Results 101 to 110 of about 155,795 (339)

A mechanism for suppression of the CDP-choline pathway during apoptosis

open access: yesJournal of Lipid Research, 2013
Inhibition of the CDP-choline pathway during apoptosis restricts the availability of phosphatidylcholine (PtdCho) for assembly of membranes and synthesis of signaling factors.
Craig C. Morton   +3 more
doaj   +1 more source

Effect of Bilayer Thickness on Membrane Bending Rigidity

open access: yes, 2004
The bending rigidity $k_c$ of bilayer vesicles self-assembled from amphiphilic diblock copolymers has been measured using single and dual-micropipet techniques.
Bermudez, H.   +2 more
core   +1 more source

Strategic Design of Aptamer‐Guided Aggregation‐Induced Emission Nanoparticles for Targeted Photodynamic Therapy in Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study presents MF3Ec‐TBPP nanoparticles for targeted photodynamic therapy of Luminal A breast cancer. These nanoparticles combine an AIE‐based photosensitizer with an aptamer. Tests show they effectively inhibit tumor growth while protecting healthy tissue via aggregation and dipalmitoylphosphatidylcholine, indicating potential for improved ...
Charlie C. H. Ma   +13 more
wiley   +1 more source

Study of the transfer of phospholipids from the endoplasmic reticulum to the outer and inner mitochondrial membranes

open access: yesJournal of Lipid Research, 1971
Isolated mitochondria cannot synthesize their own phospholipids, there is only an exchange between exogenous and mitochondrial phospholipid fatty acids.
MARIE-THÉRÈSE SAUNER, MARIANNE LÉVY
doaj   +1 more source

Elucidating mysteries of phase-segregated membranes: Mobile-lipid recruitment facilitates pores' passage to the fluid phase [PDF]

open access: yes, 2018
Phase segregation of multicomponent lipid bilayers leads to, under phase-coexistence conditions, domain formation, featuring delimitation by essentially one-dimensional borders.
del Popolo, Mario Gabriel   +2 more
core   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

open access: yesAdvanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi   +10 more
wiley   +1 more source

Engineering Neutrophil Vesicles for Synergistic Protection against Ischemia/Reperfusion Injury after Lung Transplant

open access: yesAdvanced Science, EarlyView.
Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan   +10 more
wiley   +1 more source

Analysis of triacylglycerol and phospholipid sn‐positional isomers by liquid chromatographic and mass spectrometric methodologies

open access: yesMass Spectrometry Reviews, EarlyView., 2023
Abstract Analysis of triacylglycerol (TG) and phospholipid sn‐positional isomers can be divided into two main categories: (a) direct separation by chromatography or other means such as ion mobility mass spectrometry and (b) quantification of regioisomer ratios by structurally informative fragment ions with mass spectrometric methods.
Mikael Fabritius, Baoru Yang
wiley   +1 more source

Soy Protein Isolate-Phosphatidylcholine Nanoemulsions Prepared Using High-Pressure Homogenization

open access: yesNanomaterials, 2018
The nanoemulsions of soy protein isolate-phosphatidylcholine (SPI-PC) with different emulsion conditions were studied. Homogenization pressure and homogenization cycle times were varied, along with SPI and PC concentration. Evaluations included turbidity,
Yang Li   +9 more
doaj   +1 more source

Regulating PPARG Reduces Lipid Accumulation in Microglia and Promotes Functional Recovery After Spinal Cord Injury

open access: yesAdvanced Science, EarlyView.
Macrophages infiltrate the spinal cord post‐injury, decreasing over time. Microglia phagocytose myelin debris, increasing lipid accumulation. Macrophage deletion improves outcomes, while microglial deletion worsens them. The LD+ microglia subtype shows abnormal Pparg signaling.
Mingran Luo   +17 more
wiley   +1 more source

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