Alpha Klotho and phosphate homeostasis [PDF]
The Klotho family consists of three single-pass transmembrane proteins—αKlotho, βKlotho and γKlotho. Each of them combines with fibroblast growth factor (FGF) receptors (FGFRs) to form receptor complexes for various FGF’s. αKlotho is a co-receptor for physiological FGF23 signaling and appears essential for FGF23-mediated regulation of mineral ...
Aihua Bian, Changying Xing, Meng-Ming Hu
openalex +4 more sources
Genome-Wide Analyses of Phosphate Transporters in Wild Rice (<i>Oryza brachyantha</i>) Revealed Their Evolution and Regulatory Roles in Phosphate Homeostasis. [PDF]
Zhao X, Yung WS, Fan K, Chen S, Lam HM.
europepmc +3 more sources
HvPHR1 as a key gene in maintaining phosphate homeostasis in barley
Phosphorus is an essential macronutrient for all living organisms. Although it is abundant in the Earth’s crust, inorganic phosphate (Pi)—accessible to plants—is often limited due to the soil’s physicochemical properties. To cope with Pi scarcity, plants
Wenhao Yue +7 more
doaj +2 more sources
A small signaling domain controls PPIP5K phosphatase activity in phosphate homeostasis. [PDF]
Raia P +9 more
europepmc +4 more sources
Interactions of sclerostin with FGF23, soluble klotho and vitamin D in renal transplantation [PDF]
Relationships of Sclerostin, a bone anti-anabolic protein, with biomarkers of mineral bone disorders in chronic kidney disease are still unsettled, in particular in kidney transplant (KTR).
Farcomeni, Alessio +7 more
core +12 more sources
A Role for Inositol Pyrophosphates in the Metabolic Adaptations to Low Phosphate in Arabidopsis
Phosphate is a major plant macronutrient and low phosphate availability severely limits global crop productivity. In Arabidopsis, a key regulator of the transcriptional response to low phosphate, phosphate starvation response 1 (PHR1), is modulated by a ...
Eric S. Land +7 more
doaj +1 more source
The MYB-CC Transcription Factor PHOSPHATE STARVATION RESPONSE-LIKE 7 (PHL7) Functions in Phosphate Homeostasis and Affects Salt Stress Tolerance in Rice. [PDF]
Yang WT +8 more
europepmc +3 more sources
Phosphate homeostasis and disorders [PDF]
Recent studies of inherited disorders of phosphate metabolism have shed new light on the understanding of phosphate metabolism. Phosphate has important functions in the body and several mechanisms have evolved to regulate phosphate balance including vitamin D, parathyroid hormone and phosphatonins such as fibroblast growth factor-23 (FGF23). Disorders
P, Manghat, R, Sodi, R, Swaminathan
openaire +2 more sources
Fungal pathogens uniquely regulate phosphate homeostasis via the cyclin-dependent kinase (CDK) signaling machinery of the phosphate acquisition (PHO) pathway (Pho85 kinase-Pho80 cyclin-CDK inhibitor Pho81), providing drug-targeting opportunities.
Bethany Grace Bowring +10 more
doaj +1 more source
The PPIP5K Family Member Asp1 Controls Inorganic Polyphosphate Metabolism in S. pombe
Inorganic polyphosphate (polyP) which is ubiquitously present in both prokaryotic and eukaryotic cells, consists of up to hundreds of orthophosphate residues linked by phosphoanhydride bonds.
Marina Pascual-Ortiz +3 more
doaj +1 more source

