Results 161 to 170 of about 149,942 (303)

Role of TRAIL in mediating the effect of lipidome on breast cancer: a Mendelian randomization study. [PDF]

Transl Cancer Res
Wang X, Yang T, Wang X, Hu K, Hu J, Shi H, Jing J, Luo T.   +7 more
europepmc   +1 more source

Boron‐10 carriers and their applications in boron neutron capture therapy

Precision Radiation Oncology, EarlyView.
Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang, Mengqi Shi, Zhichen Mao, Weiya Chen, Xiaoling Li, Xiao Yan Zhao, Zhigang Liu, Xiao Xu   +7 more
wiley   +1 more source

Role of abnormal phosphatidylcholine metabolism in endoplasmic reticulum stress-induced carotid artery plaque destabilization. [PDF]

Atheroscler Plus
Hu Q, Zhang H, Wang X, Huang J, Jiang X, Li M, Chen D.   +6 more
europepmc   +1 more source

x‐Ray Structure of Streptomyces avermitilis Phospholipase D Reveals a Ca2+‐Stabilized Expanded Active‐Site Cleft Adapted for Phospholipid Binding

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT Phospholipase D (PLD) catalyzes the hydrolysis of phospholipids to generate phosphatidic acid and free head groups such as choline. Among bacterial PLD enzymes, Streptomyces chromofuscus PLD (SchPLD), a member of the alkaline phosphatase D (PhoD) superfamily, exhibits unique Ca2+‐dependent phospholipase activity.
Yoshiaki Yasutake, Tatsuya Hirata, Shunsuke Nomura, Kenji Konishi, Kazunari Yoneda, Shin‐ichi Sakasegawa, Haruhiko Sakuraba   +6 more
wiley   +1 more source

Plasma metabolomic profiles and risk of hip fracture among US individuals: a nested case-control and prospective cohort study. [PDF]

EBioMedicine
Wu Z, Sun Q, Liu B, Curhan G, Avila-Pacheco J, Clish C, Zeleznik OA, Paik JM.   +7 more
europepmc   +1 more source

Cross‐Linking Mass Spectrometry of the Antimicrobial Peptides Magainin 2 and PGLa Reveals Heterodimerization in Micellar Medium

Rapid Communications in Mass Spectrometry, EarlyView.
ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler, Elise Glattard, Nicolas Arnaud, Johana Chicher, Philippe Hammann, Emmanuelle Leize‐Wagner, Burkhard Bechinger, Noelle Potier   +7 more
wiley   +1 more source

Aging-associated decline of phosphatidylcholine synthesis is a malleable trigger of natural mitochondrial aging. [PDF]

Nat Commun
Poliezhaieva T, Li Y, Chaudhari PS, Isildak U, Alonso-Pernas P, Valentim IS, Su F, Espada L, Bayar M, Fu L, Koeberle A, Dönertaş HM, Ermolaeva MA.   +12 more
europepmc   +1 more source

PFOA Exposure Elicits Quantitative Lipidomic Changes in the Pancreas in a Mouse Model of Pancreatic Cancer

Environmental Toxicology, EarlyView.
ABSTRACT Pancreatic cancer is the fourth leading cause of cancer deaths in the US and predicted to rise to second by 2030. Several risk factors have been identified as potential contributors to pancreatic cancer development including lifestyle factors and long‐term exposure to occupational and environmental carcinogens.
Barbara A. Hocevar, Lisa M. Kamendulis
wiley   +1 more source

Association between egg-derived phosphatidylcholine intake and trimethylamine N-oxide in healthy middle-aged and older adults. [PDF]

Lipids Health Dis
Wang W, Takeda Y, Kimura M, Matsuoka R, Hashimoto T, Yanaka N, Sugano M.   +6 more
europepmc   +1 more source

Role of phospholipase A2 in the stimulation of sponge cell proliferation by homologous lectin. [PDF]

, 1989
Friese, K., Fritsche, U., Gramzow, M., Kreuter, M., Kurelec, B., Müller, W., Robitzki, A., Schröder, H., Zimmermann, H.   +8 more
core   +1 more source