Results 1 to 10 of about 14,174 (197)

Mucosal Protection by Phosphatidylcholine [PDF]

Digestive Diseases, 2012
The colonic mucus serves a first barrier towards invasion of commensal bacteria in stools to prevent inflammation. One essential component of intestinal mucus is phosphatidylcholine (PC) which represents more than 90% of the phospholipids in mucus indicative for a selective transport of PC into this compartment. It is arranged in lamellar structures as
Stremmel, Wolfgang, Ehehalt, Robert, Staffer, Sabine, Stoffels, Sabine, Mohr, Andrea, Karner, Max, Braun, Annika   +6 more
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Miscibility of Sphingomyelins and Phosphatidylcholines in Unsaturated Phosphatidylcholine Bilayers [PDF]

Biophysical Journal, 2015
Polyunsaturated phospholipids are common in biological membranes and affect the lateral structure of bilayers. We have examined how saturated sphingomyelin (SM; palmitoyl and stearoyl SM (PSM and SSM, respectively)) and phosphatidylcholine (PC; dipalmitoyl PC and 1-palmitoyl-2-stearoyl PC (DPPC and PSPC, respectively)) segregate laterally to form ...
Kullberg Anders, Slotte J Peter, Ekholm Oscar   +2 more
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Barbiturate Interaction with Phosphatidylcholine [PDF]

Proceedings of the National Academy of Sciences, 1972
A hydrogen-bonding interaction between phenobarbital or pentobarbital with phosphatidylcholine in chloroform is indicated by the effects of added phosphatidylcholine on the infrared and proton magnetic resonance spectra of these barbiturates. The nitrogenbound proton of the barbiturate and the orthophosphate moiety of the phosphatidylcholine molecule ...
R F, Novak, T J, Swift
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Anti-inflammatory Effects of Phosphatidylcholine [PDF]

Journal of Biological Chemistry, 2007
We recently showed that mucus from patients with ulcerative colitis, a chronic inflammatory disorder of the colon, is characterized by a low level of phosphatidylcholine (PC) while clinical studies reveal that therapeutic addition of PC using slow release preparations is beneficial. The positive role of PC in this disease is still elusive.
Treede, Irina, Braun, Annika, Sparla, Richard, Kuehnel, Mark, Giese, Thomas, Turner, Jerrold R., Anes, Elsa, Kulaksiz, Hasan, Fuellekrug, Joachim, Stremmel, Wolfgang, Griffiths, Gareth, Ehehalt, Robert   +11 more
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Phosphatidylcholine transfer protein from bovine liver contains highly unsaturated phosphatidylcholine species [PDF]

FEBS Letters, 1996
The phosphatidylcholine transfer protein (PC‐TP) from bovine liver contains one molecule of non‐covalently bound PC. In order to gain more insight into the physiological function of PC‐TP, PC was extracted from bovine liver PC‐TP and its molecular species composition identified by fast atom bombardment mass spectrometry.
Geijtenbeek, T. B., Westerman, J., Heerma, W., Wirtz, K. W.   +3 more
openaire   +2 more sources

Viscosity of phosphatidylcholine (lecithin)

Journal of Pharmacy and Pharmacology, 1966
AbstractThe viscosities of egg lecithin dispersed in water have been measured by means of a Couette viscometer. The more concentrated dispersions are thixotropic, but below 1·8% w/w of lecithin the sols become Newtonian. From the extrapolated ratio of specific viscosity to volume fraction, the dispersed particles are considered to be of an elongated ...
J H, Perrin, L, Saunders
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Phosphatidylcholine: cholesterol phase diagrams.

Biophysical journal, 2010
Two mono-cis-unsaturated phosphatidylcholine (PC) lipid molecules, having very different gel-liquid crystalline phase transition temperatures as a consequence of the relative positions of the double bond, exhibit PC:cholesterol phase diagrams that are very similar to each other and to that obtained previously for a fully saturated PC:cholesterol ...
Thewalt, Jenifer L., Bloom, Myer
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Expansion of Phosphatidylcholine and Phosphatidylserine/Phosphatidylcholine Monolayers by Differently Charged Amphiphiles

Zeitschrift für Naturforschung C, 2001
Abstract Monolayer Technique, Nonionic Detergent, Erythrocyte Shape The degree and time-course of expansion of palmitoyloleoylphosphatidylcholine (PC) and bovine brain phosphatidylserine (PS)/PC (75:25, mol/mol) monolayers at 32 mN/m caused by differently charged amphiphiles (detergents) added to the sub-phase buffer (pH 7.4, 22 °C ...
K, Białkowska, M, Bobrowska-Hägerstrand, H, Hägerstrand   +2 more
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Phosphatidylcholine

Biophysical Journal, 1992
Thewalt, Jenifer L., Bloom, Myer
openaire   +1 more source

Comprehensive first-trimester targeted metabolomics for early prediction and understanding of GDM pathophysiology. [PDF]

Front Mol Biosci
Mojsak P, Godlewski A, Sołowiej K, Kulczynska-Przybik A, Chmielewska S, Mroczko B, Szelachowska M, Krętowski A, Ciborowski M.   +8 more
europepmc   +1 more source