Mendelian randomization of plasma lipidome and temporomandibular joint disorders. [PDF]
Jiang Y, Yuan H, Cao Y.
europepmc +1 more source
ABSTRACT Rationale In this study, we applied cross‐linking mass spectrometry (XL‐MS) to characterize the oligomeric states of a PGLa/magainin 2 mixture and gain insight into the heterodimerization previously suggested in the literature. Both peptides have shown a synergistic enhancement of activity when tested in antimicrobial assays; however, the ...
Emilie Hirschler +7 more
wiley +1 more source
Phosphatidylcholine — Mg2+ equilibria in a monolayer at the air/water interface
Petelska Aneta, Figaszewski Zbigniew
doaj +1 more source
Peptide‐based antibacterial nanoplatforms, encompassing self‐assembled peptides and peptide‐engineered inorganic, polymeric, and lipid nanocarriers, are systematically reviewed. The article highlights design principles and stimuli‐responsive regulation for improving peptide stability, delivery efficiency, and antibacterial performance.
Peng Tan +8 more
wiley +1 more source
Multi-omics Mendelian randomization and experimental validation identify PRKAB1 as a regulator of phosphatidylcholine metabolism in IBD. [PDF]
Wu S, Yi J, Chen X, Peng L.
europepmc +1 more source
This study presents a microfluidic fabrication method for millimeter‐scale multicore hydrogel capsules containing multiple aqueous cores physically isolated by oil layers. These macrocapsules exhibit mechanical and chemical robustness effectively protecting cargos under simulated gastric conditions.
Hye‐Seon Jeong +4 more
wiley +1 more source
Oxidomics of Human Plasma Reveals Lower Oxidized Lipids After Acute Intake of Polyphenol-Enriched Flaxseed Oil: A Randomized Crossover Exercise Trial. [PDF]
Aurum FS +5 more
europepmc +1 more source
Reverse Micelles: The Gateway for Oral (Poly)Peptide Delivery
RM achieve superior oral peptide delivery through high loading capacity, strong lipophilicity, and a low‐hydration microenvironment that protects against enzymatic degradation. Meanwhile, dRM provides favorable permeation‐enhancing interactions and a consistent safety profile, collectively driving enhanced oral performance.
Marlene Ramona Schmidt +2 more
wiley +1 more source
Formulation-dependent colloidal properties of redispersible lycopene nanoparticles: storage stability and enhanced <i>in vitro</i> bioactivity. [PDF]
Oanh HT +5 more
europepmc +1 more source
Conquering the stronghold: Membrane‐targeting anti‐infective drug discovery
This perspective elucidates how XM‐01 and BLA combat infections through modulating pathogen membranes, disrupting biological processes, and potentiating therapeutics, offering cutting‐edge insights into anti‐infective drug mechanisms, innovations, and clinical translation.
Yanxu Hou +4 more
wiley +1 more source

