Results 1 to 10 of about 33,560 (288)

Role of Lipidomics in Respiratory Tract Infections: A Systematic Review of Emerging Evidence [PDF]

Microorganisms
Lower respiratory tract infections (LRTIs) remain a major cause of global morbidity and mortality, yet accurate pathogen identification and risk stratification continue to pose clinical challenges.
Vasiliki E. Georgakopoulou, Konstantinos Dodos, Vassiliki C. Pitiriga   +2 more
doaj   +2 more sources

The Expanded Endocannabinoid System Contributes to Metabolic and Body Mass Shifts in First-Episode Schizophrenia: A 5-Year Follow-Up Study

Biomedicines, 2022
Alterations in the expanded endocannabinoid system (eECS) and cell membrane composition have been implicated in the pathophysiology of schizophrenia spectrum disorders. We enrolled 54 antipsychotic (AP)-naïve first-episode psychosis (FEP) patients and 58
Madis Parksepp, Liina Haring, Kalle Kilk, Kadri Koch, Kärt Uppin, Raul Kangro, Mihkel Zilmer, Eero Vasar   +7 more
doaj   +1 more source

Associations of Early Pregnancy Metabolite Profiles with Gestational Blood Pressure Development

Metabolites, 2022
Blood pressure development plays a major role in both the etiology and prediction of gestational hypertensive disorders. Metabolomics might serve as a tool to identify underlying metabolic mechanisms in the etiology of hypertension in pregnancy and lead ...
Sophia M. Blaauwendraad, Rama J. Wahab, Bas B. van Rijn, Berthold Koletzko, Vincent W. V. Jaddoe, Romy Gaillard   +5 more
doaj   +1 more source

Metabolomics to unveil and understand phenotypic diversity between pathogen populations [PDF]

, 2010
Visceral leishmaniasis is caused by a parasite called Leishmania donovani, which every year infects about half a million people and claims several thousand lives. Existing treatments are now becoming less effective due to the emergence of drug resistance.
A Kamleh, A Scalbert, AK Chavali, Andris Jankevics, BO Keller, C Bern, C Christin, CC HsuChen, D Kumar, David G. Watson, DS Wishart, E Cauchetier, E Fahy, F Chappuis, F Hong, FR Opperdoes, G Barratt, Graham H. Coombs, H Ogata, HC Maltezou, HJ Atherton, HP de Koning, HW Murray, J Alvar, J Trygg, J Vandesompele, JC Mottram, Jean-Claude Dujardin, JV Olsen, K Zhang, K Zhang, Kirstyn Brunker, KW Tintaya, M Basselin, M Basselin, M Rakotomanga, MA Basinger, MA Doyle, MA Kamleh, MA Kamleh, MB Eisen, MK Wassef, MZ Alam, N Mbongo, N Van Meirvenne, R Breitling, R Breitling, R Breitling, RA Scheltema, RA Scheltema, RA Scheltema, Rainer Breitling, Richard A. Scheltema, Ruben t'Kindt, S Rijal, S Sundar, Saskia Decuypere, Suman Rijal, T Laurent, T Naderer, Timothy G. Geary, VP Shah, W Windig, WB Dunn   +63 more
core   +11 more sources

Discovery of Sexual Dimorphisms in Metabolic and Genetic Biomarkers [PDF]

, 2011
Metabolomic profiling and the integration of whole-genome genetic association data has proven to be a powerful tool to comprehensively explore gene regulatory networks and to investigate the effects of genetic variation at the molecular level.
A Brandstätter, A Döring, A Köttgen, A Lorber, AA Hicks, Alexey Polonikov, AM Kim, Annette Peters, C Gieger, Christian Gieger, CM Rodrigues, CM Slupsky, CM Tingen, Cornelia Prehn, D Fairweather, Fabian J. Theis, Florian Kronenberg, G Paré, H Löwel, H-E Wichmann, Heinz Erich Wichmann, I Pe'er, J Krumsiek, J Nikkilä, J Yeboah, Jan Krumsiek, Janina S. Ried, Jerzy Adamski, JQ Purnell, Karsten Suhre, Kirstin Mittelstrass, LA Lange, M Steffens, Mark I. McCarthy, ML Summar, P Filzmoser, R Holle, R Paternoster, Rui Wang-Sattler, SE Geller, SE Reuter, Stephan Weidinger, T Illig, Thomas Illig, Thomas Meitinger, W Mostertz, Werner Roemisch-Margl, WL Holland, YS Aulchenko, Zhonghao Yu   +49 more
core   +6 more sources

Unique Distribution of Diacyl-, Alkylacyl-, and Alkenylacyl-Phosphatidylcholine Species Visualized in Pork Chop Tissues by Matrix-Assisted Laser Desorption/Ionization–Mass Spectrometry Imaging

Foods, 2020
Phosphatidylcholine (PC) is the major phospholipid in meat and influences meat qualities, such as healthiness. PC is classified into three groups based on the bond at the sn-1 position: Diacyl, alkylacyl, and alkenylacyl. To investigate their composition
Hirofumi Enomoto, Tomohiro Furukawa, Shiro Takeda, Hajime Hatta, Nobuhiro Zaima   +4 more
doaj   +1 more source

Synthesis, Characterization, and In Vitro Cancer Cell Growth Inhibition Evaluation of Novel Phosphatidylcholines with Anisic and Veratric Acids

Molecules, 2018
Phenolic acids and its methoxy derivatives are known to induce caspase-mediated apoptosis activity and exhibit cytotoxic effect towards various cancer cell lines.
Marta Czarnecka, Marta Świtalska, Joanna Wietrzyk, Gabriela Maciejewska, Anna Gliszczyńska   +4 more
doaj   +1 more source

Differential determination of phospholipase A2 and PAF-acetylhydrolase in biological fluids using fluorescent substrates

Journal of Lipid Research, 1999
The purpose of the present study was the development and evaluation of a fluorimetric method for the screening and differential determination of phospholipase A2 and PAF-acetylhydrolase in bronchoalveolar lavage (BAL) fluid and serum.
Eirini I. Kitsiouli, George Nakos, Marilena E. Lekka   +2 more
doaj   +1 more source

Phosphatidylcholines from Pieris brassicae eggs activate an immune response in Arabidopsis

eLife, 2020
Recognition of conserved microbial molecules activates immune responses in plants, a process termed pattern-triggered immunity (PTI). Similarly, insect eggs trigger defenses that impede egg development or attract predators, but information on the nature ...
Elia Stahl, Théo Brillatz, Emerson Ferreira Queiroz, Laurence Marcourt, André Schmiesing, Olivier Hilfiker, Isabelle Riezman, Howard Riezman, Jean-Luc Wolfender, Philippe Reymond   +9 more
doaj   +1 more source

Dietary N-3 polyunsaturated fatty acids decrease biliary cholesterol saturation in gallstone disease [PDF]

, 1992
Because fatty acid composition of biliary phospholipids influences cholesterol secretion into bile, we investigated whether replacement of n-1 monounsaturated or n-6 polyunsaturated fatty acids with n-3 polyunsaturated fatty acids in biliary ...
Abell, Ahlberg, Balasubramaniam, Barlett, Bernd Seifferth, Berr, Berr, Berr, Berr, Carey, Carey, Carulli, Cohen, Cohen, Coleman, Dam, Delchier, Dieter Jüngst, Everson, Frieder Berr, Glenn, Goodnight, Gustav Paumgartner, Harris, Hofmann, Holan, Holzbach, Joseph Holl, Juniper, Kaludzny, Kelly, Kuroki, Leaf, Lee, Lippel, Lorenz, Magnuson, Marks, Nestel, Nestel, O'Leary, Parhofer, Paul, Phillipson, Pomeranz, Ramond, Robins, Robins, Sanders, Scobey, Sedaghat, Snedecor, Strasberg, Sven Fischer, Sömjen, Ventura, von Schacky, Wagner, Wechsler, Werner O. Richter   +59 more
core   +1 more source