Results 11 to 20 of about 823,820 (320)

Alpha Klotho and phosphate homeostasis [PDF]

open access: bronzeJournal of Endocrinological Investigation, 2014
The Klotho family consists of three single-pass transmembrane proteins—αKlotho, βKlotho and γKlotho. Each of them combines with fibroblast growth factor (FGF) receptors (FGFRs) to form receptor complexes for various FGF’s. αKlotho is a co-receptor for physiological FGF23 signaling and appears essential for FGF23-mediated regulation of mineral ...
Aihua Bian, Changying Xing, Meng-Ming Hu
openalex   +4 more sources

HvPHR1 as a key gene in maintaining phosphate homeostasis in barley

open access: goldPlant Stress
Phosphorus is an essential macronutrient for all living organisms. Although it is abundant in the Earth’s crust, inorganic phosphate (Pi)—accessible to plants—is often limited due to the soil’s physicochemical properties. To cope with Pi scarcity, plants
Wenhao Yue   +7 more
doaj   +2 more sources

A small signaling domain controls PPIP5K phosphatase activity in phosphate homeostasis. [PDF]

open access: goldNat Commun
Raia P   +9 more
europepmc   +4 more sources

Interactions of sclerostin with FGF23, soluble klotho and vitamin D in renal transplantation [PDF]

open access: yes, 2017
Relationships of Sclerostin, a bone anti-anabolic protein, with biomarkers of mineral bone disorders in chronic kidney disease are still unsettled, in particular in kidney transplant (KTR).
Farcomeni, Alessio   +7 more
core   +12 more sources

A Role for Inositol Pyrophosphates in the Metabolic Adaptations to Low Phosphate in Arabidopsis

open access: yesMetabolites, 2021
Phosphate is a major plant macronutrient and low phosphate availability severely limits global crop productivity. In Arabidopsis, a key regulator of the transcriptional response to low phosphate, phosphate starvation response 1 (PHR1), is modulated by a ...
Eric S. Land   +7 more
doaj   +1 more source

Phosphate homeostasis and disorders [PDF]

open access: yesAnnals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2014
Recent studies of inherited disorders of phosphate metabolism have shed new light on the understanding of phosphate metabolism. Phosphate has important functions in the body and several mechanisms have evolved to regulate phosphate balance including vitamin D, parathyroid hormone and phosphatonins such as fibroblast growth factor-23 (FGF23). Disorders
P, Manghat, R, Sodi, R, Swaminathan
openaire   +2 more sources

Dysregulating PHO Signaling via the CDK Machinery Differentially Impacts Energy Metabolism, Calcineurin Signaling, and Virulence in Cryptococcus neoformans

open access: yesmBio, 2023
Fungal pathogens uniquely regulate phosphate homeostasis via the cyclin-dependent kinase (CDK) signaling machinery of the phosphate acquisition (PHO) pathway (Pho85 kinase-Pho80 cyclin-CDK inhibitor Pho81), providing drug-targeting opportunities.
Bethany Grace Bowring   +10 more
doaj   +1 more source

The PPIP5K Family Member Asp1 Controls Inorganic Polyphosphate Metabolism in S. pombe

open access: yesJournal of Fungi, 2021
Inorganic polyphosphate (polyP) which is ubiquitously present in both prokaryotic and eukaryotic cells, consists of up to hundreds of orthophosphate residues linked by phosphoanhydride bonds.
Marina Pascual-Ortiz   +3 more
doaj   +1 more source

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