Results 51 to 60 of about 5,041,800 (310)

Interaction and Regulation Between Lipid Mediator Phosphatidic Acid and Circadian Clock Regulators

open access: yesThe Plant Cell, 2019
The lipid mediator phosphatidic acid interacts with and modulates the function of the core clock regulators and may act as a cellular conduit to integrate the circadian clock with lipid metabolism.
Sang-Chul Kim   +4 more
semanticscholar   +1 more source

The antimicrobial activity of exogeno us anionic phospholipids against Mycobacterium tuberculosis and Escherichia coli

open access: yesТонкие химические технологии, 2016
The effect of anionic phospholipids, namely, cardiolipin, phosphatidylglycerol and phosphatidic acid, on the growth of gram-negative bacteria E. coli BL21(DE3), as well as gram-positive bacteria M. tuberculosis H37Rv was investigated in this study.
Yu. L. Mikulovich   +3 more
doaj   +1 more source

Analysis of naturally occurring mutations in the human lipodystrophy protein seipin reveals multiple potential pathogenic mechanisms [PDF]

open access: yes, 2013
Peer reviewedPublisher ...
Dennis, Rowena J   +5 more
core   +2 more sources

Phosphoprotein enriched in astrocytes (PEA)-15 : A potential therapeutic target in multiple disease states [PDF]

open access: yes, 2014
Copyright © 2014 Elsevier Inc.
Greig, Fiona H, Nixon, Graeme F
core   +1 more source

Regulation of Membrane Turnover by Phosphatidic Acid: Cellular Functions and Disease Implications

open access: yesFront. Cell Dev. Biol., 2019
Phosphatidic acid (PA) is a simple glycerophospholipid with a well-established role as an intermediate in phospholipid biosynthesis. In addition to its role in lipid biosynthesis, PA has been proposed to act as a signaling molecule that modulates several
Rajan Thakur   +3 more
semanticscholar   +1 more source

Tailoring a Functional Synthetic Microbial Community Alleviates Fusobacterium nucleatum‐infected Colorectal Cancer via Ecological Control

open access: yesAdvanced Science, EarlyView.
The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou   +11 more
wiley   +1 more source

Red Blood Cell Membrane Lipidomics: Potential Biomarkers Detecting Method for Plasma Volume Overload and Major Adverse Cardiovascular Events in Chronic Heart Failure Patients

open access: yesAdvanced Science, EarlyView.
A novel RBC indicator, ESI, is better than the traditional RBC indicators and is associated with CHF prevalence and in‐hospital death. RBC membrane lipidomics, Cer 18:0;O2/16:0, and LPE 18:0, are associated with plasma volume overload and MACE in CHF patients, but these plasma lipids could not.
Lin Zhang   +12 more
wiley   +1 more source

Phosphatidic acid increases Notch signalling by affecting Sanpodo trafficking during Drosophila sensory organ development

open access: yesScientific Reports, 2020
Organ cell diversity depends on binary cell-fate decisions mediated by the Notch signalling pathway during development and tissue homeostasis. A clear example is the series of binary cell-fate decisions that take place during asymmetric cell divisions ...
Ignacio Medina-Yáñez   +4 more
doaj   +1 more source

Identification of Key Phospholipids That Bind and Activate Atypical PKCs

open access: yesBiomedicines, 2021
PKCζ and PKCι/λ form the atypical protein kinase C subgroup, characterised by a lack of regulation by calcium and the neutral lipid diacylglycerol. To better understand the regulation of these kinases, we systematically explored their interactions with ...
Suresh Velnati   +10 more
doaj   +1 more source

The triumvirate of signaling molecules controlling Toxoplasma microneme exocytosis: Cyclic GMP, calcium, and phosphatidic acid

open access: yesPLoS Pathogens, 2019
To elicit effective invasion and egress from infected cells, obligate intracellular parasites of the phylum Apicomplexa rely on the timely and spatially controlled exocytosis of specialized secretory organelles termed the micronemes.
H. Bullen   +2 more
semanticscholar   +1 more source

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