
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Effects of empagliflozin on markers of calcium and phosphate homeostasis in patients with type 2 diabetes – Data from a randomized, placebo-controlled study [PDF]
Bone Reports, 2022 Background and aim: Sodium-glucose cotransporter-2 (SGLT2) inhibitors, glucose-lowering drugs that increase urinary glucose excretion have been shown to reduce CV events in patients with type 2 diabetes (T2D).
Matthias Rau +7 more
doaj +2 more sources