Results 101 to 110 of about 82,361 (247)

Advancing design strategies in smart stimulus‐responsive liposomes for drug release and nanomedicine

BMEMat, EarlyView.
Schematic illustration of stimulus‐responsive liposomes designed for controlled drug release and nanomedicine. The innermost circle represents different liposomal structures, including unilamellar, multilamellar, and multivesicular liposomes. The middle layer illustrates the responsive phospholipid components.
Yuchen Guo, Nan Li, Daiwei Zhang, Jingya Gu, Zhihuan Liao, Zihao Teng, Xiangfu Du, Peter S. Timashev, Shipeng Chen, Shuaidong Huo   +9 more
wiley   +1 more source

Dietary phospholipid carriers of DHA do not increase brain DHA levels: a replication study

Journal of Lipid Research
DHA is primarily found in fish and seafood as triacylglycerols and phospholipids (PLs). Oral administration of PL DHA forms, sn-1 lysophosphatidylcholine-DHA (sn-1 LPC-DHA) and di-DHA phosphatidylcholine (di-DHA-PC), has been suggested to increase brain ...
Brinley J. Klievik, Yan Fu, Aidan D. Tyrrell, Chuck T. Chen, Adam H. Metherel, Richard P. Bazinet   +5 more
doaj   +1 more source

Phosphatidylcholine

Biophysical Journal, 1992
Thewalt, Jenifer L., Bloom, Myer
openaire   +1 more source

Untargeted Metabolomics Identifies N‐Lactoyl‐Amino Acids as Dose‐Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes

Clinical Pharmacology &Therapeutics, EarlyView.
Metformin is the most widely prescribed antidiabetic drug, yet adherence remains difficult to objectively assess. Using untargeted metabolomics and lipidomics, we analyzed plasma from 637 patients with type 2 diabetes (T2D) with confirmed metformin use and 143 nondiabetic controls, annotating 614 metabolites.
Tomas Cajka, Jiri Hricko, Lucie Rudl Kulhava, Michaela Paucova, Michaela Novakova, Veronika Hola, Stanislava Rakusanova, Oliver Fiehn, Vojtech Skop, Ivana Lankova, Iva Miskova, Terezie Pelikanova, Martin Haluzik   +12 more
wiley   +1 more source

Increasing phospholipid biomimicry governs water permeability in droplet interface bilayers

Droplet, EarlyView.
Increasing phospholipid biomimicry in droplet interface bilayers alters how membranes respond to “membrane‐active molecules” such as cholesterol and niacin. This shows that membranes made using synthetic lipids can overestimate small‐molecule effects, highlighting the importance of using biomimetic lipid compositions to improve physiological relevance ...
Alejandro Forigua, Katherine S. Elvira
wiley   +1 more source

Isomer Composition Assessment of Synthetic Phosphatidylethanol by Collision‐Induced and Ozone‐Induced Dissociation Mass Spectrometry

Drug Testing and Analysis, EarlyView.
This study examines the isomeric composition of PEth reference materials and compares it with the natural variation in isomer distribution found in blood samples. ABSTRACT The direct blood‐alcohol biomarker phosphatidylethanol (PEth), especially its most abundant analogue 1‐palmitoyl‐2‐oleoyl‐sn‐phosphatidylethanol (PEth 16:0/18:1) has gained ...
Matthias Bantle, Jackson O. T. Long, Samuel C. Brydon, Reuben S. E. Young, Stephen J. Blanksby, Wolfgang Weinmann, Marc Luginbühl   +6 more
wiley   +1 more source

Pss knockdown in the midgut causes growth retardation in Drosophila similar to that in human LMHD

Developmental Dynamics, EarlyView.
Abstract Background Phosphatidylserine synthase (PSS), localized in the mitochondrial membrane, synthesizes phosphatidylserine. In humans, mutations in Pss lead to Lenz–Majewski hyperostotic dwarfism, a disorder affecting growth and development. The effects of Pss mutations on the growth of Drosophila melanogaster are not fully known. Hence, this study
Kwan‐Young Kim, You‐Lim Hwang, Sunwoo Yeom, Seung‐Hae Kwon, Sang‐Hak Jeon   +4 more
wiley   +1 more source

Development and in vitro evaluation of chitosan nanoparticles encapsulating Phoenix dactylifera L. (Ajwah) seed extract with supporting in silico molecular docking analysis

Food Biomacromolecules, EarlyView.
Abstract This research describes the engineering of chitosan nanoparticles (CS NPs) via ionic gelation to encapsulate Ajwah seed extract (ASE), repurposing a plant waste product for its documented antioxidant and anticancer potential. Physicochemical analysis confirmed the formation of stable nanoparticles with hydrodynamic diameters between 152.3 and ...
Jailan E. Elhalawani, Amro Shetta, Wael Mamdouh   +2 more
wiley   +1 more source

Micro and Nanoencapsulation of Omega‐3 Fatty Acids: Functional Applications and Future Perspectives in Food Systems

Food Safety and Health, EarlyView.
Whey protein‐based microencapsulation for omega‐3 PUFA delivery in food systems. Objective: Enhance oxidative stability & bioavailability of omega‐3 PUFAs using whey protein as an encapsulating agent. Current methods: Spray drying & coacervation—effective but limited by heat sensitivity and encapsulation efficiency. Emerging technologies: Electrospray &
Jihan M. Kassem, Fadwa W. Abdulqahar, Ahmed A. Zaky, Mohamed Said Boulkrane, Aya Darwish, Amr Farouk, Beraat Ozçelik, Osama Magouz, Xueming Liu, Tamer M. El‐Messery   +9 more
wiley   +1 more source

Krill Oil-Incorporated Liposomes As An Effective Nanovehicle To Ameliorate The Inflammatory Responses Of DSS-Induced Colitis

International Journal of Nanomedicine, 2019
Jin-Hee Kim,1,* Soon-Seok Hong,1,* Myoungsoo Lee,2 Eun-Hye Lee,1 Inmoo Rhee,1 Sun-Young Chang,2 Soo-Jeong Lim1 1Department of Integrated Bioscience and Biotechnology, Sejong University, Seoul 05006, Republic of Korea; 2Laboratory of Microbiology, College
Kim JH, Hong SS, Lee M, Lee EH, Rhee I, Chang SY, Lim SJ   +6 more
doaj